That Chemist Archive Channel

Like and subscribe. This is an archive channel, i'm not the owner of the content, check the link in the end. In this video, I decide which oxidizers are best! https://www.patreon.com/thatchemist Community Discord - https://discord.gg/QWNPETtPcZ https://rumblevideoarchive.wordpress.com/

Like and subscribe. This is an archive channel, i'm not the owner of the content, check the link in the end. In this video, I discuss the use of... unripe banana water as a 'medium' for the benzoylation of aniline... https://www.patreon.com/thatchemist Community Discord - https://discord.gg/QWNPETtPcZ ---------------------------------------------------------------------------------------------------------------------------------- Links to articles discussed in this episode: Banana Water Paper - https://www.doi.org/10.21767/2572-4657.100008 ---------------------------------------------------------------------------------------------------------------------------------- https://rumblevideoarchive.wordpress.com/

Like and subscribe. This is an archive channel, i'm not the owner of the content, check the link in the end. In this video, I discuss the formation of peroxides in common solvents. Make sure you check with the guidelines from your institutional EH&S department before dealing with peroxide-forming solvents! https://www.patreon.com/thatchemist Community Discord - https://discord.gg/QWNPETtPcZ ---------------------------------------------------------------------------------------------------------------------------------- Links to articles discussed in this episode: Diisopropyl ether bog - https://www.doi.org/10.1021/ed040p469 https://ehs.ucsc.edu/lab-safety-manual/specialty-chemicals/peroxide-formers-list.html https://ehs.ucsc.edu/lab-safety-manual/specialty-chemicals/peroxide-formers.html https://www.sfu.ca/content/dam/sfu/srs/work-research-safety/research-safety/Chemical%20safety/2019%20Chemical%20safety%20fact%20sheet%20peroxide%20formers.pdf https://www.sigmaaldrich.com/PA/en/technical-documents/technical-article/chemistry-and-synthesis/reaction-design-and-optimization/peroxide-formation https://ehs.berkeley.edu/news/peroxide-explosion-injures-campus-researcher Other J Chem Ed paper- https://www.doi.org/10.1021/ed013p494 ---------------------------------------------------------------------------------------------------------------------------------- https://rumblevideoarchive.wordpress.com/

Like and subscribe. This is an archive channel, i'm not the owner of the content, check the link in the end. In this video, I discuss five important papers in organic synthesis that were published in May 2022. https://www.patreon.com/thatchemist Community Discord - https://discord.gg/QWNPETtPcZ ---------------------------------------------------------------------------------------------------------------------------------- Links to articles discussed in this episode: first paper - https://www.doi.org/10.1021/acs.orglett.2c01174 second paper - https://www.doi.org/10.1021/acs.orglett.2c01410 third paper - https://www.doi.org/10.1021/jacs.2c02922 fourth paper - https://www.doi.org/10.1021/jacs.2c02795 fifth paper - https://www.doi.org/10.1038/s41586-022-04516-4 Bonus papers amino acid - https://www.doi.org/10.1021/acs.joc.2c00524 matteson - https://www.doi.org/10.1021/jacs.2c03621 cyclopropanone - https://www.doi.org/10.1021/jacs.2c03673 carborane - https://www.doi.org/10.1021/jacs.2c03031 hydrofluoroalkylation - https://www.doi.org/10.1021/acs.joc.2c00712 quinoline N-oxide - https://www.doi.org/10.1126/science.abo4282 ---------------------------------------------------------------------------------------------------------------------------------- https://rumblevideoarchive.wordpress.com/

Like and subscribe. This is an archive channel, i'm not the owner of the content, check the link in the end. In this video, I discuss the best way to dry THF, toluene, DCM, MeCN, methanol, ethanol, HMPA, DMF, DMSO, acetone, benzene, and 1,4-dioxane. https://www.patreon.com/thatchemist Community Discord - https://discord.gg/QWNPETtPcZ ---------------------------------------------------------------------------------------------------------------------------------- Links to articles discussed in this episode: newest paper - https://www.doi.org/10.1021/jo101589h https://www.doi.org/10.1021/jo00414a038 https://www.doi.org/10.1021/jo00438a024 ---------------------------------------------------------------------------------------------------------------------------------- https://rumblevideoarchive.wordpress.com/

Like and subscribe. This is an archive channel, i'm not the owner of the content, check the link in the end. In this video, I discuss the falsification of NMR spectra in published articles. I WAS INCORRECT - Janine Cossy was an editor for Organic Letters when her Organic Letters article was 'corrected'. She also had a paper in JOC which was 'corrected' around the same time. There is still a conflict of interest in my opinion, but it is important to note that she was an editor for a different journal when the falsified data for the JOC article was revised. https://www.patreon.com/thatchemist Community Discord - https://discord.gg/QWNPETtPcZ ---------------------------------------------------------------------------------------------------------------------------------- Links to articles discussed in this episode: retraction notice - https://www.doi.org/10.1021/jacs.0c11624 express of concern - https://www.doi.org/10.1021/jacs.0c02795 hydrodefluorination - https://www.doi.org/10.1021/jacs.7b06847 Type 1 from Chem Sci - https://www.doi.org/10.1039/C2SC20639K Type 1 from org lett - https://www.doi.org/10.1021/ol2015972 blog post - https://web.archive.org/web/20200820212832/http://blog.chembark.com/2013/08/19/some-very-peculiar-nmr-spectra-in-organic-letters/ 2nd blog post - https://web.archive.org/web/20150912170942/http://blog.chembark.com/wp-content/uploads/2013/08 Bonus Cossy article - https://www.doi.org/10.1021/jo300887u Correction from OBC - https://www.doi.org/10.1039/D0OB90089C 3rd blog post - https://retractionwatch.com/2019/03/06/a-university-thought-its-misconduct-investigation-was-complete-then-a-pubpeer-comment-appeared/ ---------------------------------------------------------------------------------------------------------------------------------- https://rumblevideoarchive.wordpress.com/

Like and subscribe. This is an archive channel, i'm not the owner of the content, check the link in the end. In this video, I decide which base is the best! Let me know down in the comments if you disagree with any of my assessments! https://www.patreon.com/thatchemist Community Discord - https://discord.gg/QWNPETtPcZ ------------------------------------------------------------------------------------------------------------------ Organic Letters Paper - https://doi.org/10.1021/acs.orglett.0c00099 ------------------------------------------------------------------------------------------------------------------ https://rumblevideoarchive.wordpress.com/

Like and subscribe. This is an archive channel, i'm not the owner of the content, check the link in the end. Dealing with failure is one of the most challenging struggles as a scientist - we all experience it, and it can be challenging to cope with failure. https://www.patreon.com/thatchemist Community Discord - https://discord.gg/QWNPETtPcZ https://rumblevideoarchive.wordpress.com/

Like and subscribe. This is an archive channel, i'm not the owner of the content, check the link in the end. In this episode, I discuss oxidations with DMP, PCC, and Swern. Aldehydes are reactive intermediates, and methods for their synthesis are important! ---------------------------------------------------------------------------------------------------------------------------------- Links to articles discussed in this episode: first DMP - https://doi.org/10.1021/acs.joc.9b02378 second DMP - https://doi.org/10.1039/c1ob05612c third DMP - https://doi.org/10.1021/acs.orglett.5b01601 first PCC - https://patents.google.com/patent/WO2018068297A1/en second PCC - https://doi.org/10.3390/molecules23061422 first Swern - https://patents.google.com/patent/WO2012062157A1/en second Swern - https://doi.org/10.1016/0040-4039(90)80121-2 ---------------------------------------------------------------------------------------------------------------------------------- I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! Recommended Texts: J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016. LibreTexts: https://chem.libretexts.org/Bookshelves/Organic_Chemistry https://rumblevideoarchive.wordpress.com/

Like and subscribe. This is an archive channel, i'm not the owner of the content, check the link in the end. In this video, I discuss the reduction of carbonyl compounds with sodium borohydride (NaBH4) and lithium aluminum hydride (LiAlH4). ---------------------------------------------------------------------------------------------------------------------------------- Links to articles discussed in this episode: NotVoodooX - http://www.chem.rochester.edu/notvoodoo/ NaBH4 review - https://doi.org/10.1002/047084289X.rs052.pub3 first NaBH4 - https://doi.org/10.1021/jacs.7b12260 second NaBH4 - https://doi.org/10.1002/anie.201700190 third NaBH4 - https://doi.org/10.1016/j.jfluchem.2004.12.006 Fieser workup - http://www.chem.rochester.edu/notvoodoo/pages/magic_formulas.php?page=aluminum_hydride_reduction first LAH - https://doi.org/10.1021/ja0469030 second LAH - https://doi.org/10.1021/jo301790q third LAH - https://doi.org/10.1002/ajoc.201600429 alkyl halide LAH - https://doi.org/10.1021/jo00341a018 ---------------------------------------------------------------------------------------------------------------------------------- I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! Recommended Texts: J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016. LibreTexts: https://chem.libretexts.org/Bookshelves/Organic_Chemistry https://rumblevideoarchive.wordpress.com/

This is an archive channel, i'm not the owner of the content, check the link in the end. I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! ---------------------------------------------------------------------------------------------------------------------------------- Links to articles discussed in this episode: enolate formation - https://doi.org/10.1021/jo00268a037 ---------------------------------------------------------------------------------------------------------------------------------- Recommended Texts: J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016. LibreTexts: https://chem.libretexts.org/Bookshelves/Organic_Chemistry https://rumblevideoarchive.wordpress.com/

Like and subscribe. This is an archive channel, i'm not the owner of the content, check the link in the end. In this video, I discuss Mukaiyama Aldol reactions, in addition to Boron Aldol reactions. Boron enolates can be prepared with really good E/Z selectivity, often much better than TMS-enolates. ---------------------------------------------------------------------------------------------------------------------------------- Links to articles discussed in this episode: base choice - https://doi.org/10.1021/jo00268a037 Mukaiyama - https://www.organic-chemistry.org/namedreactions/mukaiyama-aldol-addition.shtm boron aldol - https://doi.org/10.1021/jo00020a025 kinetic boron enolate - https://doi.org/10.1021/ja00191a058 thermodynamic boron enolate - https://doi.org/10.1021/jo00020a025 tms-enolates from boron enolates - https://doi.org/10.1016/S0040-4039(00)94175-3 ---------------------------------------------------------------------------------------------------------------------------------- I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! Recommended Texts: J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016. LibreTexts: https://chem.libretexts.org/Bookshelves/Organic_Chemistry https://rumblevideoarchive.wordpress.com/

Like and subscribe. This is an archive channel, i'm not the owner of the content, check the link in the end. *Disclaimer* LDA can also afford E-enolates, and usually a mixture is obtained; if an ester or an amide is used instead of a ketone, the selectivity can change! Depending on the ketone that is used, the selectivity can also reverse. ---------------------------------------------------------------------------------------------------------------------------------- Links to articles discussed in this episode: first lithium aldol - https://doi.org/10.1039/D0SC06223E second lithium aldol - https://doi.org/10.1002/chem.201502754 Ben List - https://doi.org/10.1021/ja994280y Nobel Prize - https://www.nobelprize.org/prizes/chemistry/2021/list/lecture/ proline aldol example - https://doi.org/10.1126/science.abb3231 ---------------------------------------------------------------------------------------------------------------------------------- I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! Recommended Texts: J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016. LibreTexts: https://chem.libretexts.org/Bookshelves/Organic_Chemistry https://rumblevideoarchive.wordpress.com/

This is an archive channel, i'm not the owner of the content, check the link in the end. In this video, I discuss aldol condensation reactions between aldehydes and ketones, which produce Michael acceptors (alpha-beta unsaturated carbonyl compounds). ---------------------------------------------------------------------------------------------------------------------------------- Links to articles discussed in this episode: N-parameter database - https://www.cup.lmu.de/oc/mayr/reaktionsdatenbank2 ---------------------------------------------------------------------------------------------------------------------------------- I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! Recommended Texts: J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016. LibreTexts: https://chem.libretexts.org/Bookshelves/Organic_Chemistry https://rumblevideoarchive.wordpress.com/

This is an archive channel, i'm not the owner of the content, check the link in the end. If you like the way I explained the concept of 1,4-addition using electrophilicity and nucleophilicity parameters, let me know in the comments!! ---------------------------------------------------------------------------------------------------------------------------------- Links to articles discussed in this episode: N-parameter database - https://www.cup.lmu.de/oc/mayr/reaktionsdatenbank2 Mayr's website - https://www.cup.uni-muenchen.de/oc/mayr/research.html sulfur addition - https://doi.org/10.1021/jo00112a025 nitrogen addition - https://patents.google.com/patent/WO2012028331A1/en enolate addition - https://doi.org/10.1021/jo01031a059 enamine addition - https://doi.org/10.1002/mrc.1270220705 ---------------------------------------------------------------------------------------------------------------------------------- I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! Recommended Texts: J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016. LibreTexts: https://chem.libretexts.org/Bookshelves/Organic_Chemistry https://rumblevideoarchive.wordpress.com/

This is an archive channel, i'm not the owner of the content, check the link in the end. I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! ---------------------------------------------------------------------------------------------------------------------------------- Links to articles discussed in this episode: cuprate addition - https://doi.org/10.1002/0471264180.or019.01 cuprate alkylation - https://doi.org/10.1021/ja00195a042 ketone formation - https://doi.org/10.1016/S0040-4039(00)89398-3 ---------------------------------------------------------------------------------------------------------------------------------- Recommended Texts: J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016. LibreTexts: https://chem.libretexts.org/Bookshelves/Organic_Chemistry https://rumblevideoarchive.wordpress.com/

This is an archive channel, i'm not the owner of the content, check the link in the end. I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! ---------------------------------------------------------------------------------------------------------------------------------- Links to articles discussed in this episode: CH3Li - https://doi.org/10.1002/047084289X.rm205.pub2 Lithium alkynide - https://doi.org/10.1055/s-0035-1560587 C-H lithiation example - https://doi.org/10.1002/047084289X.rm205.pub2 nBuLi - https://doi.org/10.1002/047084289X.rb395.pub2 ---------------------------------------------------------------------------------------------------------------------------------- Recommended Texts: J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016. LibreTexts: https://chem.libretexts.org/Bookshelves/Organic_Chemistry https://rumblevideoarchive.wordpress.com/

This is an archive channel, i'm not the owner of the content, check the link in the end. I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! Recommended Texts: J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016. LibreTexts: https://chem.libretexts.org/Bookshelves/Organic_Chemistry https://rumblevideoarchive.wordpress.com/

This is an archive channel, i'm not the owner of the content, check the link in the end. I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! Recommended Texts: J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016. LibreTexts: https://chem.libretexts.org/Bookshelves/Organic_Chemistry https://rumblevideoarchive.wordpress.com/

This is an archive channel, i'm not the owner of the content, check the link in the end. Here is the link to the Organic Syntheses article using trimethyl orthoformate: http://orgsyn.org/demo.aspx?prep=v75p0170 I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! Recommended Texts: J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016. LibreTexts: https://chem.libretexts.org/Bookshelves/Organic_Chemistry https://rumblevideoarchive.wordpress.com/

This is an archive channel, i'm not the owner of the content, check the link in the end. I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! Recommended Texts: J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016. LibreTexts: https://chem.libretexts.org/Bookshelves/Organic_Chemistry https://rumblevideoarchive.wordpress.com/

This is an archive channel, i'm not the owner of the content, check the link in the end. I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! Recommended Texts: J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016. LibreTexts: https://chem.libretexts.org/Bookshelves/Organic_Chemistry https://rumblevideoarchive.wordpress.com/

This is an archive channel, i'm not the owner of the content, check the link in the end. I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! Recommended Texts: J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016. LibreTexts: https://chem.libretexts.org/Bookshelves/Organic_Chemistry https://rumblevideoarchive.wordpress.com/

This is an archive channel, i'm not the owner of the content, check the link in the end. I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! Recommended Texts: J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016. LibreTexts: https://chem.libretexts.org/Bookshelves/Organic_Chemistry https://rumblevideoarchive.wordpress.com/

This is an archive channel, i'm not the owner of the content, check the link in the end. I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! Recommended Texts: J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016. LibreTexts: https://chem.libretexts.org/Bookshelves/Organic_Chemistry https://rumblevideoarchive.wordpress.com/