That Chemist Archive Channel

191023 Go to https://ground.news/thatchemist to know where your information is coming from. Get 30% off their unlimited vantage plan or try out their pro plan for less than $1/month. Super bases are extremely strong bases, so strong that they get their own special designation. You must be super based if you are watching this video. Support the Channel on Patreon - https://www.patreon.com/thatchemist Join the Community Discord! - https://discord.gg/thatchemist Second Discord link if the first one is borked - https://discord.gg/QWNPETtPcZ *Team* Writer/Producer/Thumbnail Artist - That Chemist (Joey) Lead Animator/Graphic Designer/Editor – David Vinamidine paper - https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.198711641 PKBH table - https://doi.org/10.2478/s11532-010-0044-9 Physico-Chemical Properties of Organosuperbases -https://doi.org/10.1002/9780470740859.ch2 Pandora's Phosphazene - https://onlinelibrary.wiley.com/doi/10.1002/anie.199313611 DMF/DMSO/DMA + NaH hazards - https://pubs.acs.org/doi/10.1021/acs.oprd.9b00276

041123 Subscribe to Curiosity Stream and start exploring the world around you! https://bit.ly/CuriosityStreamThatChemist1123 Plants can just poke you and then you need to go to the hospital? That sure is irritating. Support the Channel on Patreon - https://www.patreon.com/thatchemist Join the Community Discord! - https://discord.gg/thatchemist Second Discord link if the first one is borked - https://discord.gg/QWNPETtPcZ *Team* Writer/Producer/Thumbnail Artist - That Chemist (Joey) Lead Writer/Editor – @CiggySnake

071023 You can get your very own Eco Funnels by going to https://www.calpaclab.com/eco-funnels/ and using code *thatchemist10* to get 10% off site-wide. Thanks to CP Lab Safety for supporting the channel! This is an episode in the Extreme Chempilation series - expect mild profanity and stories that some viewers may find disturbing. DO NOT EAT OR DRINK LAB CHEMICALS! 💀💀💀 I want to give a huge thanks to all the supporters of the channel on Patreon! https://www.patreon.com/thatchemist Join the Community Discord! - https://discord.gg/thatchemist *Team* Producer/Host - Joey (That Chemist) Production Assistant/Editor - Exergonick

051023 Sam (Chemiolis) claims to have made cubane, but how do we really know that he did? In this video we dive into Sam's cubane & geosmin samples, and we examine their NMR spectra. How should we do chemistry on YouTube? I discuss all this and more. Sam was honest and open in the preparation of this video - @Chemiolis @ExtractionsAndIre will make cubane eventually... A big thanks to ArgonLover for reviewing some of the research. Lead Editor/Animator - David Producer/Host - Joey (TC) Particle Animator - RobotChicken Support the Channel on Patreon - https://www.patreon.com/thatchemist Join the Community Discord! - https://discord.gg/thatchemist Second Discord link if the first one is borked - https://discord.gg/QWNPETtPcZ Links to the videos where @Chemiolis makes cubane and geosmin: Cubane part 1 https://www.youtube.com/watch?v=zjp1aR6dSh4 Cubane part 2 https://www.youtube.com/watch?v=v6jqlL5ZT3M Geosmin https://www.youtube.com/watch?v=bl7K3lRPLYo

011023 Interested in boosting success rates in synthesis route design and prediction using the Predictive Retrosynthesis Tool from Reaxys? Find out more information here - https://beta.elsevier.com/products/reaxys/predictive-retrosynthesis?utm_campaign=prt-integration-ads&utm_source=thatchemist&utm_medium=video&dgcid=RN_AG_Sourced_400004103 Important Papers covers various chemical reactions, mechanisms, and research papers in the field of organic chemistry, providing examples and explanations for each research paper. In this video, I discuss five important papers in organic synthesis that were published around September 2023. Make sure you share this series with other chemists in your network, especially ones who don't usually watch YouTube! I want to thank Maurice Hietkamp for his help with this episode :) Support the Channel on Patreon - https://www.patreon.com/thatchemist Join the Community Discord! - https://discord.gg/thatchemist Backup Discord link - https://discord.gg/QWNPETtPcZ Important Papers Playlist - https://youtube.com/playlist?list=PL6OLqxmk7RtyRkdJhXK8NWpT1krGNq1p4 ----------------------------------------- References: Ethers from esters https://doi.org/10.1021/acs.orglett.3c02643 Sulfonamides from alcohols https://doi.org/10.1021/jacs.3c08216 Ethers from carbonyls https://doi.org/10.1021/acs.joc.3c00822 BMIDA acrolein https://doi.org/10.1021/acscatal.3c03474 Nitrosyl Triflate https://doi.org/10.1021/acs.orglett.3c02700 ----------------------------------------- Honorable mentions: Ergoline Synthesis https://doi.org/10.1021/acs.joc.3c01363 C−H Fluorination of Quinolines https://doi.org/10.1021/jacs.3c07119 Aryl (β,β′,β″-Trifluoro)-tert-butyl https://doi.org/10.1021/acs.orglett.3c02236 Carbenes Derived from Dichloromethane https://doi.org/10.1002/anie.202308913 The NBS DMF OPRD paper https://doi.org/10.1021/acs.oprd.3c00104

260923 Super acids are extremely strong acids, so strong that they get their own special designation. Are you a registered super acid? Support the Channel on Patreon - https://www.patreon.com/thatchemist Join the Community Discord! - https://discord.gg/thatchemist Second Discord link if the first one is borked - https://discord.gg/QWNPETtPcZ

290923 Thanks to Bespoke Post for sponsoring this video! New subscribers get 20% off their first box of awesome — go to https://bespokepost.com/thatchemist20 and enter code THATCHEMIST20 at checkout. Support the Channel on Patreon - https://www.patreon.com/thatchemist Join the Community Discord! - https://discord.gg/thatchemist Second Discord link if the first one is borked - https://discord.gg/QWNPETtPcZ Check out the selenium video from LabCoatz - https://www.youtube.com/watch?v=031vrZAMEHU A sneezing agent is also known as a 'sternutator' https://www.merriam-webster.com/dictionary/sternutator

120923 This video discusses the scheduling of several common drugs within the United States. Hopefully this goes without saying - this video is not legal advice, usually if people want legal advice they pay a lawyer. ---------------------------------------------------------------------------------------- Clarifications: THC is Schedule II for Syndros, one formulation of THC, and THC is actually Schedule III for Marinol, another formulation of THC, but aside from these products, THC is Schedule I Sodium oxybate (a salt of GHB) is also listed as Schedule III even though GHB is Schedule I ----------------------------------------------------------------------------------------- https://en.wikipedia.org/wiki/Controlled_Substances_Act Support the Channel on Patreon - https://www.patreon.com/thatchemist Join the Community Discord! - https://discord.gg/thatchemist You can check out Jordan's book "Bizarro: The Surreal Saga of America’s Secret War on Synthetic Drugs and the Florida Kingpins It Captured" here: https://www.amazon.com/Bizarro-Americas-Synthetic-Kingpins-Captured/dp/0520387953 (non-affiliate link)

060923 Grab Atlas VPN for just $1.83/mo + 3 months extra before the SUMMER DEAL expires: https://get.atlasvpn.com/chemist 👈 #ad #atlasvpn This is an episode in the Extreme Chempilation series - expect mild profanity and stories that some viewers may find disturbing. DO NOT EAT OR DRINK OR SMOKE LAB CHEMICALS! 💀💀💀 I want to give a huge thanks to all the supporters of the channel on Patreon! https://www.patreon.com/thatchemist Join the Community Discord! - https://discord.gg/thatchemist *Team* Producer/Host - Joey (That Chemist) Production Assistant/Editor - Exergonick

010923 Interested in boosting success rates in synthesis route design and prediction using the Predictive Retrosynthesis Tool from Reaxys? Find out more information here - https://beta.elsevier.com/products/reaxys/predictive-retrosynthesis?utm_campaign=prt-integration-ads&utm_source=thatchemist&utm_medium=video&dgcid=RN_AG_Sourced_400004103 Important Papers covers various chemical reactions, mechanisms, and research papers in the field of organic chemistry, providing examples and explanations for each research paper. In this video, I discuss five important papers in organic synthesis that were published around August 2023. Make sure you share this series with other chemists in your network, especially ones who don't usually watch YouTube! I want to thank Maurice Hietkamp for his help with this episode :) Support the Channel on Patreon - https://www.patreon.com/thatchemist Join the Community Discord! - https://discord.gg/thatchemist Backup Discord link - https://discord.gg/QWNPETtPcZ Important Papers Playlist - https://youtube.com/playlist?list=PL6OLqxmk7RtyRkdJhXK8NWpT1krGNq1p4 ----------------------------------------- References: First Paper (Tetrazoles) - https://doi.org/10.1021/acs.orglett.3c02470 Second Paper (Azetidines) - https://doi.org/10.1021/jacs.3c06710 Third Paper (Hamigeran NPs) - https://doi.org/10.1021/jacs.3c06031 Fourth Paper (Ozone with Copper) - https://doi.org/10.1126/science.adi4758 Fifth Paper (Dabconium Ylide) - https://doi.org/10.1021/acs.oprd.3c00175 Supplemental Reading: Cyclopropane-1,1-dicarboxylic acid - https://doi.org/10.15227/orgsyn.060.0066 Tomkinson's Reagent (eEROS) - https://doi.org/10.1002/047084289X.rn01983 ----------------------------------------- Honorable mentions: Nitro-Containing Cubanes - https://doi.org/10.1021/acs.joc.3c00384 β-Substituted Pyrroles/Furans - https://doi.org/10.1021/acs.joc.3c01145 Chlorodiazirines - https://doi.org/10.1002/anie.202305081 Divarasib - https://doi.org/10.1021/acs.oprd.3c00164 Fluorodetriazenation - https://doi.org/10.1021/acs.joc.3c01239 Thionoesters from thioamides -https://doi.org/10.1021/acs.orglett.3c02238

230723 Like and subscribe. This is an archive, check the link in the end if you are owner. Grab Atlas VPN for just $1.83/mo + 3 months extra before the SUMMER DEAL expires: https://get.atlasvpn.com/chemist 👈 #ad #atlasvpn This is the neurotransmitter tier list – I hope you find this video to be very stimulating! I guess this is neurotransmitter lore ;) Support the Channel on Patreon - https://www.patreon.com/thatchemist Join the Community Discord! - https://discord.gg/thatchemist 0:00 Intro 4:53 Ad 6:15 Dopamine 9:30 GPCRs 14:39 Noradrenaline 17:42 Serotonin 21:25 Glutamate 24:55 GABA 27:00 Acetylcholine 29:35 Banana Outro 30:21 Dopamine (again?) *Team* Writer/Producer/Thumbnail Artist - That Chemist (Joey) Lead Animator/Graphic Designer/Editor – David Vesicle Animator - Chogi Lead Writer/Biochem Research - Exergonick (Nicholas) Writer/Biochem Research – Trev Chemistry Assistant - Maurice Technical Lead - Polygorg (Georg) Rigging/3D Systems Engineer - Robot Chicken *Acknowledgements* Ballerene for his ballin' biochem help *Music* - A huge thanks to @S3RL for letting us use his music in the video! "Dopamine - S3RL feat Sara" Contact S3RL - https://withkoji.com/@S3RL *References* Dopamine: https://www.kegg.jp/pathway/map00350+C03758, https://www.kegg.jp/pathway/map04728, https://www.genome.jp/pathway/hsa05012, https://www.kegg.jp/pathway/map05012+C03758 Noradrenaline: https://www.kegg.jp/entry/M00042 Serotonin: https://www.kegg.jp/pathway/map07211, https://www.kegg.jp/pathway/map04726 Tryptophan: https://www.kegg.jp/pathway/map04726+C00780 Glutamate: https://www.kegg.jp/kegg-bin/show_pathway?map04724 Gaba: https://www.kegg.jp/pathway/map04727 ACH: https://www.kegg.jp/pathway/map04725 Dopamine:Function & Symptoms: https://tinyurl.com/4cbw3ufd Acetylcholine in Learning and Memory: https://doi.org/10.1016/J.CONB.2006.09.002 Cholinergic Crisis: https://doi.org/10.1007/978-3-211-79280-3_237 Cholinesterase Inhibitors for Alzheimer’s: https://doi.org/10.1016/S0011-393X(03)00059-6 Myasthenia Gravis: https://doi.org/10.1212/CON.0000000000001161 Cholinergic Receptors: https://tinyurl.com/bdwec9j7 Otto Loewi: https://doi.org/10.11622/SMEDJ.2014002 Acetylcholine (ACh: https://tinyurl.com/5d4swfbm GABAergic Dysfunction: https://doi.org/10.1016/J.SEMCDB.2021.01.005 GABA Receptors: https://doi.org/10.1007/S11011-014-9560-1 The Neurobiology of Addiction: https://tinyurl.com/mryvu9bz Mechanism of Action - Benzodiazepine: https://tinyurl.com/3dycz4bu Anxiety Disorders and GABA Neurotransmission: https://doi.org/10.2147/NDT.S58841 Gamma-Aminobutyric Acid (GABA): https://tinyurl.com/mw58v55v Molecular Mechanisms GABAB: https://doi.org/10.1126/SCIADV.ABG3362 GABA and Glycine Receptors: https://tinyurl.com/2p9uvtrd GABA Receptor: https://tinyurl.com/yc6tv6cz NMDA Receptor-Dependent LTP/LTD: https://doi.org/10.1101/CSHPERSPECT.A005710 Glutamate and Depression: https://doi.org/10.5498/WJP.V11.I7.297 Glutamate Transporter 1: Target for the Treatment of Alcohol Dependence: https://doi.org/10.2174/092986712803530511 Glutamate: What It Is & Function: https://tinyurl.com/msk3z6we Glutamate Receptors: https://doi.org/10.1016/S0301-0082(01)00061-6 The History of (MSG): https://tinyurl.com/yt864se7 Serotonin Syndrome Case Report: https://doi.org/10.7759/CUREUS.22468 Brain Serotonergic Circuitries: https://doi.org/10.31887/DCNS.2010.12.4/YCHARNAY Abnormal Cells Constipation: https://doi.org/10.1080/003655299750025110 Serotonin: https://tinyurl.com/5d4swfbm Dopamine D1 Receptor: https://doi.org/10.3389/FNCEL.2021.806618 Dopamine in Motivational Control: https://doi.org/10.1016/j.neuron.2010.11.022 Norepinephrine: https://tinyurl.com/5cmbnma2 Adrenergic Neurons and Receptors: https://tinyurl.com/2s4fmw2m Noradrenergic Synapse: https://tinyurl.com/bdwec9j7 Adrenal Stress Hormones and Enhanced Memory for Emotionally Arousing Experiences: https://doi.org/10.1201/9781420008418.ch13 Dopamine and Noradrenaline in the Brain https://doi.org/10.3389/FNMOL.2019.00334 Noradrenergic Synapse: https://tinyurl.com/bdwec9j7 Dr Julius Axelrod: https://doi.org/10.1093/EURHEARTJ/EHAA200 Adrenal Gland: https://tinyurl.com/mv4jpauk Locus Coeruleus-Norepinephrine: https://doi.org/10.3389/FNAGI.2018.00127/BIBTEX Food-Related Reward Signals: https://doi.org/10.3402/FNR.V55I0.5955 Drugs Disrupt Presynaptic Dopamine Neurotransmission: https://doi.org/10.1016/J.NEURON.2011.02.010 Biochemistry, Dopamine Receptors: https://tinyurl.com/yc33pt4m Parkinson’s Disease: https://tinyurl.com/y84d2p7u Signaling Dopamine D1-like Receptor Activation: https://doi.org/10.1016/J.PHARMTHERA.2010.05.003 Ventral Tegmental Area, in Rat: https://doi.org/10.1016/j.neuroscience.2008.01.046 Arvid Carlsson: https://doi.org/10.4103/0019-5545.58907 Anatomy and Function of VTA : https://doi.org/10.3389/FNCIR.2022.867053/BIBTEX Dopamine in Motivational Control: https://doi.org/10.1016/j.neuron.2010.11.022 Relevant human Proteins found in RCSB PDB RCSB.org 10.1093/nar/28.1.235 And predicted proteins found at https://www.uniprot.org/ https://rumblevideoarchive.wordpress.com/

180823 Like and subscribe. This is an archive, check the link in the end if you are owner. In this video, I regale the stories of VidCon Anaheim, Open Sauce and Linus Tech Expo (LTX) 2023. Support the Channel on Patreon - https://www.patreon.com/thatchemist Join the Community Discord! - https://discord.gg/thatchemist *Links to Conference Websites* https://www.vidcon.com/anaheim/ https://opensauce.live/ https://www.ltxexpo.com/ https://www.cheminst.ca/conference/canadian-chemistry-conference-and-exhibition-2023/ *Timestamps* 0:00 Intro 0:58 VidCon Lore 11:31 DisneyLand Side Quest 13:33 Open Sauce Lore 20:54 Important NileRed Lore 25:11 LTX Lore 32:34 Linus Media Group Office Tour *YouTube Creators Mentioned in the Video* Safety Third @safetythird Will Osman @williamosman Other Safety Third Hosts @allenpan @TheBackyardScientist (Safety Third guest - Jake Laser @JLaservideo) Kibitz @ImKibitz @KibitzandtheCaptain John and Hank Green @vlogbrothers (they have several channels) MatPat and Steph @GameTheory @FilmTheory @FoodTheory @StyleTheorists Safiya Nygaard @safiya Tyler Williams @tylerwilliams Colin & Samir @ColinandSamir MrBeast Channel @MrBeast (I also got to see Ben, Will & Dustin) Nigel @NileRed @NileBlue Isaiah @PryorGaming Stephen @littleremyfood @worldaquatica Zack Freedman @ZackFreedman (thanks for the B-roll used in the video Zack!) Cody's Lab @theCodyReeder Tom @ExplosionsAndFire @ExtractionsAndIre Drake @styropyro Ben @AppliedScience Adam Savage @tested Rene (YT Creator Liaison) @ReneRitchie Wren @CorridorCrew @Corridor Justin @thethoughtemporium Matt Gray @MattGrayYES Hamilton Morris @HamiltonMorris Medhi @ElectroBOOM LTT @LinusTechTips ShortCircuit @ShortCircuit Louis Rossman @rossmanngroup Douglas @DMS3TV Tech Linked @techlinked Braethorn @braethorn Sara Dietschy @saradietschy *Videos I Used in this Video* Safety Third VidCon clip https://www.youtube.com/watch?v=41JYVKSvHMY Hextraction https://www.youtube.com/watch?v=Iqz7ZDdP25A Tom cubane video https://www.youtube.com/watch?v=M0yXy49ADQ8 Tom hamilton morris quote https://www.youtube.com/watch?v=mV_daaldE_I My interview with Hamilton https://www.youtube.com/watch?v=dtGMyKlJheY Safety Third Mall Santa Video https://www.youtube.com/watch?v=USBX2pIU71k ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ Braethorn LTX tour https://www.youtube.com/watch?v=3ItcVjhVru0 Sara Dietschy LTX tour https://www.youtube.com/watch?v=yVbel7iw7ZI Kibitz also has a vidcon vlog and an LTX vlog available through his Patreon - https://www.patreon.com/imkibitz *Music* - A huge thanks to @S3RL for letting us use his music in the video! "MTC - S3RL" "I Will Pick You Up - S3RL feat Tamika" Contact S3RL - https://withkoji.com/@S3RL *Other Vlogs for Open Sauce* ElectroBoom https://www.youtube.com/watch?v=3ajADL92vuU (I couldn't find any other good ones - if you comment one and I see it, I may add more) https://rumblevideoarchive.wordpress.com/

190823 Like and subscribe. This is an archive, check the link in the end if you are owner. This is an episode in the Extreme Chempilation series - expect mild profanity and stories that some viewers may find disturbing. Summary This YouTube video recounts various chemical mishaps and incidents experienced by individuals working with hazardous chemicals. Kenny's ammonia mishap serves as a cautionary tale, highlighting the dangers of anhydrous ammonia exposure even with safety gear. Other stories include incidents with cleaning chemicals, accidental exposure to hazardous gases, flawed chemical storage, and improper handling of dangerous compounds. These incidents emphasize the importance of proper training, safety protocols, and awareness when working with chemicals. Highlights 🔥 Kenny's mishap with anhydrous ammonia underscores the risks of exposure, despite safety precautions. 🧪 Mixing cleaning chemicals and improper handling can lead to harmful consequences, as shown by various accounts. 💣 Accidental exposure to hazardous gases and chemicals, like cyanide and refrigerants, can result in burns, lasting damage, and dangerous reactions. ⚠️ Neglecting proper storage and handling of chemicals, such as nitric acid and fluorosurfactants, can lead to leaks and dangerous situations. 🛡️ Proper training, safety protocols, and awareness are crucial in preventing chemical incidents and ensuring personal safety when working with hazardous substances. (The 'Summary' and 'Highlights' were generated using Glarity) DO NOT EAT OR DRINK OR SMOKE LAB CHEMICALS! 💀💀💀 I want to give a huge thanks to all the supporters of the channel on Patreon! https://www.patreon.com/thatchemist Join the Community Discord! - https://discord.gg/thatchemist *Team* Producer/Host - Joey (That Chemist) Production Assistant/Editor - Exergonick https://rumblevideoarchive.wordpress.com/

170623 Like and subscribe. This is an archive, check the link in the end if you are owner. This is an episode in the Extreme Chempilation series - expect mild profanity and stories that some viewers may find disturbing. Summary This video discusses various dangerous and reckless activities involving chemicals, highlighting incidents such as smoking brake cleaner, touching a red-hot stand, chewing burnt flesh, a steam explosion, burning oneself with isopropanol, explosive experiments with acetone, glycerin mishaps, poor hygiene practices, broken glassware due to shaking a test tube, drinking pure alcohol, and handling dry ice unsafely. The dangers and potential injuries associated with these activities are emphasized throughout the video. Highlights 💥 Smoking brake cleaner as a fuel for a cigarette 🤚 Touching a red-hot stand and chewing burnt flesh 💣 Steam explosion due to a superheated experiment 🔥 Burns from handling isopropanol and explosive experiments with acetone 💦 Glycerin reacting with nitration mix, causing nitrogen dioxide release 🧤 Poor hygiene practices leading to chemical contamination 🧪 Accidental transfer of a chemical causing numbness in sensitive areas 🧪 Nail going through a test tube while shaking it 🍺 Drinking pure alcohol in a lab experiment 🧪 Ethanol theft and missing containers from chem stores ❄️ Dangerous effects of dry ice on skin and metal 💥 Unsafe handling of dry ice and liquid nitrogen leading to explosions (The 'Summary' and 'Highlights' were generated using Glarity) DO NOT EAT OR DRINK OR SMOKE LAB CHEMICALS! 💀💀💀 I want to give a huge thanks to all the supporters of the channel on Patreon! https://www.patreon.com/thatchemist The supporters on Patreon have decided to release the Patreon chempilations! We will be gradually releasing them after they get some minor editing. These will be known as Extreme Chempilations. This was the September 2022 Patreon Chempilation, until the Patrons changed the way things work :) Join the Community Discord! - https://discord.gg/thatchemist https://rumblevideoarchive.wordpress.com/

030823 Like and subscribe. This is an archive, check the link in the end if you are owner. Interested in boosting success rates in synthesis route design and prediction using the Predictive Retrosynthesis Tool from Reaxys? Find out more information here - https://beta.elsevier.com/products/reaxys/predictive-retrosynthesis?utm_campaign=prt-integration-ads&utm_source=thatchemist&utm_medium=video&dgcid=RN_AG_Sourced_400004103 Important Papers covers various chemical reactions, mechanisms, and research papers in the field of organic chemistry, providing examples and explanations for each research paper. In this video, I discuss five important papers in organic synthesis that were published around June and July 2023. Make sure you share this series with other chemists in your network, especially ones who don't usually watch YouTube! I want to thank Maurice for his help with this episode :) Support the Channel on Patreon - https://www.patreon.com/thatchemist Join the Community Discord! - https://discord.gg/thatchemist Backup Discord link - https://discord.gg/QWNPETtPcZ Important Papers Playlist - https://youtube.com/playlist?list=PL6OLqxmk7RtyRkdJhXK8NWpT1krGNq1p4 ----------------------------------------- References: First Paper (Methylenecyclobutanes) - https://doi.org/10.1039/D3SC01103H Second Paper (Beraprost) - https://doi.org/10.1021/jacs.3c04582 Third Paper (TBI-223) - https://doi.org/10.1021/acs.oprd.3c00148 Fourth Paper (Mitragynine Pseudoindoxyl ) - https://doi.org/10.1002/anie.202303700 Fifth Paper (Fluoromix) - https://doi.org/10.1126/science.adi1557 (Supplemental) Periodate cleavage of 1,2-diketones - https://pubs.acs.org/doi/10.1021/ja01510a009 Hazard of NaH with DMF/DMSO - https://youtu.be/IKmMESxYLFc ----------------------------------------- Honorable mentions: Conjugated Enals - https://doi.org/10.1021/acs.orglett.3c01576 Synthesis of (+)-KB343 - https://doi.org/10.1021/jacs.3c01991 C-N Cross-Coupling - https://doi.org/10.1021/jacs.3c05627 PCSK9 Inhibitor synthesis - https://doi.org/10.1021/acs.orglett.3c01635 https://rumblevideoarchive.wordpress.com/

050623 Like and subscribe. This is an archive, check the link in the end if you are owner. This is an episode in the Extreme Chempilation series - expect mild profanity and stories that some viewers may find disturbing. In this video we have a story about TATP, which is a dangerous explosive chemical. Do not make explosives unless you know it is safe, legal and have professional training in the preparation of energetic materials. One person can threaten the lives of many people, and making explosives without taking appropriate precautions is irresponsible, dangerous, and is disrespectful to the safety and well-being of others. Summary This video discusses the dangers of making explosives without proper training and precautions. It tells a story of someone who made a large amount of TATP, a highly explosive chemical. The person shares their experiences and mistakes, including blowing up a snowman with 40 grams of TATP and making a batch using half a gallon of chemicals. The video emphasizes the extreme danger of TATP and advises against attempting such activities. Highlights 💣 Someone made large quantities of TATP, a dangerous explosive chemical. 💣 Blowing up a snowman with 40 grams of TATP. 💣 Mixing chemicals together and finding the jar boiling in the refrigerator. 💣 Pictures showing large amounts of TATP made by the person. 💣 The video warns against attempting such dangerous activities and emphasizes the extreme danger of TATP. (The 'Summary' and 'Highlights' were generated using Glarity) DO NOT EAT OR DRINK LAB CHEMICALS! 💀💀💀 I want to give a huge thanks to all the supporters of the channel on Patreon! https://www.patreon.com/thatchemist The supporters on Patreon have decided to release the Patreon chempilations! We will be gradually releasing them after they get some minor editing. These will be known as Extreme Chempilations. This was the September 2022 Patreon Chempilation, until the Patrons changed the way things work :) Join the Community Discord! - https://discord.gg/thatchemist https://rumblevideoarchive.wordpress.com/

010623 Like and subscribe. This is an archive, check the link in the end if you are owner. #standing desk #setup #flexispot Shop Flexispot standing desk here! US site: https://amzn.to/3onqlgI Canada site: https://amzn.to/43e3mDA Thanks to FlexiSpot for sponsoring this video! Placing an order using these links helps support the channel :) This is the third installment of the cursed molecules tier list series – don’t forget to drop a comment down below if you like the new 3D format! I don’t usually ask you magnificent viewers to like/subscribe/click that bell, but I guess if you don’t use the ‘Subscriptions’ tab to watch videos on YouTube, then you might not be shown when channels you are subscribed to finally upload a new video. If you want to see each and every video we upload, you can click the bell, but if you prefer to trust the algorithm, it can stay unclicked and the algorithms should show you our videos if other people (similar to you in the algorithms' eyes) enjoy the video and the algorithms think it’s a video you may enjoy watching. Support the Channel on Patreon - https://www.patreon.com/thatchemist Join the Community Discord! - https://discord.gg/thatchemist _________ *Team* Writer/Producer - That Chemist (Joey) Graphic Designer/Editor/Animator – ReformLabs (David) Chemistry Assistant - Maurice Production Assistant - Aldous (Nicholas) 3D Systems Engineer - Robot Chicken Thumbnail Artists – RinFroggy & David Ad Co-host - Teresa _________ *Music* - A huge thanks to @S3RL for letting us use his music in the video! "All That I Need - S3RL feat Kayliana & MC Riddle" Contact S3RL - https://withkoji.com/@S3RL The music in the sponsored segment is "Bonfire - An Jone" _________ Molecules for this tier list: 1,3-bisohosphoglyceric acid, Novec 7700, Alloxan, Asparagusic acid, Beclabuvir, Cycasin, Methylazoxymethanol acetate, Diminazene, Empagliflozin, Epibatidine, Falcarindiol, Feprosidnine, Mesocarb, Timolol, Hipposudoric acid _________ *References* 1,3-bisohosphoglyceric acid http://content.febsjournal.org/cgi/content/abstract/186/1/265 Novec 7700 https://www.parallax-tech.com/all3m/novec-7700.pdf Alloxan http://www.orgsyn.org/demo.aspx?prep=CV4P0023 Asparagusic acid https://dmd.aspetjournals.org/content/29/4/539.full Beclabuvir https://www.clinicaltrials.gov/show/NCT03071133 Cycasin https://doi.org/10.1177%2F104063879300500337 Methylazoxymethanol acetate https://doi.org/10.1111%2Fj.1476-5381.2011.01386.x Diminazene https://doi.org/10.1016%2F0001-706X%2893%2990092-P Empagliflozin https://www.drugs.com/monograph/empagliflozin.html Epibatidine https://doi.org/10.1021%2Fnp900727e Falcarindiol https://doi.org/10.1016%2F0048-4059%2878%2990039-5 Feprosidnine https://pubmed.ncbi.nlm.nih.gov/7449977 Mesocarb https://pubmed.ncbi.nlm.nih.gov/4825943 Timolol https://www.drugs.com/monograph/timolol-eent.html Hipposudoric acid https://doi.org/10.1351%2Fpac200779040507 If you want a clip of just the outro to loop and watch - https://youtu.be/HkdmsOJKTmE (go listen to S3RL on Spotify or wherever you listen to music! He's one of my favorite artists and I am so stoked that he is letting us use his music on the channel) https://rumblevideoarchive.wordpress.com/

030623 Like and subscribe. This is an archive, check the link in the end if you are owner. This is an episode in the Extreme Chempilation series - expect mild profanity and stories that some viewers may find disturbing. Summary This video discusses a story about someone who drank acetone, emphasizing the dangers of consuming chemicals not intended for ingestion. The person experienced unpleasant effects and shared their experiences online, promoting dangerous behavior. The video also mentions the toxicity of acetone, the potential health risks involved, and provides anecdotes about other chemical accidents and risky experiments. Highlights 💀 Someone drank 50 mL of acetone, which is highly dangerous and should not be replicated. 🧪 The person experienced unpleasant effects, including a thunderous headache and a sickeningly sweet aftertaste. 🚫 Drinking acetone is unsafe, and the individual lacked proper knowledge about its risks. 🤔 The person was driven by curiosity and the opportunity to get paid for performing dangerous experiments. 📚 Anecdotes are shared about other chemical accidents and risky behavior in laboratories. 🍌 A video is mentioned about using unripe banana water for chemical reactions, showcasing unusual experiments. (The 'Summary' and 'Highlights' were generated using Glarity) DO NOT EAT OR DRINK LAB CHEMICALS! 💀💀💀 I want to give a huge thanks to all the supporters of the channel on Patreon! https://www.patreon.com/thatchemist The supporters on Patreon have decided to release the Patreon chempilations! We will be gradually releasing them after they get some minor editing. These will be known as Extreme Chempilations. This was the August 2022 Patreon Chempilation, until the Patrons changed the way things work :) Join the Community Discord! - https://discord.gg/thatchemist https://rumblevideoarchive.wordpress.com/

250523 Like and subscribe. This is an archive, check the link in the end if you are owner. Interested in boosting success rates in synthesis route design and prediction using the Predictive Retrosynthesis Tool from Reaxys? Find out more information here - https://www.elsevier.com/solutions/reaxys/predictive-retrosynthesis?utm_campaign=prt-integration-ads&utm_source=thatchemist&utm_medium=video&dgcid=RN_AG_Sourced_400004103 Important Papers covers various chemical reactions, mechanisms, and research papers in the field of organic chemistry, providing examples and explanations for each research paper. In this video, I discuss five important papers in organic synthesis that were published around May 2023. Anticipate that we will be taking a break for June 2023. Make sure you share this series with other chemists in your network, especially ones who don't usually watch YouTube! Support the Channel on Patreon - https://www.patreon.com/thatchemist Join the Community Discord! - https://discord.gg/thatchemist Backup Discord link - https://discord.gg/QWNPETtPcZ Important Papers Playlist - https://youtube.com/playlist?list=PL6OLqxmk7RtyRkdJhXK8NWpT1krGNq1p4 ----------------------------------------- References: First Paper (Daphnillonin B) - https://pubs.acs.org/doi/pdf/10.1021/jacs.3c03755 Second Paper (Photocatalytic Denitrogenation) - https://pubs.acs.org/doi/pdf/10.1021/jacs.3c03634 Third Paper (Radical Hydrocarboxylation) - https://pubs.acs.org/doi/pdf/10.1021/jacs.3c03671 Fourth Paper (Esters to Ketones) - https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.3c00992 Fifth Paper (Skeletal Editing) - https://pubs.acs.org/doi/pdf/10.1021/jacs.3c02616 ----------------------------------------- Honorable mentions: Benzocyclobutanes (https://doi.org/10.1126/science.adg5282) Nickel-Catalyzed Catellani (https://doi.org/10.1021/jacs.3c03780) Total Syntheses of (+)-Waixenicin A (https://doi.org/10.1021/jacs.3c03366) Total Synthesis of Pentamycin (https://doi.org/10.1021/jacs.3c03011) Addition to N‑Alkyl Nicotinate Salts (https://doi.org/10.1021/jacs.3c03048) https://rumblevideoarchive.wordpress.com/

200523 Like and subscribe. This is an archive, check the link in the end if you are owner. This is an episode in the Extreme Chempilation series - expect mild profanity and stories that some viewers may find disturbing. I want to give a huge thanks to all the supporters of the channel on Patreon! https://www.patreon.com/thatchemist The supporters on Patreon have decided to release the Patreon chempilations! We will be gradually releasing them after they get some minor editing. These will be known as Extreme Chempilations. This was the May 2023 Patreon Chempilation, until the Patrons changed the way things work :) Join the Community Discord! - https://discord.gg/thatchemist https://rumblevideoarchive.wordpress.com/

130522 Like and subscribe. This is an archive, check the link in the end if you are owner. I hope you enjoyed the video! I'm planning on making a full series of videos if these videos are helpful for people! I mistakenly labeled diethyl sulfide as propanethiol. Recommended Texts: J. Clayden, N. Greeves, S. Warren, Organic Chemistry Second Edition, Oxford University Press, 2012. (especially good for mechanism and physical chemistry explanations) T. W. G. Solomons, C. B. Fryle, S. A. Snyder, Organic Chemistry Twelfth Edition, Wiley-VCH Verlag GmbH & Co. KGaA, 2016. LibreTexts: https://chem.libretexts.org/Bookshelves/Organic_Chemistry https://rumblevideoarchive.wordpress.com/

Like and subscribe. This is an archive channel, i'm not the owner of the content, check the link in the end. Interested in boosting success rates in synthesis route design and prediction using the Predictive Retrosynthesis Tool from Reaxys? Find out more information here - https://www.elsevier.com/solutions/reaxys/predictive-retrosynthesis?utm_campaign=prt-integration-ads&utm_source=thatchemist&utm_medium=video&dgcid=RN_AG_Sourced_400004103 Important Papers covers various chemical reactions, mechanisms, and research papers in the field of organic chemistry, providing examples and explanations for each research paper. In this video, I discuss five important papers in organic synthesis that were published around April 2023. Make sure you share this series with other chemists in your network, especially ones who don't usually watch YouTube! Support the Channel on Patreon - https://www.patreon.com/thatchemist Join the Community Discord! - https://discord.gg/thatchemist Backup Discord link - https://discord.gg/QWNPETtPcZ Important Papers Playlist - https://youtube.com/playlist?list=PL6OLqxmk7RtyRkdJhXK8NWpT1krGNq1p4 ----------------------------------------- References: First Paper (Diethanolamine Boronates) - https://pubs.acs.org/doi/10.1021/acs.oprd.2c00342 Second Paper (Sulfones via Sulfonyl Fluorides) - https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.3c00447 Third Paper (Deoxygenation of Alcohols) - https://doi.org/10.1002/anie.202300178 Fourth Paper (Room Temp Ar-Br Amination) - https://doi.org/10.1021/jacs.3c00500 Fifth Paper (Desymmetrization of Boronates) - https://doi.org/10.1021/jacs.3c01571 ----------------------------------------- Honorable mentions: Total Synthesis of (+)-Pedrolide - https://doi.org/10.1021/jacs.3c02113 Molybdenum(VI) Amide Activation - https://doi.org/10.1021/acs.joc.3c00218 Diastereoselective Synthesis of Cyclopropanes - https://doi.org/10.1002/ange.202303032 Tris(bicyclo[1.1.1]pentyl)phosphine - https://doi.org/10.1021/jacs.3c00885 Total Synthesis of Strempeliopidine - https://doi.org/10.1021/jacs.2c13146 Sulfonylation of Aryl Bromides - https://doi.org/10.1002/anie.202217623 Grayanane Diterpenoids - https://doi.org/10.1021/jacs.3c00753 Mechanochemical Birch - https://doi.org/10.1002/anie.202217723 Compact Rotaxane Superbases - https://doi.org/10.1021/jacs.3c01202 Dearomatization of arenes with tetrazinediones - https://doi.org/10.1021/jacs.3c02556 Enantioselective Divergent Syntheses of Cephalotaxus Alkaloids - https://doi.org/10.1021/jacs.3c01572 One-Bond-Nucleophilicity and -Electrophilicity Parameters: An Efficient Ordering System for 1,3-Dipolar Cycloadditions - https://pubs.acs.org/doi/full/10.1021/jacs.2c13872 – Mayr paper Mayr’s N-parameter Database - https://www.cup.lmu.de/oc/mayr/reaktionsdatenbank2/ Waveform-controlled Electrosynthesis - https://doi.org/10.1126/science.adf4762 https://rumblevideoarchive.wordpress.com/

Like and subscribe. This is an archive channel, i'm not the owner of the content, check the link in the end. Use code POGCHEMISTAPR50 for 50% off your first box at https://strms.net/ThatChemistFactorAprYT50 #ad -------------------------------------------------------------------------------------------- Cubanes are a pretty neat class of molecules – in this video, we explore the applications of cubanes, and rank some impressive cubanes such as BUTTERCUBE! Support the Channel on Patreon - https://www.patreon.com/thatchemist Join the Community Discord! - https://discord.gg/thatchemist _________ *Team* Writer/Producer - That Chemist (Joey) Editor/Lead Animator - ReformLabs 3D Systems Engineer - Robot Chicken Thumbnail Artist - RinFroggy _________ *Acknowledgements* Thanks to the people on Twitter who helped suggest cubane references! Especially Kitspiroplatin for the reference of the extremely long tetracubane iodide! I also want to acknowledge that Tom will eventually make cubane. _________ *References* Tom’s Cubane Series https://www.youtube.com/playlist?list=PLnafk93vhO36cccP0p83hcop3xBTYkoTN Perfluorocubane https://www.youtube.com/watch?v=Tn9EANWD96s Chemiolis Click Chem https://www.youtube.com/watch?v=Ekbqix9fKXQ Casual Chemistry Click Chem https://www.youtube.com/watch?v=RqA4xQ4ujWI Cubane Review Articles: Cubanes in Med Chem http://doi.org/10.1021/acs.jmedchem.8b00888 Cubanes: 50 Years Later http://doi.org/10.1021/cr500523x Bicubyl/extremely long cubane https://pubs.acs.org/doi/10.1021/ja983441f bidentate cubane ligand https://doi.org/10.1055/s-0029-1217083 butter cubane https://doi.org/10.1016/S0040-4039(00)73295-3 carboxycubane thioxanthylglycine - https://worldwide.espacenet.com/patent/search?q=pn%3DWO2004024709 (page 48) cubane carboxylic acid https://doi.org/10.1002/chem.201901086 cubane dicarboxylic acid dimethyl ester https://doi.org/10.1055/s-0040-1705964 cubane https://doi.org/10.1055/s-1995-3961 cubene https://doi.org/10.1021/ja00229a057 cubyl phenyl ketone https://pubs.rsc.org/en/content/articlelanding/2019/OB/C9OB01238A cubyl triflate https://pubs.acs.org/doi/abs/10.1021/ja00164a063 cubylmethanol https://doi.org/10.1021/ol501750k dideuterocubane https://pubs.acs.org/doi/10.1021/jp953432i diethynyl cubane https://pubs.acs.org/doi/abs/10.1021/ja00096a016 diflucuburon https://doi.org/10.1002/anie.201510675 letepricube https://worldwide.espacenet.com/patent/search?q=pn%3DWO2011068881 mercury cubane insanity https://doi.org/10.1021/cr500523x (compound 71) methoxycarbonylcubane carboxylic acid - 10.1002/chem.201901086 octamethylcubane https://doi.org/10.1016/S0040-4039(00)73295-3 octacyclopropylcubane https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.200605150 octanitrocubane https://doi.org/10.1002/(SICI)1521-3773(20000117)39:2%3C401::AID-ANIE401%3E3.0.CO;2-P (this DOI sucks) octaphenylcubane https://pubs.acs.org/doi/abs/10.1021/jo01058a537 perfluorocubane https://doi.org/10.1126/science.abq0516 perfluorooctamethylcubane https://pubs.acs.org/doi/abs/10.1021/ja00430a050 tetracarbomethoxycubane https://link.springer.com/article/10.1007/BF01665973 lead/tin cubane insanity/tetrabromotetranitrocubane https://pubs.acs.org/doi/10.1021/jo971308k cubane on a pedestal - https://doi.org/10.1002/anie.199214211 _________ *Molecules in this Tierlist* Bicubyl, bidentate cubane ligand, butter cubane, carboxycubane thioxanthylglycine, cubane carboxylic acid, cubane dicarboxylic acid dimethyl ester, cubane, cubene, cubyl phenyl ketone, cubyl triflate, cubylmethanol, dideuterocubane, diethynyl cubane, diflucuburon, letepricube, mercury cubane insanity, methoxycarbonylcubane carboxylic acid, octamethylcubane, octacyclopropylcubane, octanitrocubane, octaphenylcubane, perfluorocubane, perfluorooctamethylcubane, tetrabromotetranitrocubane, tetracarbomethoxycubane, tin cubane insanity, extremely long cubane, lead cubane insanity, cubane on a pedestal. https://rumblevideoarchive.wordpress.com/

Like and subscribe. This is an archive channel, i'm not the owner of the content, check the link in the end. How realistic is the chemistry in breaking bad? Is it believable? I want to thank Rinfroggy and Molotay for their contributions to this project. Molotay - find out more at rb.gy/16go look at your calendar - anything important to do today? Oh yeah - rewatch all of breaking bad just to relate to a youtube video. https://rumblevideoarchive.wordpress.com/