Leo & Longevity

Citations: Heerspink, H. J., Sjöström, C. D., Jongs, N., Chertow, G. M., Kosiborod, M., Hou, F. F., ... & Wheeler, D. C. (2021). Effects of dapagliflozin on mortality in patients with chronic kidney disease: a pre-specified analysis from the DAPA-CKD randomized controlled trial. European Heart Journal, 42(13), 1216-1227. https://academic.oup.com/eurheartj/article/42/13/1216/6207268?login=true Ding, X., Wang, X., Wu, J., Zhang, M., & Cui, M. (2021). Triglyceride–glucose index and the incidence of atherosclerotic cardiovascular diseases: a meta-analysis of cohort studies. Cardiovascular Diabetology, 20(1), 1-13. https://cardiab.biomedcentral.com/articles/10.1186/s12933-021-01268-9 Faramarzpour, M., Farhang Zand-Parsa, A., Taslimi, R., & Hoseini, M. (2021). Association between Nonalcoholic Fatty Liver Disease Based on Ultrasonography Indices and Severity of Coronary Artery Disease: A Cross-Sectional Study. Studies in Medical Sciences, 31(12), 956-964. http://umj.umsu.ac.ir/browse.php?a_id=5345&sid=1&slc_lang=en Arias, H. R., Targowska-Duda, K. M., García-Colunga, J., & Ortells, M. O. (2021). Is the Antidepressant Activity of Selective Serotonin Reuptake Inhibitors Mediated by Nicotinic Acetylcholine Receptors?. Molecules, 26(8), 2149. https://www.mdpi.com/1420-3049/26/8/2149 👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community / thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ / @luciec.7692 Kids ▶ / @bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.

The most knowledgeable man in bodybuilding returns to the show! 👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community / thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ / @luciec.7692 Kids ▶ / @bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.

In this video, I discuss the evidence about the nutritional content of organic vs. non-organic vegetables, meats, and milk. I then survey the (sparse) preliminary evidence we have of non-organic foods causing harm to humans. 👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community / thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ / @luciec.7692 Kids ▶ / @bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.

In this clip of an upcoming podcast, Tony Huge, founder of Enhanced Athlete, tells us how he developed his personal charisma, and reflects on his belief that marijuana enhances his empathy. To find Tony on Instagram, visit ▶ https://www.instagram.com/drtonyhuge 👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community / thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ / @luciec.7692 Kids ▶ / @bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.

TO READ THE BLOG POST: Blog ▶ https://www.leoandlongevity.com/post/spermatogenesis-its-regulation-and-recovery 👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community / thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ / @luciec.7692 Kids ▶ / @bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.

In this clip from next Tuesday's podcast, Vigorous Steve tells us what made him make the major life decision of leaving Holland to live as an expat in Asia. TO FOLLOW STEVE: Instagram ▶ https://www.instagram.com/vigoroussteve 👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community / thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ / @luciec.7692 Kids ▶ / @bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.

TO READ THE ACCOMPANYING BLOG POST: Blog post ▶ https://www.leoandlongevity.com/post/choline-an-integral-circadian-system 👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community / thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ / @luciec.7692 Kids ▶ / @bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.

In this video, I discuss the effect that liquid handcuffs have on the brain and hormones. 👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community / thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ / @luciec.7692 Kids ▶ / @bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.

👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community /thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ /@luciec.7692 Kids ▶ /@bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.

Citations: Liu, H., Campana, A. M., Wang, Y., Kannan, K., Liu, M., Zhu, H., ... & Ghassabian, A. (2021). Organophosphate pesticide exposure: Demographic and dietary predictors in an urban pregnancy cohort. Environmental Pollution, 116920.https://www.sciencedirect.com/science/article/abs/pii/S0269749121005029 Han, L. W., Shi, Y., Paquette, A., Wang, L., Bammler, T. K., & Mao, Q. (2021). Key hepatic metabolic pathways are altered in germ-free mice during pregnancy. PloS one, 16(3), e0248351.https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0248351 Ma, Z., Cao, X., Chang, Y., Li, W., Chen, X., & Tang, N. J. (2021). Association between gestational exposure and risk of congenital heart disease: A systematic review and meta-analysis. Environmental Research, 111014.https://www.sciencedirect.com/science/article/abs/pii/S001393512100308X Marcks, N., Aimo, A., Januzzi, J. L., Vergaro, G., Clerico, A., Latini, R., ... & Brunner-La Rocca, H. P. (2021). Re-appraisal of the obesity paradox in heart failure: a meta-analysis of individual data. Clinical Research in Cardiology, 1-12. https://link.springer.com/article/10.1007/s00392-021-01822-1 Takahara, S., Soni, S., Maayah, Z. H., Ferdaoussi, M., & Dyck, J. R. (2021). Ketone Therapy for Heart Failure: Current Evidence for Clinical Use. Cardiovascular Research.https://academic.oup.com/cardiovascres/advance-article-abstract/doi/10.1093/cvr/cvab068/6168424 👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community / thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ / @luciec.7692 Kids ▶ / @bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.

TIMESTAMPS: 00:00 Introduction 04:20 Taking Valium as a child 08:08 How K-12 education has worsened 11:00 Carnegie Mellon 15:20 Falling in love with combinatorics 23:00 Mutual friend: Professor Jonathan Caulkins 27:00 The value of a liberal arts education 34:45 Backgammon 37:00 Geography and mathematics 38:30 Von Neumann & Morgenstern: game theory 40:30 The Millennial Problems 48:10 Poker, chess, and games 49:00 Mathemagics and James Randi 52:50 James Randi's prize 54:00 Mutual rant on astrology 1:03:30 Changes in academia 👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community / thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ / @luciec.7692 Kids ▶ / @bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.

👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community /thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ /@luciec.7692 Kids ▶ /@bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.

In this clip from next Tuesday's podcast, Gregg tells us why Lou Ferrigno's father died estranged from his son. 👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community / thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ / @luciec.7692 Kids ▶ / @bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.

Citations: Lawson, K., Singh, A., Kantsedikas, I., Jenner, C. A., & Austen, D. K. (2021). Flupirtine as a Potential Treatment for Fibromyalgia. Journal of Exploratory Research in Pharmacology, (000), 0-0. https://www.xiahepublishing.com/2572-5505/JERP-2020-00043 De Sa Nogueira, D., Bourdy, R., Filliol, D., Romieu, P., & Befort, K. Hippocampal mu opioid receptors are modulated following cocaine self‐administration in rat. European Journal of Neuroscience. https://onlinelibrary.wiley.com/doi/abs/10.1111/ejn.15217 Yu, J., Ren, L., Min, S., Lv, F., Luo, J., Li, P., & Zhang, Y. (2021). Inhibition of CB1 receptor alleviates electroconvulsive shock-induced memory impairment by regulating hippocampal synaptic plasticity in depressive rats. Psychiatry Research, 113917. https://www.sciencedirect.com/science/article/abs/pii/S0165178121002146 👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community / thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ / @luciec.7692 Kids ▶ / @bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.

Citations: Jagannathan, R., Rajagopalan, K., Hogan, J., Hart, A., Newell, K. A., Pastan, S. O., & Patzer, R. E. (2021). Association Between APOL1 Genotype and Kidney Diseases and Annual Kidney Function Change: A Systematic Review and Meta-Analysis of the Prospective Studies. International Journal of Nephrology and Renovascular Disease, 14, 97-104. https://www.dovepress.com/association-between-apol1-genotype-and-kidney-diseases-and-annual-kidn-peer-reviewed-fulltext-article-IJNRD Barbagallo, C. M., Cefalù, A. B., Giammanco, A., Noto, D., Caldarella, R., Ciaccio, M., ... & Nardi, E. (2021). Lipoprotein Abnormalities in Chronic Kidney Disease and Renal Transplantation. Life, 11(4), 315. https://www.mdpi.com/2075-1729/11/4/315 Gonçalves, W. A., Ferreira, R. C., Rezende, B. M., Mahecha, G. A., Gualdron, M., de Macedo, F. H., ... & Romero, T. R. (2021). Endogenous opioid and cannabinoid systems modulate the muscle pain: a pharmacological study into the peripheral site. European Journal of Pharmacology, 174089. https://www.sciencedirect.com/science/article/abs/pii/S0014299921002429 Bray, J. J., Foster‐Davies, H., Salem, A., Hoole, A. L., Obaid, D. R., Halcox, J. P., & Stephens, J. W. (2021). Glucagon‐Like Peptide‐1 Receptor Agonists (GLP‐1RAs) improve biomarkers of inflammation and oxidative stress: A systematic review and meta‐analysis of randomised controlled trials. Diabetes, Obesity and Metabolism. https://dom-pubs.onlinelibrary.wiley.com/doi/abs/10.1111/dom.14399 Simental‐Mendía, L. E., Sánchez‐García, A., Linden‐Torres, E., & Simental‐Mendía, M. (2021). Impact of glucagon‐like peptide‐1 receptor agonists on adiponectin concentrations: a meta‐analysis of randomized controlled trials. British Journal of Clinical Pharmacology. https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bcp.14855 👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community / thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ / @luciec.7692 Kids ▶ / @bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.

Timestamps by Jax: 0:00 Intro/ Mike’s backgrounds 1:58 Are enemy analysts usually knowledgeable about martial arts?/ The difference between a real journalist and iPhone “journalists” 4:24 Professional fighter commentary vs commentary from the point of view of a normal person 6:38 Successful people becoming targets 7:54 Bodybuilders creating heat on social media 11:03 Diaz vs Lawler predictions 18:16 Hafthor vs Devon Larrat 19:25 How Duane and Mike met 20:14 Talk on names 20:50 Duane on changes in Colorado over the past few decades 22:45 Professional fighters and controlled tempers 22:38 MMA and Colorado 25:13 Elevation training 26:50 Top fight gyms in Colorado Elevation fight team, Factory X, Trevor Wittman 28:55 Duane’s advice for younger fighters and genetic limitation 31:20 Focus on strengths rather than weaknesses 32:16 Different kickboxing federations 33:34 Effects of UFC on kickboxing 34:33 Dutch and French kickboxing 35:14 Why was BJJ so effective in early MMA and how did it transition to wrestling and boxing 37:52 Differences between western boxing and Muay Thai boxing 39:09 Where did clinching in MMA come from? 40:17 Karate and Okinawa 40:44 Gi vs no Gi BJJ 43:18 Training your kids for combat sports 44:16 Duane on Bas Rutten 45:55 “Chunking” 46:10 How do fight clubs get reimbursed for fighters? 49:17 What does Duane love doing the most? 51:25 What distinguishes Bang Muay Thai from other Muay Thai gyms 54:00 Do champions usually respond well to harsh teachers? 54:56 How does Duane help prepare for a fight? 56:22 Is coaching a lightweight different from coaching a heavyweight? 56:46 Strength training and punch speed 58:13 Pointing out what athletes are good at 58:59 Does Duane design diets for his athletes?/ Why Mike does what he does 1:03:16 You must love what you are doing to be excellent 1:03:31 How Mike’s diet works/ Micronutrients 1:05:54 Short and long term goals/ Having a consistent diet 1:08:01 Ideal body weights for weight classes 1:09:52 Chronic illness and body fat percentages/ Body fat and injury frequency 1:13:03 The importance of quality of life 1:15:00 Brown fat vs white fat 1:15:46 The importance of self-mastery 1:17:59 protecting yourself from concussions/ Beta-blockers, cerebrolysin, sodium valproate 1:21:12 Is doping common in the modern UFC?/ Chemists on staff 1:24:36 Nutritional IVs/ Choline and L carnitine IVs 1:25:25 Breaking noses while fighting 1:26:42 Duane’s coke story 1:28:26 Cauliflower ear 👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community / thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ / @luciec.7692 Kids ▶ / @bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.

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👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community /thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ /@luciec.7692 Kids ▶ /@bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.

👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community /thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ /@luciec.7692 Kids ▶ /@bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.

👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community / thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ / @luciec.7692 Kids ▶ / @bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations. Citations: Preterm birth and low birth weight after assisted reproductive technology-related pregnancy in Australia between 1996 and 2000. Fertility and sterility, 83(6), 1650-1658. https://www.sciencedirect.com/science/article/abs/pii/S0015028205003869 Assisted reproductive technology and major birth defects in Western Australia. Obstetrics & Gynecology, 120(4), 852-863. https://journals.lww.com/greenjournal/FullText/2012/10000/Assisted_Reproductive_Technology_and_Major_Birth.17.aspx Low and very low birth weight in infants conceived with use of assisted reproductive technology. New England Journal of Medicine, 346(10), 731-737. https://www.nejm.org/doi/full/10.1056/NEJMoa010806 Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies. Bmj, 328(7434), 261. https://www.bmj.com/content/328/7434/261?ecoll= Obstetric and perinatal outcomes in singleton pregnancies resulting from IVF/ICSI: a systematic review and meta-analysis. Human reproduction update, 18(5), 485-503. https://academic.oup.com/humupd/article-abstract/18/5/485/599029 The effect of various infertility treatments on the risk of preterm birth. Human reproduction, 17(4), 945-949. https://academic.oup.com/humrep/article-abstract/17/4/945/644624 Adverse outcomes of IVF/ICSI pregnancies vary depending on aetiology of infertility. International Scholarly Research Notices, 2012. https://downloads.hindawi.com/archive/2012/451915.pdf Perinatal outcomes by mode of assisted conception and sub-fertility in an Australian data linkage cohort. PloS one, 9(1), e80398. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080398 Perinatal outcomes associated with assisted reproductive technology: the Massachusetts Outcomes Study of Assisted Reproductive Technologies (MOSART). Fertility and sterility, 103(4), 888-895. https://www.sciencedirect.com/science/article/abs/pii/S0015028214025503 Pregnancy-related complications and adverse pregnancy outcomes in multiple pregnancies resulting from assisted reproductive technology: a meta-analysis of cohort studies. Fertility and sterility, 103(6), 1492-1508. https://www.sciencedirect.com/science/article/abs/pii/S001502821500223X Maternal and child-health outcomes in pregnancies following Assisted Reproductive Technology (ART): a prospective cohort study. BMC pregnancy and childbirth, 20(1), 1-8. https://bmcpregnancychildbirth.biomedcentral.com/articles/10.1186/s12884-020-2755-z Cognitive development of singletons born after intracytoplasmic sperm injection compared with in vitro fertilization and natural conception. Fertility and sterility, 90(2), 289-296. https://pubmed.ncbi.nlm.nih.gov/17980875/ Assisted reproductive technology and risk for autism spectrum disorder. Research in developmental disabilities, 32(6), 2950-2956. https://www.sciencedirect.com/science/article/abs/pii/S0891422211001661 Is there an increased risk for drug treated attention deficit/hyperactivity disorder in children born after in vitro fertilization?. European journal of paediatric neurology, 15(3), 247-253. https://www.sciencedirect.com/science/article/abs/pii/S1090379810002187$ Cardiometabolic differences in children born after in vitro fertilization: follow-up study. The Journal of Clinical Endocrinology & Metabolism, 93(5), 1682-1688. https://academic.oup.com/jcem/article-abstract/93/5/1682/2598521 Absence of insulin resistance and low-grade inflammation despite early metabolic syndrome manifestations in children born after in vitro fertilization. Fertility and sterility, 94(5), 1693-1699. https://www.sciencedirect.com/science/article/abs/pii/S0015028209037996 #ivf #fertility

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Join us in this enlightening conversation with Dr. Newton Howard, a renowned figure in the realms of brain science and cognitive enhancement. From his early days to his groundbreaking work in neuroscience, Dr. Howard shares his journey, insights, and innovative technologies shaping the future of brain health. Please comment on your questions below, as he agreed to return for a longer deep dive into the brain. 👉🏻Dr. Howard's websites Brain Clinics: https://www.newtonhowardbrainclinics.com Kiwi Brain Chip: https://ni2o.com Brain Foundation: https://brainsciences.org Personal Website: https://newtonhoward.com 🏷️ Discover Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 👉🏻 More ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh - Nurosym: https://nurosym.com Discount Code: LucieC5 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community https://www.reddit.com/r/TheLongLived/ Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ https://www.youtube.com/@luciec.7692 Kids ▶ https://www.youtube.com/@bilinguini 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations. 00:00 - Introduction 02:41 - Dr. Howard's Illustrious Background 03:20 - Journey into Neuroscience 09:30 - Exploring TMS & tDCS Technologies 15:30 - Non-Surgical Approaches to Neurological Disorders 20:20 - Enhancing Brain and Cognitive Functions 25:00 - Deep Dive: TMS Mechanisms and Applications 29:30 - Dr. Howard's Vision for the Future and Legacy #neuroscience #brainhealth #cognitiveenhancement #brain

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In this clip from an upcoming podcast, Taeian Clark, a former moderator at the GH15 forums, confirms that GH15 was not Nasser Elsonbaty. 👉🏻 Ways to support and save (affiliate links): - LA Pump: https://lapump.com/?wpam_id=13 Get 10% OFF with code LONGLEO - Nurosym: https://nurosym.com Discount Code: LucieC5 -CosmicNootropic: https://cosmicnootropic.com?coupon-code=319 Get 10% OFF with code LUCIE - Amazon Store: Shop items Leo personally recommended and used https://www.amazon.com/shop/leoandlongevity?ref=ac_inf_tb_vh 🔗 Connect & Explore 🔗 JOIN THE COMMUNITY: Reddit ▶ The Long-Lived Community / thelonglived Telegram ▶ https://t.me/+k4x31DY9tgIwM2Fh TikTok ▶ https://www.tiktok.com/@leoandlongevity?_t=8hXP1SML0LG&_r=1 GENETIC ANALYSIS WAITLIST: Website ▶ https://www.yourgenetically.com/ OTHER CHANNELS Lucie ▶ / @luciec.7692 Kids ▶ / @bilinguini 🏷️ Leo's personal book collection now on eBay: https://www.ebay.com/usr/colous7 🌍 Together, Let’s Continue Leo's Legacy In the spirit of Leo's passion for health, wellness, and a life well-lived, let’s continue to explore, learn, and journey through the fascinating world of biohacking, fitness, and cognitive wellness. Your presence here is not just a subscription; it's a torchbearer of Leo's legacy, ensuring his light continues to shine, guide, and inspire future generations.