Long Story Short Episode 80: New Yale Study Shows Vaccine Injured Are Highly Symptomatic with Poor Health (Preprint)
Researchers from Yale have gathered and analyzed the types and intensity of symptoms, demography, treatment options, and psychological status of post-vaccine injured patients in a new online, observational, self-reported study. Let’s review.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
References (Nov. 16, 2023):
Post-Vaccination Syndrome: A Descriptive Analysis of Reported Symptoms and Patient Experiences After Covid-19 Immunization | medRxiv
https://www.medrxiv.org/content/10.1101/2023.11.09.23298266v1
Brianne Dressen Discusses Vaccine Caused Neurological Injuries - First NIH Study (Vaccine Injury) - YouTube
https://www.youtube.com/watch?v=9XGpe6MTaFg
NIH/NIND Vaccine Injury Study Participant Interview (Dr. Danice Hertz) - YouTube
https://www.youtube.com/watch?v=Bvssp9uA72A
Shaun Barcavage | Patient Interview - Neurological Issues After Vaccination - YouTube
https://www.youtube.com/watch?v=SobqUw7gqhs
Shaun Barcavage | Follow-up Patient Interview - Neurological Issues After Vaccination - YouTube
https://www.youtube.com/watch?v=rX8I5-yG05g
Shaun Barcavage | Third Patient Interview - Neurological Issues After Vaccination - YouTube
https://www.youtube.com/watch?v=TCkqz3kzf4s
Home - React19
https://react19.org/
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 54: Berberine Treats Atherosclerosis via a Vitamin Like Effect
Berberine Treats Atherosclerosis in Humans (Small Study)
In this amazing study the researchers demonstrate how berberine was able to reduce atherosclerotic plaque when administered for 4 months. Let's review.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
References (April 20, 2023):
Berberine treats atherosclerosis via a vitamine-like effect down-regulating Choline-TMA-TMAO production pathway in gut microbiota | Signal Transduction and Targeted Therapy
https://www.nature.com/articles/s41392-022-01027-6#ethics
Shimadzu (China) Co., Ltd. Exhibited at the China International Import Expo | SHIMADZU TODAY | SHIMADZU CORPORATION
https://www.shimadzu.com/today/20211220-1.html
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 53: Hyperinsulinemia - Cause or Consequence
In this amazing lecture Dr. Barbara E. Corkey presents the paradigm of hyperinsulenemia leading to insulin resistance, which in turn contributes to diabetes mellitus and obesity. Let's review this Banting awarded lecture.
Banting Lecture 2011 | Diabetes | American Diabetes Association
https://diabetesjournals.org/diabetes/article/61/1/4/15978/Banting-Lecture-2011Hyperinsulinemia-Cause-or
Dr. Been: www.drbeen.com
FLCCC: www.flccc.net
URL list Monday, Apr. 10, 2023
Frederick Banting - Wikipedia
https://en.wikipedia.org/wiki/Frederick_Banting
Barbara Corkey | Chobanian & Avedisian School of Medicine
https://www.bumc.bu.edu/busm/profile/barbara-corkey/
Banting Lecture 2011 | Diabetes | American Diabetes Association
https://diabetesjournals.org/diabetes/article/61/1/4/15978/Banting-Lecture-2011Hyperinsulinemia-Cause-or
Insulin Resistance & Prediabetes - NIDDK
https://www.niddk.nih.gov/health-information/diabetes/overview/what-is-diabetes/prediabetes-insulin-resistance
Banting Lecture 2011 | Diabetes | American Diabetes Association
https://diabetesjournals.org/diabetes/article/61/1/4/15978/Banting-Lecture-2011Hyperinsulinemia-Cause-or
Bariatric Surgery for Type 2 Diabetes Reversal: The Risks | Diabetes Care | American Diabetes Association
https://diabetesjournals.org/care/article/34/Supplement_2/S361/28238/Bariatric-Surgery-for-Type-2-Diabetes-Reversal-The
Bariatric Surgery to Treat Type 2 Diabetes
https://my.clevelandclinic.org/health/treatments/21153-bariatric-weight-loss-surgery-for-treating-diabetes
Nutrition Therapy for Adults With Diabetes or Prediabetes: A Consensus Report | Diabetes Care | American Diabetes Association
https://diabetesjournals.org/care/article/42/5/731/40480/Nutrition-Therapy-for-Adults-With-Diabetes-or
International Experts Outline Diabetes Remission Diagnosis Criteria | ADA
https://diabetes.org/newsroom/press-releases/2021/international-experts-outline-diabetes-remission-diagnosis-criteria
Nutritional basis of type 2 diabetes remission | The BMJ
https://www.bmj.com/content/374/bmj.n1449
Therapeutic use of intermittent fasting for people with type 2 diabetes as an alternative to insulin - PubMed
https://pubmed.ncbi.nlm.nih.gov/30301822/
Case Report: Therapeutic use of intermittent fasting for people with type 2 diabetes as an alternative to insulin - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194375/
Insights from a general practice service evaluation supporting a lower carbohydrate diet in patients with type 2 diabetes mellitus and prediabetes: a secondary analysis of routine clinic data including HbA1c, weight and prescribing over 6 years - PubMed
https://pubmed.ncbi.nlm.nih.gov/33521540/
HbA1c Calculator - HbA1c
https://www.hba1cnet.com/hba1c-calculator/
Insights from a general practice service evaluation supporting a lower carbohydrate diet in patients with type 2 diabetes mellitus and prediabetes: a secondary analysis of routine clinic data including HbA1c, weight and prescribing over 6 years - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841829/
Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial - PubMed
https://pubmed.ncbi.nlm.nih.gov/29221645/
Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial - CORE Reader
https://core.ac.uk/reader/196576423
(19) Reversing Type 2 Diabetes | Jason Fung - YouTube
https://www.youtube.com/watch?v=6KS7M0s2fJM
NIH study finds heavily processed foods cause overeating and weight gain | National Institutes of Health (NIH)
https://www.nih.gov/news-events/news-releases/nih-study-finds-heavily-processed-foods-cause-overeating-weight-gain
Resting energy expenditure in short-term starvation is increased as a result of an increase in serum norepinephrine | The American Journal of Clinical Nutrition | Oxford Academic
https://academic.oup.com/ajcn/article/71/6/1511/4729485?login=false
Alternate-day fasting in nonobese subjects: effects on body weight, body composition, and energy metabolism1,2 - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S000291652327495X?via%3Dihub
Glutathione prevents chronic oscillating glucose intake-induced β-cell dedifferentiation and failure | Cell Death & Disease
https://www.nature.com/articles/s41419-019-1552-y
The Antioxidant N-Acetylcysteine Does Not Improve Glucose Tolerance or β-Cell Function in Type 2 Diabetes - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834245/
N-Acetyl Cysteine improves the diabetic cardiac function: possible role of fibrosis inhibition | BMC Cardiovascular Disorders | Full Text
https://bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-015-0076-3
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
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Long Story Short Episode 52: Epstein Barr Virus (EBV) Reactivation in Long COVID
Your long COVID symptoms may be due to the latent virus reactivation, especially Epstein Barr Virus (EBV) reactivation. Let's review some studies.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
URL list from Thursday, Apr. 6 2023
Stress-Induced Epstein-Barr Virus Reactivation - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8470332/#:~:text=Overview%20of%20EBV%20Reactivation%20and%20the%20Lytic%20Cycle,%2C%20and%20late%20%5B56%5D.
The prevalence and long-term health effects of Long Covid among hospitalised and non-hospitalised populations: a systematic review and meta-analysis - eClinicalMedicine
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(22)00491-6/fulltext
Investigation of Long COVID Prevalence and Its Relationship to Epstein-Barr Virus Reactivation - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233978/
Positive Epstein–Barr virus detection in coronavirus disease 2019 (COVID-19) patients | Scientific Reports
https://www.nature.com/articles/s41598-021-90351-y
Frontiers | Saliva antibody-fingerprint of reactivated latent viruses after mild/asymptomatic COVID-19 is unique in patients with myalgic-encephalomyelitis/chronic fatigue syndrome
https://www.frontiersin.org/articles/10.3389/fimmu.2022.949787/full
JCI - Chronic viral coinfections differentially affect the likelihood of developing long COVID
https://www.jci.org/articles/view/163669
COVID isn't just infecting you—it could be reactivating viruses that have been dormant in your body for years | Fortune Well
https://fortune.com/well/2022/12/26/is-long-covid-chronic-fatigue-syndrome-myalgic-encephalomyelitis/
SARS-CoV-2 infection triggers reactivation of latent viruses in people with chronic fatigue syndrome
https://www.news-medical.net/news/20221116/SARS-CoV-2-infection-triggers-reactivation-of-latent-viruses-in-people-with-chronic-fatigue-syndrome.aspx
Impact of Pre-Existing Chronic Viral Infection and Reactivation on the Development of Long COVID - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327632/
Long COVID: major findings, mechanisms and recommendations | Nature Reviews Microbiology
https://www.nature.com/articles/s41579-022-00846-2
Impact of Pre-Existing Chronic Viral Infection and Reactivation on the Development of Long COVID | medRxiv
https://www.medrxiv.org/content/10.1101/2022.06.21.22276660v2
What Have We Learned about Long COVID? | Columbia University Irving Medical Center
https://www.cuimc.columbia.edu/news/what-have-we-learned-about-long-covid
Donate to the Front Line Covid-19 Critical Care Alliance, Inc.
https://frontlinecovid-19criticalcarealliance.salsalabs.org/donate/index.html
Subscribe to our mailing list on our website:
http://flccc.net/signup
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 51: Alcohol, Chronic Stress, and Brain Health
Chronic stress and a high amount of alcohol consumption can cause disruption of the glymphatic system of the brain. This disruption can in turn lead to progression of Alzheimer's Disease and deterioration of other executive functions of the brain. Let's review the last instalment of this series.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
URL list from Monday, Mar. 23 2023
The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698404/
Donate to the Front Line Covid-19 Critical Care Alliance, Inc.

To educate medical professionals and the public in safe and effective ways to prevent and treat COVID-19. Click here to make a donation:
https://frontlinecovid-19criticalcarealliance.salsalabs.org/donate/index.html
Buy FLCCC gear:
https://supportflccc.store/
Subscribe to our mailing list on our website:
http://flccc.net/signup
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 50: Omega-3 and Exercise for Brain Health
Continuing with our series about brain health and lifestyle choices, today we will discuss omega-3 fish oil and exercise. Omega-3 fish oil or omega-3 polyunsaturated fatty acids (n3-PUFA) have a rich presence in our brain tissue. n3-PUFA helps keep astrocyte from becoming activated. Hence, it reduces inflammation in the brain and also keeps aquaporin 4 (AQP4) channels polarized and on the foot processes of the astrocytes. The result is a better glymphatic flow, which washes away more beta amyloids and helps protect or stall the progress of dementia.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
URL list from Monday, Mar. 23 2023
The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698404/
Sleep well — and reduce your risk of dementia and death - Harvard Health
https://www.health.harvard.edu/blog/sleep-well-and-reduce-your-risk-of-dementia-and-death-2021050322508
APOE ε4, Alzheimer’s disease neuropathology and sleep disturbance, in individuals with and without dementia | Alzheimer's Research & Therapy | Full Text
https://alzres.biomedcentral.com/articles/10.1186/s13195-022-00992-y
N3 Phase of Sleep.
https://chat.openai.com/chat
Understanding Delta Brain Waves And Sleep
https://www.sixstepstosleep.com/understanding-delta-brain-waves/
N3: Slow Wave Sleep | Sleepopolis
https://sleepopolis.com/education/n3-slow-wave-sleep/
Stage N3 of sleep. Delta waves on EEG recordings are observed. | Download Scientific Diagram
https://www.researchgate.net/figure/Stage-N3-of-sleep-Delta-waves-on-EEG-recordings-are-observed_fig4_280558638
A 30-second Epoch consisting of the parameters of staging sleep... | Download Scientific Diagram
https://www.researchgate.net/figure/4-A-30-second-Epoch-consisting-of-the-parameters-of-staging-sleep-electroencephalogram_fig4_282014972
Hallmark of Stage N3 (slow-wave sleep or Stages 3 and 4 sleep: delta... | Download Scientific Diagram
https://www.researchgate.net/figure/Hallmark-of-Stage-N3-slow-wave-sleep-or-Stages-3-and-4-sleep-delta-waves_fig1_5812861
Frontiers | Perivascular Spaces, Glymphatic System and MR
https://www.frontiersin.org/articles/10.3389/fneur.2022.844938/full
Perivascular spaces and brain waste clearance systems: relevance for neurodegenerative and cerebrovascular pathology | SpringerLink
https://link.springer.com/article/10.1007/s00234-021-02718-7
Frontiers | Perivascular Unit: This Must Be the Place. The Anatomical Crossroad Between the Immune, Vascular and Nervous System
https://www.frontiersin.org/articles/10.3389/fnana.2020.00017/full
Neuroglia Lab : Glymphatics and virchow-robin space
http://visnu528.blogspot.com/2014/09/glymphatics-and-virchow-robin-space.html
Physiology and Clinical Relevance of Enlarged Perivascular Spaces in the Aging Brain | Neurology
https://n.neurology.org/content/98/3/107
Aquaporin-4 - Wikipedia
https://en.wikipedia.org/wiki/Aquaporin-4
Astrocyte - Wikipedia
https://en.wikipedia.org/wiki/Astrocyte
Neurocytology-Astrocytes
https://neuropathology-web.org/chapter1/chapter1bAstrocytes.html#:~:text=Astrocytic%20foot%20processes%20surround%20brain,maintains%20homeostasis%20in%20the%20CNS.
Blood-brain barrier | RIT
https://www.rit.edu/spotlights/blood-brain-barrier
The Blood-Brain Barrier | Morphology of Nervous System
https://sisu.ut.ee/histology/blood-brain-barrier
Elimination of substances from the brain parenchyma: efflux via perivascular pathways and via the blood–brain barrier | Fluids and Barriers of the CNS | Full Text
https://fluidsbarrierscns.biomedcentral.com/articles/10.1186/s12987-018-0113-6
The glymphatic systems in the brain and the eye export fluid and... | Download Scientific Diagram
https://www.researchgate.net/figure/The-glymphatic-systems-in-the-brain-and-the-eye-export-fluid-and-solutes-from_fig1_353240231
External Carotid Artery: Anatomy & Branches | Study.com
https://study.com/academy/lesson/external-carotid-artery-anatomy-branches.html
Cervical Node Mets fron Occult Primary
http://www.aboutcancer.com/cervical_node_occult_utd_907.htm
Donate to the Front Line Covid-19 Critical Care Alliance, Inc.
https://frontlinecovid-19criticalcarealliance.salsalabs.org/donate/index.html
Buy FLCCC gear:
https://supportflccc.store/
Subscribe to our mailing list on our website:
http://flccc.net/signup
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 49: Norepinephrine, Glymphatic System, and Brain Health
During the wakeful hours, the production of norepinephrine increases. This increase helps with alertness, but also causes vasoconstriction. The outcome is a reduction in the interstitial fluid levels and reduction in the clearance of waste products. During sleep, NE levels reduce, reversing the above mentioned mechanisms, leading to more interstitial fluid movement and more glymphatic clearance of the waste products and better brain health.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
URL list from Monday, Feb. 20 2023
The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698404/
Norepinephrine: What It Is, Function, Deficiency & Side Effects
https://my.clevelandclinic.org/health/articles/22610-norepinephrine-noradrenaline#:~:text=What%20does%20norepinephrine%20do%20in,pressure%20in%20times%20of%20stress.
Frontiers | Locus Coeruleus Norepinephrine in Learned Behavior: Anatomical Modularity and Spatiotemporal Integration in Targets
https://www.frontiersin.org/articles/10.3389/fncir.2021.638007/full#:~:text=The%20locus%20coeruleus%20(LC)%2C,%2C%20cerebellum%2C%20and%20spinal%20cord.
fncir-15-638007-g001.jpg (1700×984)
https://www.frontiersin.org/files/Articles/638007/fncir-15-638007-HTML/image_m/fncir-15-638007-g001.jpg
Sleep well — and reduce your risk of dementia and death - Harvard Health
https://www.health.harvard.edu/blog/sleep-well-and-reduce-your-risk-of-dementia-and-death-2021050322508
APOE ε4, Alzheimer’s disease neuropathology and sleep disturbance, in individuals with and without dementia | Alzheimer's Research & Therapy | Full Text
https://alzres.biomedcentral.com/articles/10.1186/s13195-022-00992-y
N3 Phase of Sleep.
https://chat.openai.com/chat
Understanding Delta Brain Waves And Sleep
https://www.sixstepstosleep.com/understanding-delta-brain-waves/
N3: Slow Wave Sleep | Sleepopolis
https://sleepopolis.com/education/n3-slow-wave-sleep/
Stage N3 of sleep. Delta waves on EEG recordings are observed. | Download Scientific Diagram
https://www.researchgate.net/figure/Stage-N3-of-sleep-Delta-waves-on-EEG-recordings-are-observed_fig4_280558638
A 30-second Epoch consisting of the parameters of staging sleep... | Download Scientific Diagram
https://www.researchgate.net/figure/4-A-30-second-Epoch-consisting-of-the-parameters-of-staging-sleep-electroencephalogram_fig4_282014972
Hallmark of Stage N3 (slow-wave sleep or Stages 3 and 4 sleep: delta... | Download Scientific Diagram
https://www.researchgate.net/figure/Hallmark-of-Stage-N3-slow-wave-sleep-or-Stages-3-and-4-sleep-delta-waves_fig1_5812861
Frontiers | Perivascular Spaces, Glymphatic System and MR
https://www.frontiersin.org/articles/10.3389/fneur.2022.844938/full
Perivascular spaces and brain waste clearance systems: relevance for neurodegenerative and cerebrovascular pathology | SpringerLink
https://link.springer.com/article/10.1007/s00234-021-02718-7
Frontiers | Perivascular Unit: This Must Be the Place. The Anatomical Crossroad Between the Immune, Vascular and Nervous System
https://www.frontiersin.org/articles/10.3389/fnana.2020.00017/full
Neuroglia Lab : Glymphatics and virchow-robin space
http://visnu528.blogspot.com/2014/09/glymphatics-and-virchow-robin-space.html
Physiology and Clinical Relevance of Enlarged Perivascular Spaces in the Aging Brain | Neurology
https://n.neurology.org/content/98/3/107
Aquaporin-4 - Wikipedia
https://en.wikipedia.org/wiki/Aquaporin-4
Astrocyte - Wikipedia
https://en.wikipedia.org/wiki/Astrocyte
Neurocytology-Astrocytes
https://neuropathology-web.org/chapter1/chapter1bAstrocytes.html#:~:text=Astrocytic%20foot%20processes%20surround%20brain,maintains%20homeostasis%20in%20the%20CNS.
Blood-brain barrier | RIT
https://www.rit.edu/spotlights/blood-brain-barrier
The Blood-Brain Barrier | Morphology of Nervous System
https://sisu.ut.ee/histology/blood-brain-barrier
Elimination of substances from the brain parenchyma: efflux via perivascular pathways and via the blood–brain barrier | Fluids and Barriers of the CNS | Full Text
https://fluidsbarrierscns.biomedcentral.com/articles/10.1186/s12987-018-0113-6
The glymphatic systems in the brain and the eye export fluid and... | Download Scientific Diagram
https://www.researchgate.net/figure/The-glymphatic-systems-in-the-brain-and-the-eye-export-fluid-and-solutes-from_fig1_353240231
External Carotid Artery: Anatomy & Branches | Study.com
https://study.com/academy/lesson/external-carotid-artery-anatomy-branches.html
Cervical Node Mets fron Occult Primary
http://www.aboutcancer.com/cervical_node_occult_utd_907.htm
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
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Long Story Short Episode 48: Alzheimer's, Sleep Disturbance, and Brain Health
Studies present an association between APOE4 and sleep disturbance. Additionally APOE4 is linked to sleep disturbance before the onset of Alzheimer's symptoms. In ‘The Sleeping Brain’ article (see below) the authors suggest that sleep disturbance causes reduced removal of the waste products from the brain, leading to the accumulation of beta amyloids - which in turn is observed in Alzheimer's disease. Additionally, it is thought that APOE directly leads to beta amyloid metabolism disturbance. And, finally, it is thought that stress-related proteolytic cleavage of APOE4 leads to accumulation of tau proteins. Let's review the evidence.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
URL list from Monday, Feb. 20 2023
The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698404/
Sleep well — and reduce your risk of dementia and death - Harvard Health
https://www.health.harvard.edu/blog/sleep-well-and-reduce-your-risk-of-dementia-and-death-2021050322508
APOE ε4, Alzheimer’s disease neuropathology and sleep disturbance, in individuals with and without dementia | Alzheimer's Research & Therapy | Full Text
https://alzres.biomedcentral.com/articles/10.1186/s13195-022-00992-y
N3 Phase of Sleep.
https://chat.openai.com/chat
Understanding Delta Brain Waves And Sleep
https://www.sixstepstosleep.com/understanding-delta-brain-waves/
N3: Slow Wave Sleep | Sleepopolis
https://sleepopolis.com/education/n3-slow-wave-sleep/
Stage N3 of sleep. Delta waves on EEG recordings are observed. | Download Scientific Diagram
https://www.researchgate.net/figure/Stage-N3-of-sleep-Delta-waves-on-EEG-recordings-are-observed_fig4_280558638
A 30-second Epoch consisting of the parameters of staging sleep... | Download Scientific Diagram
https://www.researchgate.net/figure/4-A-30-second-Epoch-consisting-of-the-parameters-of-staging-sleep-electroencephalogram_fig4_282014972
Hallmark of Stage N3 (slow-wave sleep or Stages 3 and 4 sleep: delta... | Download Scientific Diagram
https://www.researchgate.net/figure/Hallmark-of-Stage-N3-slow-wave-sleep-or-Stages-3-and-4-sleep-delta-waves_fig1_5812861
Frontiers | Perivascular Spaces, Glymphatic System and MR
https://www.frontiersin.org/articles/10.3389/fneur.2022.844938/full
Perivascular spaces and brain waste clearance systems: relevance for neurodegenerative and cerebrovascular pathology | SpringerLink
https://link.springer.com/article/10.1007/s00234-021-02718-7
Frontiers | Perivascular Unit: This Must Be the Place. The Anatomical Crossroad Between the Immune, Vascular and Nervous System
https://www.frontiersin.org/articles/10.3389/fnana.2020.00017/full
Neuroglia Lab : Glymphatics and virchow-robin space
http://visnu528.blogspot.com/2014/09/glymphatics-and-virchow-robin-space.html
Physiology and Clinical Relevance of Enlarged Perivascular Spaces in the Aging Brain | Neurology
https://n.neurology.org/content/98/3/107
Aquaporin-4 - Wikipedia
https://en.wikipedia.org/wiki/Aquaporin-4
Astrocyte - Wikipedia
https://en.wikipedia.org/wiki/Astrocyte
Neurocytology-Astrocytes
https://neuropathology-web.org/chapter1/chapter1bAstrocytes.html#:~:text=Astrocytic%20foot%20processes%20surround%20brain,maintains%20homeostasis%20in%20the%20CNS.
Blood-brain barrier | RIT
https://www.rit.edu/spotlights/blood-brain-barrier
The Blood-Brain Barrier | Morphology of Nervous System
https://sisu.ut.ee/histology/blood-brain-barrier
Elimination of substances from the brain parenchyma: efflux via perivascular pathways and via the blood–brain barrier | Fluids and Barriers of the CNS | Full Text
https://fluidsbarrierscns.biomedcentral.com/articles/10.1186/s12987-018-0113-6
The glymphatic systems in the brain and the eye export fluid and... | Download Scientific Diagram
https://www.researchgate.net/figure/The-glymphatic-systems-in-the-brain-and-the-eye-export-fluid-and-solutes-from_fig1_353240231
External Carotid Artery: Anatomy & Branches | Study.com
https://study.com/academy/lesson/external-carotid-artery-anatomy-branches.html
Cervical Node Mets fron Occult Primary
http://www.aboutcancer.com/cervical_node_occult_utd_907.htm
Donate to the Front Line Covid-19 Critical Care Alliance, Inc.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 47: Role of The Glymphatic System in Sleep and Brain Health
N3 Sleep, Glymphatic System, and Brain Health
N3 phase of the sleep is characterised by delta waves, also called slow wave sleep (SWS). This is the most restorative phase of the sleep. An important part of this phase is the increase in the glymphatic convection in the brain leading to clearance of the waste products. Let's review.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
URL list from Monday, Feb. 20 2023
The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698404/
N3 Phase of Sleep.
https://chat.openai.com/chat
Understanding Delta Brain Waves And Sleep
https://www.sixstepstosleep.com/understanding-delta-brain-waves/
N3: Slow Wave Sleep | Sleepopolis
https://sleepopolis.com/education/n3-slow-wave-sleep/
Stage N3 of sleep. Delta waves on EEG recordings are observed. | Download Scientific Diagram
https://www.researchgate.net/figure/Stage-N3-of-sleep-Delta-waves-on-EEG-recordings-are-observed_fig4_280558638
A 30-second Epoch consisting of the parameters of staging sleep... | Download Scientific Diagram
https://www.researchgate.net/figure/4-A-30-second-Epoch-consisting-of-the-parameters-of-staging-sleep-electroencephalogram_fig4_282014972
Hallmark of Stage N3 (slow-wave sleep or Stages 3 and 4 sleep: delta... | Download Scientific Diagram
https://www.researchgate.net/figure/Hallmark-of-Stage-N3-slow-wave-sleep-or-Stages-3-and-4-sleep-delta-waves_fig1_5812861
Frontiers | Perivascular Spaces, Glymphatic System and MR
https://www.frontiersin.org/articles/10.3389/fneur.2022.844938/full
Perivascular spaces and brain waste clearance systems: relevance for neurodegenerative and cerebrovascular pathology | SpringerLink
https://link.springer.com/article/10.1007/s00234-021-02718-7
Frontiers | Perivascular Unit: This Must Be the Place. The Anatomical Crossroad Between the Immune, Vascular and Nervous System
https://www.frontiersin.org/articles/10.3389/fnana.2020.00017/full
Neuroglia Lab : Glymphatics and virchow-robin space
http://visnu528.blogspot.com/2014/09/glymphatics-and-virchow-robin-space.html
Physiology and Clinical Relevance of Enlarged Perivascular Spaces in the Aging Brain | Neurology
https://n.neurology.org/content/98/3/107
Aquaporin-4 - Wikipedia
https://en.wikipedia.org/wiki/Aquaporin-4
Astrocyte - Wikipedia
https://en.wikipedia.org/wiki/Astrocyte
Neurocytology-Astrocytes
https://neuropathology-web.org/chapter1/chapter1bAstrocytes.html#:~:text=Astrocytic%20foot%20processes%20surround%20brain,maintains%20homeostasis%20in%20the%20CNS.
Blood-brain barrier | RIT
https://www.rit.edu/spotlights/blood-brain-barrier
The Blood-Brain Barrier | Morphology of Nervous System
https://sisu.ut.ee/histology/blood-brain-barrier
Elimination of substances from the brain parenchyma: efflux via perivascular pathways and via the blood–brain barrier | Fluids and Barriers of the CNS | Full Text
https://fluidsbarrierscns.biomedcentral.com/articles/10.1186/s12987-018-0113-6
The glymphatic systems in the brain and the eye export fluid and... | Download Scientific Diagram
https://www.researchgate.net/figure/The-glymphatic-systems-in-the-brain-and-the-eye-export-fluid-and-solutes-from_fig1_353240231
External Carotid Artery: Anatomy & Branches | Study.com
https://study.com/academy/lesson/external-carotid-artery-anatomy-branches.html
Cervical Node Mets fron Occult Primary
http://www.aboutcancer.com/cervical_node_occult_utd_907.htmep 46
Donate to the Front Line Covid-19 Critical Care Alliance, Inc. 
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Long Story Short Episode 46: Intermittent Fasting and Brain Health
Intermittent fasting causes production of beta hydroxybutarate, which in turn helps improve the glymphatic flow of fluids in the brain. This in turn leads to a better clearance of waste products from the brain, helping to improve the cognitive state, memory, and potentially stall the progress of dementia.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
URL list from Friday, Feb. 17 2023 19:11 PM
The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698404/
Frontiers | Perivascular Spaces, Glymphatic System and MR
https://www.frontiersin.org/articles/10.3389/fneur.2022.844938/full
Perivascular spaces and brain waste clearance systems: relevance for neurodegenerative and cerebrovascular pathology | SpringerLink
https://link.springer.com/article/10.1007/s00234-021-02718-7
Frontiers | Perivascular Unit: This Must Be the Place. The Anatomical Crossroad Between the Immune, Vascular and Nervous System
https://www.frontiersin.org/articles/10.3389/fnana.2020.00017/full
Neuroglia Lab : Glymphatics and virchow-robin space
http://visnu528.blogspot.com/2014/09/glymphatics-and-virchow-robin-space.html
Physiology and Clinical Relevance of Enlarged Perivascular Spaces in the Aging Brain | Neurology
https://n.neurology.org/content/98/3/107
Aquaporin-4 - Wikipedia
https://en.wikipedia.org/wiki/Aquaporin-4
Astrocyte - Wikipedia
https://en.wikipedia.org/wiki/Astrocyte
Neurocytology-Astrocytes
https://neuropathology-web.org/chapter1/chapter1bAstrocytes.html#:~:text=Astrocytic%20foot%20processes%20surround%20brain,maintains%20homeostasis%20in%20the%20CNS.
Blood-brain barrier | RIT
https://www.rit.edu/spotlights/blood-brain-barrier
The Blood-Brain Barrier | Morphology of Nervous System
https://sisu.ut.ee/histology/blood-brain-barrier
Elimination of substances from the brain parenchyma: efflux via perivascular pathways and via the blood–brain barrier | Fluids and Barriers of the CNS | Full Text
https://fluidsbarrierscns.biomedcentral.com/articles/10.1186/s12987-018-0113-6
The glymphatic systems in the brain and the eye export fluid and... | Download Scientific Diagram
https://www.researchgate.net/figure/The-glymphatic-systems-in-the-brain-and-the-eye-export-fluid-and-solutes-from_fig1_353240231
External Carotid Artery: Anatomy & Branches | Study.com
https://study.com/academy/lesson/external-carotid-artery-anatomy-branches.html
Cervical Node Mets fron Occult Primary
http://www.aboutcancer.com/cervical_node_occult_utd_907.htm
Donate to the Front Line Covid-19 Critical Care Alliance, Inc. 
To educate medical professionals and the public in safe and effective ways to prevent and treat COVID-19. Click here to make a donation:
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 45: Berberine and Pancreatic Beta Cells
Berberine has many important mechanisms. In the current series of talks we are presenting the mechanisms related to the management of Type 2 diabetes mellitus. In the current talk we look at the high level mechanism of how Berberine helps increase the insulin secretion.
Note: cell's depolarization process is intentionally skipped to keep the focus on the potassium channels.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
URL list from Sunday, Feb. 13, 2023
Berberine is an insulin secretagogue targeting the KCNH6 potassium channel | Nature Communications
https://www.nature.com/articles/s41467-021-25952-2
AMP-activated protein kinase - Wikipedia
https://en.wikipedia.org/wiki/AMP-activated_protein_kinase
Frontiers | Cerebral Gluconeogenesis and Diseases
https://www.frontiersin.org/articles/10.3389/fphar.2016.00521/full
Phosphoenolpyruvate carboxykinase - Wikipedia
https://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase
Gluconeogenesis - Wikipedia
https://en.wikipedia.org/wiki/Gluconeogenesis
Metformin - Wikipedia
https://en.wikipedia.org/wiki/Metformin
Sterol regulatory element-binding protein 1 - Wikipedia
https://en.wikipedia.org/wiki/Sterol_regulatory_element-binding_protein_1
The Role of Mammalian Target of Rapamycin (mTOR) in Insulin Signaling - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707648/
mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis | PNAS
https://www.pnas.org/doi/10.1073/pnas.1000323107
Insulin Signaling Pathway | Antibodies.com
https://www.antibodies.com/insulin-signaling-pathway
Regulation of SREBP by insulin signaling pathway | Download Scientific Diagram
https://www.researchgate.net/figure/Regulation-of-SREBP-by-insulin-signaling-pathway_fig3_258503248
The role of the KATP channel in glucose homeostasis in health and disease: more than meets the islet - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976015/
Donate to the Front Line Covid-19 Critical Care Alliance, Inc. 
To educate medical professionals and the public in safe and effective ways to prevent and treat COVID-19. Click here to make a donation:
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This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 43: Metabolic Syndrome Defined and How to Treat It (Dr. Been and Dr. Marik, from FLCCC Webinar February 8, 2023)
This is the second in a series of lectures on the incredible Chinese herbal medicine, berberine. This episode of 'Long Story Short' comes to us from last week's FLCCC Weekly Webinar with Dr. Mobeen Syed (Dr. Been) and Dr. Paul Marik.
The entire webinar can be viewed here: https://odysee.com/@FrontlineCovid19CriticalCareAlliance:c/Weekly_Webinar_Feb08:7?lid=898dc55e3da38738b1599323dbd3a835af8570b9
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
Donate to the Front Line Covid-19 Critical Care Alliance, Inc. 
To educate medical professionals and the public in safe and effective ways to prevent and treat COVID-19. Click here to make a donation:
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 43: How Berberine Helps Manage Type 2 Diabetes
This herbal Chinese medicine has an astonishingly amazing effect on insulin release, insulin receptor expressions, reduction in insulin resistance, reduction in gluconeogenesis, reduction in fatty acids, and improvement in liver cell health. Let's review it.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
URL list from Sunday, Feb. 5 2023
AMP-activated protein kinase - Wikipedia
https://en.wikipedia.org/wiki/AMP-activated_protein_kinase
Frontiers | Cerebral Gluconeogenesis and Diseases
https://www.frontiersin.org/articles/10.3389/fphar.2016.00521/full
Phosphoenolpyruvate carboxykinase - Wikipedia
https://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase
Gluconeogenesis - Wikipedia
https://en.wikipedia.org/wiki/Gluconeogenesis
Metformin - Wikipedia
https://en.wikipedia.org/wiki/Metformin
Sterol regulatory element-binding protein 1 - Wikipedia
https://en.wikipedia.org/wiki/Sterol_regulatory_element-binding_protein_1
The Role of Mammalian Target of Rapamycin (mTOR) in Insulin Signaling - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707648/
mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis | PNAS
https://www.pnas.org/doi/10.1073/pnas.1000323107
Insulin Signaling Pathway | Antibodies.com
https://www.antibodies.com/insulin-signaling-pathway
Regulation of SREBP by insulin signaling pathway | Download Scientific Diagram
https://www.researchgate.net/figure/Regulation-of-SREBP-by-insulin-signaling-pathway_fig3_258503248
The role of the KATP channel in glucose homeostasis in health and disease: more than meets the islet - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976015/
Donate to the Front Line Covid-19 Critical Care Alliance, Inc. 
To educate medical professionals and the public in safe and effective ways to prevent and treat COVID-19. Click here to make a donation:
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 42: Potential Role of Magnesium for Long COVID and Vaccine Injury
Magnesium is an essential mineral/nutrient required for more than 600 enzymatic actions in our body. Magnesium levels are also tied closely with the activation of vitamin D. Magnesium is involved in smooth muscle relaxation, neuroprotection, innate arm modulation, gut microbiome modulation, and much more. Let's look at the role of magnesium and importance of its adequate levels in our body.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
URL list from Friday, Jan. 27 2023
Home - FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
I-RECOVER-Post-Vaccine-Protocol.pdf
https://covid19criticalcare.com/wp-content/uploads/2022/12/I-RECOVER-Post-Vaccine-Protocol.pdf
Frontiers | Higher Intake of Dietary Magnesium Is Inversely Associated With COVID-19 Severity and Symptoms in Hospitalized Patients: A Cross-Sectional Study
https://www.frontiersin.org/articles/10.3389/fnut.2022.873162/full
The relevance of magnesium homeostasis in COVID-19 - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540865/
Frontiers | Can Maintaining Optimal Magnesium Balance Reduce the Disease Severity of COVID-19 Patients?
https://www.frontiersin.org/articles/10.3389/fendo.2022.843152/full
Impact of Magnesium Supplementation in Muscle Damage of Professional Cyclists Competing in a Stage Race - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723322/
The Role of Magnesium in Neurological Disorders - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024559/
Neural Mechanisms of Autonomic Dysfunction in Neurological Diseases
https://www.hindawi.com/journals/np/2017/2050191/
Magnesium relaxes arterial smooth muscle by decreasing intracellular Ca2+ without changing intracellular Mg2+. - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC295901/
Frontiers | The Role of Proprotein Convertases in the Regulation of the Function of Immune Cells in the Oncoimmune Response
https://www.frontiersin.org/articles/10.3389/fimmu.2021.667850/full
Elevation of brain magnesium prevents synaptic loss and reverses cognitive deficits in Alzheimer's disease mouse model - PubMed
https://pubmed.ncbi.nlm.nih.gov/25213836/
N-Methyl-D-aspartic acid - Wikipedia
https://en.wikipedia.org/wiki/N-Methyl-D-aspartic_acid
Timeline (Bioavailability) of Magnesium Compounds in Hours: Which Magnesium Compound Works Best? - PubMed
https://pubmed.ncbi.nlm.nih.gov/29679349/
[Significance of magnesium in cardiac arrhythmias] - PubMed
https://pubmed.ncbi.nlm.nih.gov/11105328/#:~:text=Magnesium%20is%20of%20great%20importance,AV%20node%20are%20both%20prolonged.
Donate to the Front Line Covid-19 Critical Care Alliance, Inc. 
To educate medical professionals and the public in safe and effective ways to prevent and treat COVID-19. Click here to make a donation:
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Celebrating 40 Episodes of Long Story Short!
Dr. Been shares a few words in celebration of 40 episodes of Long Story Short, including his hope for where we will be 40 episodes from now - that Long Story Short will be the definitive guide for individuals suffering from long COVID and vaccine injury, as well as for providers treating these patients.
Congratulations, Dr. Been, on an incredible first 40 lectures!
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
Donate to the Front Line Covid-19 Critical Care Alliance, Inc. 
To educate medical professionals and the public in safe and effective ways to prevent and treat COVID-19. Click here to make a donation:
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 41: Melatonin and Near Infrared Light (NIR)
Being in the morning and evening sunlight and being in the green places should be an important part of life. Let's see why.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
References (January 13, 2023):
Melatonin and the Optics of the Human Body | Melatonin Research
https://www.melatonin-research.net/index.php/MR/article/view/19
NF-κB Drives the Synthesis of Melatonin in RAW 264.7 Macrophages by Inducing the Transcription of the Arylalkylamine-N-Acetyltransferase (AA-NAT) Gene | PLOS ONE
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052010
Aralkylamine N-acetyltransferase - Wikipedia
https://en.wikipedia.org/wiki/Aralkylamine_N-acetyltransferase
Melatonin: A mitochondrial resident with a diverse skill set - ScienceDirect
https://www.sciencedirect.com/science/article/abs/pii/S0024320522003125
Donate to the Front Line Covid-19 Critical Care Alliance, Inc. 
To educate medical professionals and the public in safe and effective ways to prevent and treat COVID-19. Click here to make a donation:
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 40: Long COVID Symptom Clusters - Fatigue, Cognitive and Respiratory
Today’s discussion looks at the latest study on long COVID symptom clusters and their proportions. The findings are fascinating. Watch now.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
URL list from Friday, Jan. 6 2023
Long COVID stemmed from mild cases of COVID-19 in most people, according to a new multicountry study
https://www.yahoo.com/news/long-covid-stemmed-mild-cases-132806892.html
Estimated Global Proportions of Individuals With Persistent Fatigue, Cognitive, and Respiratory Symptom Clusters Following Symptomatic COVID-19 in 2020 and 2021 | Neurology | JAMA | JAMA Network
https://jamanetwork.com/journals/jama/fullarticle/2797443
I-RECOVER: Post-Vaccine Treatment - FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/treatment-protocols/i-recover/
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 39: Is Nattokinase Protective Against SARS-COV-2?
Nattokinase is thrombolytic, spike protein degradative, and anti-aging enzyme produced by Bacillus subtilis. Is it protective against SARS-COV-2? Let’s take a look.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
URL list from Monday, Dec. 19 2022
File:Natto mixed by Kinchan1.jpg - Wikimedia Commons
https://commons.wikimedia.org/wiki/File:Natto_mixed_by_Kinchan1.jpg
Nattokinase: An Oral Antithrombotic Agent for the Prevention of Cardiovascular Disease - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372539/#:~:text=Mechanism%20of%20Action.,activator%20(t%2DPA)
Degradative Effect of Nattokinase on Spike Protein of SARS-CoV-2 - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458005/
A single-dose of oral nattokinase potentiates thrombolysis and anti-coagulation profiles | Scientific Reports
https://www.nature.com/articles/srep11601
Mechanism of Action. Nattokinase dissolves blood clots by directly... | Download Scientific Diagram
https://www.researchgate.net/figure/Fig-2-Mechanism-of-Action-Nattokinase-dissolves-blood-clots-by-directly-hydrolyzing_fig2_321687198
Coagulation and fibrinolytic cascades. Ca, calcium; FDPs, fibrin... | Download Scientific Diagram
https://www.researchgate.net/figure/Coagulation-and-fibrinolytic-cascades-Ca-calcium-FDPs-fibrin-degradation-product_fig2_284136686
Coagulation and anticoagulation in idiopathic pulmonary fibrosis | European Respiratory Society
https://err.ersjournals.com/content/24/137/392.figures-only
Coagulation Clotting Mechanisms - Circulatory System - MCAT Content
https://jackwestin.com/resources/mcat-content/circulatory-system/coagulation-clotting-mechanisms
Physiology, Coagulation Pathways - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK482253/#:~:text=The%20intrinsic%20pathway%20is%20activated,endothelial%20cells%20after%20external%20damage.&text=This%20pathway%20is%20the%20longer%20pathway%20of%20secondary%20hemostasis.
Intrinsic Pathway of Coagulation and Thrombosis | Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.ahajournals.org/doi/full/10.1161/ATVBAHA.118.312130
Plasmin - Wikipedia
https://en.wikipedia.org/wiki/Plasmin
Urokinase - Wikipedia
https://en.wikipedia.org/wiki/Urokinase
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 38: Nattokinase Antithrombotic Mechanism of Action
Nattokinase Part 1 of 3 (to be followed by Part 2: Nattokinase and The Degradation of the Spike Protein and Part 3: Nattokinase: Dosing and Safety)
Nattokinase is a thrombolytic, spike protein degradative, and anti-aging enzyme produced by Bacillus subtilis. Nattokinase is made by fermenting soybeans with Bacillus subtilis. Let's review its actions.
URL list from Monday, Dec. 19 2022
File:Natto mixed by Kinchan1.jpg - Wikimedia Commons
https://commons.wikimedia.org/wiki/File:Natto_mixed_by_Kinchan1.jpg
Nattokinase: An Oral Antithrombotic Agent for the Prevention of Cardiovascular Disease - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372539/#:~:text=Mechanism%20of%20Action.,activator%20(t%2DPA)
Degradative Effect of Nattokinase on Spike Protein of SARS-CoV-2 - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458005/
A single-dose of oral nattokinase potentiates thrombolysis and anti-coagulation profiles | Scientific Reports
https://www.nature.com/articles/srep11601
Mechanism of Action. Nattokinase dissolves blood clots by directly... | Download Scientific Diagram
https://www.researchgate.net/figure/Fig-2-Mechanism-of-Action-Nattokinase-dissolves-blood-clots-by-directly-hydrolyzing_fig2_321687198
Coagulation and fibrinolytic cascades. Ca, calcium; FDPs, fibrin... | Download Scientific Diagram
https://www.researchgate.net/figure/Coagulation-and-fibrinolytic-cascades-Ca-calcium-FDPs-fibrin-degradation-product_fig2_284136686
Coagulation and anticoagulation in idiopathic pulmonary fibrosis | European Respiratory Society
https://err.ersjournals.com/content/24/137/392.figures-only
Coagulation Clotting Mechanisms - Circulatory System - MCAT Content
https://jackwestin.com/resources/mcat-content/circulatory-system/coagulation-clotting-mechanisms
Physiology, Coagulation Pathways - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK482253/#:~:text=The%20intrinsic%20pathway%20is%20activated,endothelial%20cells%20after%20external%20damage.&text=This%20pathway%20is%20the%20longer%20pathway%20of%20secondary%20hemostasis.
Intrinsic Pathway of Coagulation and Thrombosis | Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.ahajournals.org/doi/full/10.1161/ATVBAHA.118.312130
Plasmin - Wikipedia
https://en.wikipedia.org/wiki/Plasmin
Urokinase - Wikipedia
https://en.wikipedia.org/wiki/Urokinase
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 37: Photobiomodulation (PBM) is Neuroprotective
Photobiomodulation and methylene blue are neuroprotective. These interventions not only reduce cellular apoptosis, but also improve the tissue healing by improving the blood flow to the tissues. Let's review how photobiomodulation works to help mitochondria heal and function correctly.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
Reference:
Mitochondria as a target for neuroprotection: role of methylene blue and photobiomodulation | Translational Neurodegeneration | Full Text
https://translationalneurodegeneration.biomedcentral.com/articles/10.1186/s40035-020-00197-z
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 36: Intermittent Fasting for Women
Dr. Paul Marik joins Dr. Been for a discussion on intermittent fasting (IF), especially for reproductive aged women.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
URL list from Friday, Nov. 25 2022
Glucose tolerance and skeletal muscle gene expression in response to alternate day fasting - PubMed
https://pubmed.ncbi.nlm.nih.gov/15833943/
Sex-dependent metabolic, neuroendocrine, and cognitive responses to dietary energy restriction and excess - PubMed
https://pubmed.ncbi.nlm.nih.gov/17569758/
Intermittent Fasting Dietary Restriction Regimen Negatively Influences Reproduction in Young Rats: A Study of Hypothalamo-Hypophysial-Gonadal Axis - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558496/
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 35: Oral Dosage For Methylene Blue - FLCCC Protocol Review
In this talk we will go over the FLCCC's recommendation for the oral methylene blue dosage. Full I-RECOVER Protocol can be found here: https://covid19criticalcare.com/treatment-protocols/i-recover/
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
References December 1, 2022:
Read side-effects, precautions, and contraindications here:
https://www.drugs.com/dosage/methylene-blue.html
https://www.rxlist.com/methylene-blue-side-effects-drug-center.htm#overview
Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue - PubMed
https://pubmed.ncbi.nlm.nih.gov/22067440/
Frontiers | Protection against neurodegeneration with low-dose methylene blue and near-infrared light
https://www.frontiersin.org/articles/10.3389/fncel.2015.00179/full
Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265679/
A two-year double-blind crossover trial of the prophylactic effect of methylene blue in manic-depressive psychosis - PubMed
https://pubmed.ncbi.nlm.nih.gov/3091097/
Methylene Blue: Generic, Uses, Side Effects, Dosages, Interactions, Warnings
https://www.rxlist.com/consumer_provayblue_methylene_blue/drugs-condition.htm
Methylene-Blue-Cognitive-Vitality-For-Researchers.pdf
https://www.alzdiscovery.org/uploads/cognitive_vitality_media/Methylene-Blue-Cognitive-Vitality-For-Researchers.pdf
Methylene blue Side Effects: Common, Severe, Long Term - Drugs.com
https://www.drugs.com/sfx/methylene-blue-side-effects.html
METHYLENE BLUE - ORAL (Urolene Blue) side effects, medical uses, and drug interactions.
https://www.medicinenet.com/methylene_blue-oral/article.htm
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 34: Methylene Blue (MB) Dosage and Administration Approaches
Numerous studies have shown the neuroprotective effect of methylene blue (MB). It seems that MB can be used for brain fog, confusion, memory issues, and mitochondrial dysfunction in neurons. In this talk we will look at the practical aspect of methylene blue administration.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
URL list from Friday, Nov. 18 2022
Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue - PubMed
https://pubmed.ncbi.nlm.nih.gov/22067440/
Frontiers | Protection against neurodegeneration with low-dose methylene blue and near-infrared light
https://www.frontiersin.org/articles/10.3389/fncel.2015.00179/full
Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265679/
A two-year double-blind crossover trial of the prophylactic effect of methylene blue in manic-depressive psychosis - PubMed
https://pubmed.ncbi.nlm.nih.gov/3091097/
Methylene Blue: Generic, Uses, Side Effects, Dosages, Interactions, Warnings
https://www.rxlist.com/consumer_provayblue_methylene_blue/drugs-condition.htm
Methylene-Blue-Cognitive-Vitality-For-Researchers.pdf
https://www.alzdiscovery.org/uploads/cognitive_vitality_media/Methylene-Blue-Cognitive-Vitality-For-Researchers.pdf
Methylene blue Side Effects: Common, Severe, Long Term - Drugs.com
https://www.drugs.com/sfx/methylene-blue-side-effects.html
METHYLENE BLUE - ORAL (Urolene Blue) side effects, medical uses, and drug interactions.
https://www.medicinenet.com/methylene_blue-oral/article.htm
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 33: Methylene Blue and Near Infrared Light for Neuroprotection
Studies show that neurons are metabolically protected when low dose Methylene Blue is administered systemically. Methylene Blue promotes energy metabolism and neuronal survival. A similar protective effect is observed with near infrared light. Let's review.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
References
URL list from Thursday, Nov. 10 2022
Frontiers | Protection against neurodegeneration with low-dose methylene blue and near-infrared light
https://www.frontiersin.org/articles/10.3389/fncel.2015.00179/full
Methylene Blue Reduces Acute Cerebral Ischemic Injury via the Induction of Mitophagy | Molecular Medicine | Full Text
https://molmed.biomedcentral.com/articles/10.2119/molmed.2015.00038
Effect of Methylene Blue on White Matter Injury after Ischemic Stroke - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872771/
Repurposing methylene blue in the management of COVID-19: Mechanistic aspects and clinical investigations - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352658/
Frontiers | Methylene Blue Reduces Neuronal Apoptosis and Improves Blood-Brain Barrier Integrity After Traumatic Brain Injury
https://www.frontiersin.org/articles/10.3389/fneur.2019.01133/full
Addressing Personal Protective Equipment (PPE) Decontamination: Methylene Blue and Light Inactivates SARS-CoV-2 on N95 Respirators and Masks with Maintenance of Integrity and Fit | medRxiv
https://www.medrxiv.org/content/10.1101/2020.12.11.20236919v2.full
Mitochondria as a target for neuroprotection: role of methylene blue and photobiomodulation
https://translationalneurodegeneration.biomedcentral.com/articles/10.1186/s40035-020-00197-z
Photobiomodulation as a treatment for neurodegenerative disorders: current and future trends - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694374/
Shining light on the head: Photobiomodulation for brain disorders - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066074/
Nitric Oxide, Cytochrome C Oxidase, and the Cellular Response to Hypoxia | Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.ahajournals.org/doi/10.1161/ATVBAHA.108.181628
Mitochondrial electron transport chain, ROS generation and uncoupling (Review)
https://www.spandidos-publications.com/10.3892/ijmm.2019.4188#:~:text=The%20sites%20of%20ROS%20production,peroxide%20(48%2C49).
Frontiers | Mitochondrial Reactive Oxygen Species and Their Contribution in Chronic Kidney Disease Progression Through Oxidative Stress
https://www.frontiersin.org/articles/10.3389/fphys.2021.627837/full#:~:text=Mitochondrial%20reactive%20oxygen%20species%20are,et%20al.%2C%202013).
Mitochondria—Fundamental to Life and Health - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684129/
After Treatment with Methylene Blue is Effective against Delayed Encephalopathy after Acute Carbon Monoxide Poisoning - PubMed
https://pubmed.ncbi.nlm.nih.gov/29151273/
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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Long Story Short Episode 32: Types of Protein Recycling and Inflammatory Diseases
Types of Protein Recycling and Inflammatory Diseases
In this era of inflammatory state that we all will suffer either from the SARS-COV-2 or vaccines in some, it becomes critically important to understand the mechanisms that are disrupted resulting in the chronic inflammation. This understanding enables a provider to think about the management. This talk will empower you to manage your patients with chronic inflammatory conditions more successfully.
DrBeen: Medical Education Online
https://www.drbeen.com/
FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/
URL list from Friday, Sep. 23 2022
How to Activate Heat Shock Proteins in a Sauna - Sauna Marketplace
https://saunamarketplace.com/how-to-activate-heat-shock-proteins-sauna/
Heat shock proteins and heat therapy for type 2 diabetes: pros and cons - PubMed
https://pubmed.ncbi.nlm.nih.gov/26049635/
Heat shock proteins and heat therapy for type 2 diabetes: pr... : Current Opinion in Clinical Nutrition & Metabolic Care
https://journals.lww.com/co-clinicalnutrition/Abstract/2015/07000/Heat_shock_proteins_and_heat_therapy_for_type_2.10.aspx
Heat shock proteins and immune system - PubMed
https://pubmed.ncbi.nlm.nih.gov/19276179/
Clinical Effects of Regular Dry Sauna Bathing: A Systematic Review - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941775/
Heat shock proteins regulate activation-induced proteasomal degradation of the mature phosphorylated form of protein kinase C - PubMed
https://pubmed.ncbi.nlm.nih.gov/23900841/
Heat Shock Proteins - ScienceDirect
https://www.sciencedirect.com/science/article/pii/B9780123749840006859
Molecular chaperones in protein folding and proteostasis | Nature
https://www.nature.com/articles/nature10317
Pathways of chaperone-mediated protein folding in the cytosol | Nature Reviews Molecular Cell Biology
https://www.nature.com/articles/nrm1492#access-options
Chaperonin - Wikipedia
https://en.wikipedia.org/wiki/Chaperonin
Frontiers | Heat-Shock Proteins in Neuroinflammation
https://www.frontiersin.org/articles/10.3389/fphar.2019.00920/full
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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