Long Story Short with Dr. Been

Antinuclear Antibodies - A Primer for Providers DrBeen: Medical Education Online https://www.drbeen.com/ FLCCC | Front Line COVID-19 Critical Care Alliance https://covid19criticalcare.com/ URL list from Thursday, Oct. 29 2022 Circulating anti-nuclear autoantibodies in COVID-19 survivors predict long-COVID symptoms | European Respiratory Society https://erj.ersjournals.com/content/early/2022/08/04/13993003.00970-2022 Anti-SSB/La is one of the antineutrophil autoantibodies responsible for neutropenia and functional impairment of polymorphonuclear neutrophils in patients with systemic lupus erythematosus - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808654/ U1 spliceosomal RNA - Wikipedia https://en.wikipedia.org/wiki/U1_spliceosomal_RNA Antinuclear antibodies: cause of disease or caused by disease? | Rheumatology | Oxford Academic https://academic.oup.com/rheumatology/article/39/6/581/1783869 Histones - an overview | ScienceDirect Topics https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/histones Antinuclear Antibodies (ANA) https://www.rheumatology.org/I-Am-A/Patient-Caregiver/Diseases-Conditions/Antinuclear-Antibodies-ANA Linker DNA - Wikipedia https://en.wikipedia.org/wiki/Linker_DNA Biochemistry, Antinuclear Antibodies (ANA) - StatPearls - NCBI Bookshelf https://www.ncbi.nlm.nih.gov/books/NBK537071/ Rheumatic Diseases - Mayo Clinic Health System https://www.mayoclinichealthsystem.org/locations/mankato/services-and-treatments/rheumatology/rheumatic-diseases Antinuclear antibody - Wikipedia https://en.wikipedia.org/wiki/Antinuclear_antibody Patient education: Antinuclear antibodies (ANA) (Beyond the Basics) - UpToDate https://www.uptodate.com/contents/antinuclear-antibodies-ana-beyond-the-basics/print Nuclear localizing anti-DNA antibodies enter cells via caveoli and modulate expression of caveolin and p53 - PubMed https://pubmed.ncbi.nlm.nih.gov/15829407/ In vivo cell penetration and intracellular transport of anti-Sm and anti-La autoantibodies | International Immunology | Oxford Academic https://academic.oup.com/intimm/article/12/4/415/693650 Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. CSID: 1f365820feb79ca7 Content Managed by ContentSafe.co

Antinuclear Antibodies as Predictors of Long COVID In this discussion we will go over a Canadian study about the persistence of the ANA and inflammatory mediators that predict long COVID symptoms. There's good news as well that these mediators and antibodies reduce over time. URL list from Thursday, Oct. 29 2022 Circulating anti-nuclear autoantibodies in COVID-19 survivors predict long-COVID symptoms | European Respiratory Society https://erj.ersjournals.com/content/early/2022/08/04/13993003.00970-2022 Anti-SSB/La is one of the antineutrophil autoantibodies responsible for neutropenia and functional impairment of polymorphonuclear neutrophils in patients with systemic lupus erythematosus - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808654/ U1 spliceosomal RNA - Wikipedia https://en.wikipedia.org/wiki/U1_spliceosomal_RNA Antinuclear antibodies: cause of disease or caused by disease? | Rheumatology | Oxford Academic https://academic.oup.com/rheumatology/article/39/6/581/1783869 Histones - an overview | ScienceDirect Topics https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/histones Antinuclear Antibodies (ANA) https://www.rheumatology.org/I-Am-A/Patient-Caregiver/Diseases-Conditions/Antinuclear-Antibodies-ANA Linker DNA - Wikipedia https://en.wikipedia.org/wiki/Linker_DNA Biochemistry, Antinuclear Antibodies (ANA) - StatPearls - NCBI Bookshelf https://www.ncbi.nlm.nih.gov/books/NBK537071/ Rheumatic Diseases - Mayo Clinic Health System https://www.mayoclinichealthsystem.org/locations/mankato/services-and-treatments/rheumatology/rheumatic-diseases Antinuclear antibody - Wikipedia https://en.wikipedia.org/wiki/Antinuclear_antibody Patient education: Antinuclear antibodies (ANA) (Beyond the Basics) - UpToDate https://www.uptodate.com/contents/antinuclear-antibodies-ana-beyond-the-basics/print Nuclear localizing anti-DNA antibodies enter cells via caveoli and modulate expression of caveolin and p53 - PubMed https://pubmed.ncbi.nlm.nih.gov/15829407/ In vivo cell penetration and intracellular transport of anti-Sm and anti-La autoantibodies | International Immunology | Oxford Academic https://academic.oup.com/intimm/article/12/4/415/693650 Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. CSID: 799cb195476a292e Content Managed by ContentSafe.co

Ep 29: Spikopathy - How Spike Protein Causes Pathologies in Our Tissues and Vessels In this discussion we will go over the important pathologic mechanisms behind the diseases caused by the spike protein. DrBeen: Medical Education Online https://www.drbeen.com/ FLCCC | Front Line COVID-19 Critical Care Alliance https://covid19criticalcare.com/ URL list from Friday, Oct. 21 2022 Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies | Acta Pharmacologica Sinica https://www.nature.com/articles/s41401-022-00998-0 Frontiers | SARS-CoV-2 Spike Protein Induces Degradation of Junctional Proteins That Maintain Endothelial Barrier Integrity https://www.frontiersin.org/articles/10.3389/fcvm.2021.687783/full SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2 | Circulation Research https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.121.318902 Mitochondrial Dynamics in SARS-COV2 Spike Protein Treated Human Microglia: Implications for Neuro-COVID - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487226/ The spike protein of SARS-CoV-2 induces endothelial inflammation through integrin α5β1 and NF-κB signaling - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820157/ IJMS | Free Full-Text | New Therapeutic Implications of Endothelial Nitric Oxide Synthase (eNOS) Function/Dysfunction in Cardiovascular Disease | HTML https://www.mdpi.com/1422-0067/20/1/187/htm Molecular mimicry and autoimmunity - PubMed https://pubmed.ncbi.nlm.nih.gov/30509385/ Endothelial NOS - Wikipedia https://en.wikipedia.org/wiki/Endothelial_NOS ACE/ACE2 balance might be instrumental to explain the certain comorbidities leading to severe COVID-19 cases - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856554/ Oxidative stress-induced endothelial dysfunction and decreased vascular nitric oxide in COVID-19 patients - eBioMedicine https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(22)00077-9/fulltext l-Arginine and COVID-19: An Update - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619186/ l-Arginine supplementation enhances eNOS expression in experimental model of hypercholesterolemic rabbits aorta - PubMed https://pubmed.ncbi.nlm.nih.gov/19168337/ Implications of SARS-Cov-2 infection on eNOS and iNOS activity: Consequences for the respiratory and vascular systems - ScienceDirect https://www.sciencedirect.com/science/article/pii/S1089860321000380 Induction of citrulline-nitric oxide (NO) cycle enzymes and NO production in immunostimulated rat RPE-J cells - PubMed https://pubmed.ncbi.nlm.nih.gov/12589771/ Oct 21, 2022 at 4:58 PM Oxidative Stress, Nitric Oxide Synthase, and Superoxide Dismutase https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.107.103226 Oct 21, 2022 at 5:09 PM Critical Role of the Nitric Oxide/Reactive Oxygen Species Balance in Endothelial Progenitor Dysfunction https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135185/ Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. CSID: 172b29ff3a55ac06 Content Managed by ContentSafe.co

Ep 28: Spike Proteins Disrupt Nitric Oxide Let's review how the spike protein alone can cause dysregulation of the ACE2 bearning cells. One important mechanism is the reduction in the expression of the endothelial nitric oxide synthase (eNOS) enzyme. Let's review. DrBeen: Medical Education Online https://www.drbeen.com/ FLCCC | Front Line COVID-19 Critical Care Alliance https://covid19criticalcare.com/ URL list from Sunday, Oct. 9 2022 SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2 | Circulation Research https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.121.318902 Mitochondrial Dynamics in SARS-COV2 Spike Protein Treated Human Microglia: Implications for Neuro-COVID - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487226/ Endothelial NOS - Wikipedia https://en.wikipedia.org/wiki/Endothelial_NOS The novel coronavirus’ spike protein plays additional key role in illness - Salk Institute for Biological Studies https://www.salk.edu/news-release/the-novel-coronavirus-spike-protein-plays-additional-key-role-in-illness/ ACE/ACE2 balance might be instrumental to explain the certain comorbidities leading to severe COVID-19 cases - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856554/ The spike protein of SARS-CoV-2 induces endothelial inflammation through integrin α5β1 and NF-κB signaling - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820157/ Oxidative stress-induced endothelial dysfunction and decreased vascular nitric oxide in COVID-19 patients - eBioMedicine https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(22)00077-9/fulltext l-Arginine and COVID-19: An Update - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619186/ l-Arginine supplementation enhances eNOS expression in experimental model of hypercholesterolemic rabbits aorta - PubMed https://pubmed.ncbi.nlm.nih.gov/19168337/ Implications of SARS-Cov-2 infection on eNOS and iNOS activity: Consequences for the respiratory and vascular systems - ScienceDirect https://www.sciencedirect.com/science/article/pii/S1089860321000380 Induction of citrulline-nitric oxide (NO) cycle enzymes and NO production in immunostimulated rat RPE-J cells - PubMed https://pubmed.ncbi.nlm.nih.gov/12589771/ Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. CSID: f863a91b0797c53b Content Managed by ContentSafe.co

Ep 26: Near Infrared Light Therapy Reduces Inflammation Near infrared light therapy reduces inflammatory mediators by 50% and IL6 by 80%. Let's review. DrBeen: Medical Education Online https://www.drbeen.com/ FLCCC | Front Line COVID-19 Critical Care Alliance https://covid19criticalcare.com/ URL list from Thursday, Sep. 15 2022 Infrared light therapy relieves TLR-4 dependent hyper-inflammation of the type induced by COVID-19 - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451450/ Not scientific but interesting article about heat-shock proteins and infrared. Infrared Sauna Use And Heat Shock Proteins https://saunas.org/infrared-sauna-use-and-heat-shock-proteins/ Some more references Near-infrared spectroscopy - Wikipedia https://en.wikipedia.org/wiki/Near-infrared_spectroscopy Near Infrared (NIR) Light Therapy of Eye Diseases: A Review - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738953/#:~:text=NIR%20and%20LEDs%20light%20can,modify%20biological%20functions%20of%20cells. Sep 15, 2022 at 10:13 PM Red Light Therapy vs. Infrared Sauna https://youtu.be/vwgLlYcYZ_4 Red/near-infrared irradiation therapy for treatment of central nervous system injuries and disorders - PubMed https://pubmed.ncbi.nlm.nih.gov/23492552/ The Benefits of Near-Infrared Light Therapy https://platinumtherapylights.com/blogs/news/near-infrared-light-therapy Near-Infrared Light and Skin: Why Intensity Matters - Abstract - Challenges in Sun Protection - Karger Publishers https://www.karger.com/Article/Abstract/517645 The effect of red-to-near-infrared (R/NIR) irradiation on inflammatory processes - PubMed https://pubmed.ncbi.nlm.nih.gov/31170016/#:~:text=Introduction%3A%20Near%2Dinfrared%20(NIR,blood%20flow%20and%20tissue%20oxygenation. Near-infrared light reduces glia activation and modulates neuroinflammation in the brains of diet-induced obese mice | Scientific Reports https://www.nature.com/articles/s41598-022-14812-8 Near-infrared light reduces β-amyloid-stimulated microglial toxicity and enhances survival of neurons: mechanisms of light therapy for Alzheimer’s disease | Alzheimer's Research & Therapy | Full Text https://alzres.biomedcentral.com/articles/10.1186/s13195-022-01022-7 Infrared light therapy relieves TLR-4 dependent hyper-inflammation of the type induced by COVID-19 - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451450/ What Is Near-Infrared Light? - StoneLock https://stonelock.com/what-is-near-infrared-light/#:~:text=Infrared%20Light%20(IR)%20is%20the,past%20what%20we%20can%20see. Toll-like receptor 4 - Wikipedia https://en.wikipedia.org/wiki/Toll-like_receptor_4 NF-κB - Wikipedia https://en.wikipedia.org/wiki/NF-%CE%BAB Lipopolysaccharide https://en.wikipedia.org/wiki/Lipopolysaccharide Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. CSID: 2f4cdaed97ce3583 Content Managed by ContentSafe.co

Ep 25: When The RNA Won't Go Away This ground breaking case reports demonstrate for the first time the evidence for the SARS-COV-2 persistence. Let's review. DrBeen: Medical Education Online https://www.drbeen.com/ FLCCC | Front Line COVID-19 Critical Care Alliance https://covid19criticalcare.com/ URL list from Tuesday, Sep. 6 2022 Frontiers | Case report: Persistence of residual antigen and RNA of the SARS-CoV-2 virus in tissues of two patients with long COVID https://www.frontiersin.org/articles/10.3389/fimmu.2022.939989/full fimmu-13-939989-t001.jpg (1460×1213) https://www.frontiersin.org/files/Articles/939989/fimmu-13-939989-HTML/image_m/fimmu-13-939989-t001.jpg fimmu-13-939989-g001.jpg (1565×1109) https://www.frontiersin.org/files/Articles/939989/fimmu-13-939989-HTML/image_m/fimmu-13-939989-g001.jpg fimmu-13-939989-g002.jpg (1562×752) https://www.frontiersin.org/files/Articles/939989/fimmu-13-939989-HTML/image_m/fimmu-13-939989-g002.jpg CD68 - Wikipedia https://en.wikipedia.org/wiki/CD68 CD14 - Wikipedia https://en.wikipedia.org/wiki/CD14 Functions of CD169 positive macrophages in human diseases (Review) https://www.spandidos-publications.com/10.3892/br.2020.1402#:~:text=CD169%2B%20macrophages%20are%20reported%20to%20be%20the%20primary%20cell%20type,30%2C76%2C77). Exploitation of the Macrophage Mannose Receptor (CD206) in Infectious Disease Diagnostics and Therapeutics - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963702/#:~:text=The%20macrophage%20mannose%20receptor%20(MR,homeostasis%20by%20scavenging%20unwanted%20mannoglycoproteins. Long COVID risk falls only slightly after vaccination, huge study shows https://www.nature.com/articles/d41586-022-01453-0 Association Between BNT162b2 Vaccination and Long COVID After Infections Not Requiring Hospitalization in Health Care Workers | Vaccination | JAMA | JAMA Network https://jamanetwork.com/journals/jama/fullarticle/2794072 Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study - The Lancet Respiratory Medicine https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(22)00127-8/fulltext Women more likely to have long COVID, different symptom profile https://www.cidrap.umn.edu/news-perspective/2022/06/women-more-likely-have-long-covid-different-symptom-profile#:~:text=For%20long%20COVID%2C%20females%20were,interval%2C%200.75%20to%200.93). Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. Content Managed by ContentSafe.co

Episode 21: Cardiovascular Effects of mRNA COVID-19 Vaccines in Adolescents (Preprint Thai Study) In this prospective cohort study of school children receiving BNT162b2 mRNA COVID-19 vaccines, researchers from Thailand have stunning data. Let's review. DrBeen: Medical Education Online https://www.drbeen.com/ FLCCC | Front Line COVID-19 Critical Care Alliance https://covid19criticalcare.com/ URL list from Monday, Aug. 15 2022 Cardiovascular Effects of the BNT162b2 mRNA COVID-19 Vaccine in Adolescents[v1] | Preprints https://www.preprints.org/manuscript/202208.0151/v1 Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to August 2021 | Vaccination | JAMA | JAMA Network https://jamanetwork.com/journals/jama/fullarticle/2788346 Related document to the above letter https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2021-06/05-COVID-Wallace-508.pdf Myocarditis after BNT162b2 Vaccination in Israeli Adolescents | NEJM https://www.nejm.org/doi/full/10.1056/NEJMc2116999 Persistent Cardiac Magnetic Resonance Imaging Findings in a Cohort of Adolescents with Post-Coronavirus Disease 2019 mRNA Vaccine Myopericarditis - The Journal of Pediatrics https://www.jpeds.com/article/S0022-3476(22)00282-7/fulltext#%20 CPK-MB test - Wikipedia https://en.wikipedia.org/wiki/CPK-MB_test Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. Content Managed by ContentSafe.co

The inspiration for Dr. Been’s ‘Long (Covid) Story Short’ came from the current need to explore chronic inflammation, as inflammatory illnesses already plagued over half of Americans and much of the global population. Furthermore, with COVID-19 and vaccines, there will be vast numbers of long COVID and vaccine injuries for years to come. We have to understand inflammation, now more than ever before, and learn to approach chronic inflammation and diseases with lifestyle changes that can help us cope and heal. DrBeen: Medical Education Online https://www.drbeen.com/ FLCCC | Front Line COVID-19 Critical Care Alliance https://covid19criticalcare.com/ Content Managed by ContentSafe.co

Long Story Short with Dr. Been Episode 17: Autophagy with Intermittent Fasting, Spermidine and Resveratrol In this lecture we explore autophagy - what it is and how it works to clear pathogens (virus, bacteria, fungus, other offending agents) from the cell. The presence of spike protein within a cell can make autophagy impossible as SARS-COV-2 and spike protein inhibits the process. To overcome this, intermittent fasting, resveratrol, spermidine and some other therapeutics that can be used forpotentiallygreat effect. DrBeen: Medical Education Online https://www.drbeen.com/ FLCCC | Front Line COVID-19 Critical Care Alliance https://covid19criticalcare.com/ URL List: Spermidine:https://www.biorxiv.org/content/10.1101/2020.04.15.997254v1 Resveratrol:https://www.mdpi.com/1420-3049/27/8/2376 https://www.frontiersin.org/articles/10.3389/fimmu.2021.670955/full https://www.frontiersin.org/articles/10.3389/fchem.2020.589769/full Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. Content Managed by ContentSafe.co

Long Story Short with Dr. Been Episode 15: Reinfection and Risk of Long COVID and Severe Outcomes - COVID Reinfection Outcomes Are Not Good (Preprint Study) This study shows that a reinfection increases the risk of hospitalization, death and sequela regardless of the vaccination status. Let's review. DrBeen: Medical Education Online https://www.drbeen.com/ FLCCC | Front Line COVID-19 Critical Care Alliance https://covid19criticalcare.com/ URL list from Saturday, Jul. 9 2022 Outcomes of SARS-CoV-2 Reinfection | Research Square https://www.researchsquare.com/article/rs-1749502/v1 Duration of immune protection of SARS-CoV-2 natural infection against reinfection in Qatar | medRxiv https://www.medrxiv.org/content/10.1101/2022.07.06.22277306v1 Outcomes of SARS-CoV-2 Reinfection | Research Square https://www.researchsquare.com/article/rs-1749502/v1 Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. Content Managed by ContentSafe.co

Long Story Short with Dr. Been Episode 13: Dandelion Leaf Extract Reduces Spike Binding | In-Vitro Study In this in-vitro study researchers from the University of Munich show that dandelion leaf extract has a potent inhibitory effect on the SARS-COV-2 spike binding to ACE2. Let's review. DrBeen: Medical Education Online https://www.drbeen.com/ Home - FLCCC | Front Line COVID-19 Critical Care Alliance https://covid19criticalcare.com/ URL list from Monday, June 13, 2022 In Vitro Effect of Taraxacum officinale Leaf Aqueous Extract on the Interaction between ACE2 Cell Surface Receptor and SARS-CoV-2 Spike Protein D614 and Four Mutants - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538008/ Dandelion | NCCIH https://www.nccih.nih.gov/health/dandelion Taraxacum - Wikipedia https://en.wikipedia.org/wiki/Taraxacum Dandelion Information | Mount Sinai - New York https://www.mountsinai.org/health-library/herb/dandelion Taraxacum officinale - Wikipedia https://en.wikipedia.org/wiki/Taraxacum_officinale DANDELION: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews https://www.webmd.com/vitamins/ai/ingredientmono-706/dandelion Lentivirus - Wikipedia https://en.wikipedia.org/wiki/Lentivirus Retrovirus - Wikipedia https://en.wikipedia.org/wiki/Retrovirus Home - ESCOP https://escop.com/ COVID-19 medical misinformation policy - YouTube Help https://support.google.com/youtube/answer/9891785?hl=en In Vitro Effect of Taraxacum officinale Leaf Aqueous Extract on the Interaction between ACE2 Cell Surface Receptor and SARS-CoV-2 Spike Protein D614 and Four Mutants - PubMed https://pubmed.ncbi.nlm.nih.gov/34681279/ Buy FLCCC gear: https://supportflccc.store/ Subscribe to our mailing list on our website: http://flccc.net/signup Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. Content Managed by ContentSafe.co

Long Story Short with Dr. Been Episode 11: Chronic Inflammation (Part 3) - Immune Regulation Mechanisms Continuing with the chronic inflammation series, we will now do a deeper dive in order to understand the regulatory mechanisms of the immune system. In this episode of Long Story Short, we will demonstrate a few examples including persistence of the antigen, negative feedback mechanisms for the innate arm, roles of IL-10, IFN-gamma, and IL-12, antibody feedback and more. In the next episode we will discuss the role of T Regulatory (TReg) cells. DrBeen: Medical Education Online https://www.drbeen.com/ Home - FLCCC | Front Line COVID-19 Critical Care Alliance https://covid19criticalcare.com/ References: Chronic Inflammation - StatPearls - NCBI Bookshelf https://www.ncbi.nlm.nih.gov/books/NBK493173/ Inflammation - Wikipedia https://en.wikipedia.org/wiki/Inflammation Cytokines and Chemokines at the Crossroads of Neuroinflammation, Neurodegeneration, and Neuropathic Pain - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753746/ Frontiers | Toll-Like Receptors, Associated Biological Roles, and Signaling Networks in Non-Mammals | Immunology https://www.frontiersin.org/articles/10.3389/fimmu.2018.01523/full Donate to the Front Line Covid-19 Critical Care Alliance, Inc. 
To educate medical professionals and the public in safe and effective ways to prevent and treat COVID-19. Click here to make a donation: https://frontlinecovid-19criticalcarealliance.salsalabs.org/donate/index.html Buy FLCCC gear: https://supportflccc.store/ Subscribe to our mailing list on our website: http://flccc.net/signup Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. Content Managed by ContentSafe.co

Long Story Short with Dr. Been Episode 10: Chronic Inflammation - Pathogen Elimination and Important Inflammatory Cytokines (Lecture 2) In this talk we will discuss how the inflammatory process is executed to contain microbes, repair tissue damage and to remove microbes, damaged tissue cells, worn out cells and irritants. We will look at: • Sentinel cells (mast cells, macrophages, neutrophils) and how these cells sense and ingest the microbes, damaged cells, or irritants and then destroy them • Important cytokines and chemokines, especially TNF, IL-1 and IL-6 • The process of respiratory burst or reactive oxygen species production in neutrophils • Reactive nitric oxide species in macrophages • Proteolytic enzymes The point of the above topics is to bring to light the mechanisms which, when dysregulated, play at the core of chronic inflammation. We will then discuss how various therapies target and modulate these mechanisms. Dr. Been: Medical Education Online https://www.drbeen.com/ Home - FLCCC | Front Line COVID-19 Critical Care Alliance https://covid19criticalcare.com/ References: Textbook: Abbas, Abul K.; Lichtman, Andrew H.; Pillai, Shiv. Cellular and Molecular Immunology E-Book (p. 94). Elsevier Health Sciences. Kindle Edition. URL list from Wednesday, May 25, 2022 Chronic Inflammation - StatPearls - NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK493173/ Inflammation - Wikipediahttps://en.wikipedia.org/wiki/Inflammation Cytokines and Chemokines at the Crossroads of Neuroinflammation, Neurodegeneration, and Neuropathic Pain - PMChttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753746/ Frontiers | Toll-Like Receptors, Associated Biological Roles, and Signaling Networks in Non-Mammals | Immunologyhttps://www.frontiersin.org/articles/10.3389/fimmu.2018.01523/full Role of nitric oxide in inflammatory diseases https://pubmed.ncbi.nlm.nih.gov/18236016/#:~:text=Nitric%20oxide%20(NO)%20is%20a,over%20production%20in%20abnormal%20situations. Donate to the Front Line Covid-19 Critical Care Alliance, Inc. 
To educate medical professionals and the public in safe and effective ways to prevent and treat COVID-19. Click here to make a donation: https://frontlinecovid-19criticalcarealliance.salsalabs.org/donate/index.html Buy FLCCC gear: https://supportflccc.store/ Subscribe to our mailing list on our website: http://flccc.net/signup Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. Content Managed by ContentSafe.co

Long Story Short with Dr. Been Episode 15: Reduced Risk of Long COVID from Omicron As Compared to Delta Zoe app study printed in the Lancet demonstrates that in some cases the risk of long COVID in the Omicron era is 76% less than the long COVID in the Delta era. Let's review the data. DrBeen: Medical Education Online https://www.drbeen.com/ Home - FLCCC | Front Line COVID-19 Critical Care Alliance https://covid19criticalcare.com/ URL list from Friday, Jul. 1 2022 Risk of long COVID associated with delta versus omicron variants of SARS-CoV-2 - The Lancet https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00941-2/fulltext#articleInformation Risk of long COVID associated with delta versus omicron variants of SARS-CoV-2 https://www.thelancet.com/action/showPdf?pii=S0140-6736%2822%2900941-2 Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. Content Managed by ContentSafe.co

Long Story Short with Dr. Been Episode 14: Brain Fog and Neurogenesis Neurogenesis is the process of the formation of new neurons, their maturity, and their integration into the brain circuits. Let's review what causes a disruption of neurogenesis and what the outcomes of reduced neurogenesis are. As the pandemic of neurological and neuropsychiatric issues continues to expand because of long COVID and vaccine injuries, it is important for us all to understand what lifestyle and diet changes may help combat the neurological deterioration and restore the neurogenesis process. DrBeen: Medical Education Online https://www.drbeen.com/ Home - FLCCC | Front Line COVID-19 Critical Care Alliance https://covid19criticalcare.com/ URL list from Thursday, Jun. 23 2022 You can grow new brain cells. Here's how | Sandrine Thuret - YouTube https://www.youtube.com/watch?v=B_tjKYvEziI A hypothalamic boost for neurogenesis | Nature Reviews Neuroscience https://www.nature.com/articles/s41583-022-00607-3 Robust adult neurogenesis in the primate hippocampus | Nature Neuroscience https://www.nature.com/articles/s41593-022-01075-9 Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior | Nature Neuroscience https://www.nature.com/articles/s41593-022-01065-x Single-nucleus sequencing finds no adult hippocampal neurogenesis in humans | Nature Neuroscience https://www.nature.com/articles/s41593-021-00991-6 Diet and depression: exploring the biological mechanisms of action | Molecular Psychiatry https://www.nature.com/articles/s41380-020-00925-x Stress and adolescent hippocampal neurogenesis: diet and exercise as cognitive modulators | Translational Psychiatry https://www.nature.com/articles/tp201748 Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus | Nature Neuroscience https://www.nature.com/articles/nn0399_266 Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus | Nature Neuroscience https://www.nature.com/articles/nn0399_266 Neurogenesis in the adult human hippocampus | Nature Medicine https://www.nature.com/articles/nm1198_1313 Professor Sandrine Thuret Dr. rer. nat. FHEA https://www.kcl.ac.uk/people/sandrine-thuret Sandrine Thuret: How Can Adults Grow New Brain Cells? : NPR https://www.npr.org/2021/03/05/973801760/sandrine-thuret-how-can-adults-grow-new-brain-cells Hippocampus in health and disease: An overview https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548359/#:~:text=Hippocampus%20is%20a%20complex%20brain,of%20neurological%20and%20psychiatric%20disorders. Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. Content Managed by ContentSafe.co

Long Story Short with Dr. Been Episode 12: Chronic Inflammation (Part 4) - T Regulatory Cells An important lecture in the chronic inflammation series that discusses T Regulatory cells (TRegs) and their function. Let's review this promising area of immunology. DrBeen: Medical Education Online https://www.drbeen.com/ Home - FLCCC | Front Line COVID-19 Critical Care Alliance https://covid19criticalcare.com/ References: Textbook: Abbas, Abul K.; Lichtman, Andrew H.; Pillai, Shiv. Cellular and Molecular Immunology E-Book (p. 94). Elsevier Health Sciences. Kindle Edition. A good reference diagram in this book: FIGURE 15.6 Mechanism of action of CTLA-4. A, Cytotoxic T lymphocyte antigen 4 (CTLA-4) expressed on regulatory T cells (Tregs) or activated T cells can inhibit the activation of responding T cells on the same antigen-presenting cells (APCs) (in trans). B, CTLA-4 on regulatory or activated T cells binds to B7 molecules on APCs and removes these molecules from the surface of the APCs, making the B7 co-stimulators unavailable to CD28 and blocking T cell activation. This action of CTLA-4 is able to suppress immune responses best when B7 levels are low, enabling CTLA-4 to out-compete the lower-affinity receptor CD28. URL list from Wednesday, May. 31 2022 Targeting IL-2: an unexpected effect in treating immunological diseases | Signal Transduction and Targeted Therapy https://www.nature.com/articles/s41392-017-0002-5#:~:text=While%20IL%2D2%20is%20generally,unwanted%20immune%20responses%20and%20eventually IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients - PubMed https://pubmed.ncbi.nlm.nih.gov/16304057/ IL-2 administration increases CD4+CD25hi Foxp3+ regulatory T cells in cancer patients - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1473973/ IL-10-Dependent Amelioration of Chronic Inflammatory Disease by Microdose Subcutaneous Delivery of a Prototypic Immunoregulatory Small Molecule - PubMed https://pubmed.ncbi.nlm.nih.gov/34305950/ Chronic Inflammation - StatPearls - NCBI Bookshelf https://www.ncbi.nlm.nih.gov/books/NBK493173/ Inflammation - Wikipedia https://en.wikipedia.org/wiki/Inflammation Cytokines and Chemokines at the Crossroads of Neuroinflammation, Neurodegeneration, and Neuropathic Pain - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753746/ Frontiers | Toll-Like Receptors, Associated Biological Roles, and Signaling Networks in Non-Mammals | Immunology https://www.frontiersin.org/articles/10.3389/fimmu.2018.01523/full Donate to the Front Line Covid-19 Critical Care Alliance, Inc. 
To educate medical professionals and the public in safe and effective ways to prevent and treat COVID-19. Click here to make a donation: https://frontlinecovid-19criticalcarealliance.salsalabs.org/donate/index.html Buy FLCCC gear: https://supportflccc.store/ Subscribe to our mailing list on our website: http://flccc.net/signup Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. Content Managed by ContentSafe.co

Long COVID and Chronic Fatigue Syndrome. And Endocrine Perspective. In an article published in December 2021 researchers curate the studies that indicate a possible disruption of suprarenal (adrenal glands) and the resultant chronic fatigue. Let's review their findings. URL list from Thursday, May. 6 2022 COVID-19 and chronic fatigue syndrome: An endocrine perspective - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641402/ Tissue expression of ACE2 - Summary - The Human Protein Atlas https://www.proteinatlas.org/ENSG00000130234-ACE2/tissue Post-acute COVID-19 syndrome - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893149/ COVID-19 and chronic fatigue syndrome: An endocrine perspective - ScienceDirect https://www.sciencedirect.com/science/article/pii/S2214623721000363#! Physiology, Cortisol - StatPearls - NCBI Bookshelf https://www.ncbi.nlm.nih.gov/books/NBK538239/ Adrenal Insufficiency (Addison's Disease) | Johns Hopkins Medicine https://www.hopkinsmedicine.org/health/conditions-and-diseases/underactive-adrenal-glands--addisons-disease Causes of Addison's disease: Adrenal gland disruption and others https://www.medicalnewstoday.com/articles/186235#surgery Donate to the Front Line Covid-19 Critical Care Alliance, Inc To educate medical professionals and the public in safe and effective ways to prevent and treat COVID-19. Click here to make a donation: https://frontlinecovid-19criticalcarealliance.salsalabs.org/donate/index.html Buy FLCCC gear: https://supportflccc.store/ Subscribe to our mailing list on our website: http://flccc.net/signup Content Managed by ContentSafe.co

How Polyethylene Glycol (PEG) in Vaccines May Cause Allergic Reactions PEG is an important part of the lipid nanoparticles based vaccines. Moderna COVID vaccine mRNA-1273 and Pfizer-Bio-n-Tech COVID vaccine BNT162b2 contain PEG2000 in abundance. Let's review why some people are getting allergic reactions with these vaccines, and the impact on the patient's immune system for the future PEGylated therapies. Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. URL list from Saturday, Apr. 30 2022 Polyethylene Glycol Immunogenicity: Theoretical, Clinical, and Practical Aspects of Anti-Polyethylene Glycol Antibodies | ACS Nano https://pubs.acs.org/doi/10.1021/acsnano.1c05922# Polyethylene glycol - Wikipedia https://en.wikipedia.org/wiki/Polyethylene_glycol Donate to the Front Line Covid-19 Critical Care Alliance, Inc To educate medical professionals and the public in safe and effective ways to prevent and treat COVID-19. Click here to make a donation: https://frontlinecovid-19criticalcarealliance.salsalabs.org/donate/index.html Buy FLCCC gear: https://supportflccc.store/ Subscribe to our mailing list on our website: http://flccc.net/signup Content Managed by ContentSafe.co

FLCCC Lecture 6 - Long COVID Symptoms Title: Characteristics of Long COVID: An International Cohort with 7 Months of Symptoms. Description In this episode, Dr. Mobeen Syed discusses a study in which researchers from the UK and US collected data to present long COVID symptoms, how prolonged the symptoms were and the impact they had on patients. This discussion sets the stage for us to understand the body's organ systems involved, and the diversity and scale of clinical presentation. In upcoming talks we will discuss the pathophysiology and management approaches. Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. URL list Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK - Office for National Statistics https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/prevalenceofongoingsymptomsfollowingcoronaviruscovid19infectionintheuk/7april2022 List of systems of the human body - Wikipedia https://en.wikipedia.org/wiki/List_of_systems_of_the_human_body Characterizing long COVID in an international cohort: 7 months of symptoms and their impact - eClinicalMedicine https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(21)00299-6/fulltext Characterizing long COVID in an international cohort: 7 months of symptoms and their impact https://www.thelancet.com/action/showPdf?pii=S2589-5370%2821%2900299-6 Multi-organ impairment and Long COVID: a 1-year prospective, longitudinal cohort study | medRxiv https://www.medrxiv.org/content/10.1101/2022.03.18.22272607v1 Frontiers | COVCOG 2: Cognitive and Memory Deficits in Long COVID: A Second Publication From the COVID and Cognition Study | Aging Neuroscience https://www.frontiersin.org/articles/10.3389/fnagi.2022.804937/full ----------------------- Formed by leading critical care specialists in March 2020, the Front Line COVID-19 Critical Care Alliance (FLCCC) has developed highly effective treatment protocols that aim to prevent and treat COVID-19 at all stages of the disease. We are a 100% donor-supported 501(c)(3) non-profit organization — our work would not be possible without you. Your gifts help us expand our reach and share the latest research available, for the health and well-being of all. To donate online, click here: https://covid19criticalcare.com/network-support/support-our-work/ To follow FLCCC, click here: https://covid19criticalcare.com/follow-flccc-2/ To learn more about our protocols, click here: https://covid19criticalcare.com/covid-19-protocols/ To buy FLCCC gear, click here: https://supportflccc.store/ Content Managed by ContentSafe.co

Long COVID Prevalence and Most Common Symptoms Let's review the prevalence of long COVID in the UK. We will extrapolate for the USA. And, we will also review a study from 2020 demonstrating long COVID in acute COVID patients. Finally, we will also review a study for the characteristics of long COVID in France. Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. URL list from Thursday, Apr. 14 2022 Course of post COVID-19 disease symptoms over time in the ComPaRe long COVID prospective e-cohort | Nature Communications https://www.nature.com/articles/s41467-022-29513-z Post-COVID syndrome in non-hospitalised patients with COVID-19: a longitudinal prospective cohort study - ScienceDirect https://www.sciencedirect.com/science/article/pii/S2666776221000995 Persistent Symptoms in Patients After Acute COVID-19 | Critical Care Medicine | JAMA | JAMA Network https://jamanetwork.com/journals/jama/fullarticle/2768351/ Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK - Office for National Statistics https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/prevalenceofongoingsymptomsfollowingcoronaviruscovid19infectionintheuk/7april2022 Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK - Office for National Statistics https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/prevalenceofongoingsymptomsfollowingcoronaviruscovid19infectionintheuk/1april2021 Long COVID and Long haulers | Coronavirus | UC Davis Health https://health.ucdavis.edu/coronavirus/covid-19-information/covid-19-long-haulers United Kingdom: Coronavirus Pandemic Country Profile - Our World in Data https://ourworldindata.org/coronavirus/country/united-kingdom United States: Coronavirus Pandemic Country Profile - Our World in Data https://ourworldindata.org/coronavirus/country/united-states Donate to the Front Line Covid-19 Critical Care Alliance, Inc To educate medical professionals and the public in safe and effective ways to prevent and treat COVID-19. Click here to make a donation: https://frontlinecovid-19criticalcarealliance.salsalabs.org/donate/index.html Buy FLCCC gear: https://supportflccc.store/ Subscribe to our mailing list on our website: http://flccc.net/signup Follow us on Telegram: https://t.me/FLCCC_Alliance Content Managed by ContentSafe.co

The Long Story Short with Dr. Been Epstein Barr Virus Reactivation in COVID Dr. Been reviewed a study from China published in May 2021 concluding a high incidence of EBV co-infection in COVID-19 patients. EBV/SARS-CoV-2 coinfection was associated with fever and increased inflammation. EBV reactivation may be associated with the severity of COVID-19. The reactivation of EBV may also be the cause of the COVID long haul symptoms. Original video from Dr. Been posted in August 2021 About infectious Mononucleosis: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670567/ Study published in nature on May 21st 202: https://www.nature.com/articles/s41598-021-90351-y Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. Content Managed by ContentSafe.co

The Long Story Short with Dr. Been Evidence of Epstein Barr Virus Reactivation in Long COVID Patients Dr. Been reviews a study published on June 17th 2021 that shows that 30% of COVID long-haul patients have EBV reactivation. He reviews the study and the evidence presented. Original video from Dr. Been posted in August 2021 Reference to the study:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233978/ Other studies supporting the evidence of EBV in COVID long-haul: https://pubmed.ncbi.nlm.nih.gov/28956548/ https://pubmed.ncbi.nlm.nih.gov/2987786/ https://pubmed.ncbi.nlm.nih.gov/231279/ Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. Content Managed by ContentSafe.co

The Long Story Short with Dr. Been Epstein Barr Virus (EBV) Serology Dr. Been reviews the serology of the Epstein Barr Virus (EBV). EBV causes Infectious Mononucleosis. This disease is usually benign and self limiting. However, in some cases it can become chronic, or reactivating. EBV can also cause cancers and other serious complications. Original video from Dr. Been posted in August 2021 About infectious Mononucleosis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670567/ CDC on EBV Serology https://www.cdc.gov/epstein-barr/laboratory-testing.html Serological diagnosis of Epstein-Barr virus infection: Problems and solutions https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782265/ The Relationship Between Environmental Factors and the Profile of Epstein-Barr Virus Antibodies in the Lytic and Latent Infection Periods in Healthy Populations from Endemic and Non-Endemic Nasopharyngeal Carcinoma Areas in China https://secure.jbs.elsevierhealth.com/action/cookieAbsent?code=null Epstein-Barr virus (EBV), Infectious Mononucleosis https://labpedia.net/epstein-barr-virus-ebv-infectious-mononucleosis/ High level overview of the serology States of a person: Susceptible to EBV (never had it before.) No antibodies Acute infection VCA IgM Acute infection late acute VCA-IgM and increasing VCA-IgG Past infection VCA-IgG and EBNA-1 IgG Reactivation of the EBV https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782265/High EA (D) IgG Increasing VCA-IgG Decreasing EBNA-1 IgG Even VCA-IgM may reappear during the reactivation Immunosuppressed may have Only EBVCA IgG without EBVCA IgM or EBNA-1 In 1.7% of the infected patients may only show EBNA-1 without EBVCA-IgG (this pattern is usually thought to be implausible.) Antibody patterns and causes from LabPedia https://labpedia.net/epstein-barr-virus-ebv-infectious-mononucleosis/ Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. Content Managed by ContentSafe.co

The Long Story Short with Dr. Been Epstein Barr Virus (EBV) - Long COVID Dr. Been reviews a study showing that the long-covid is associated with reactivated EBV. He provides an overview of EBV and infectious mononucleosis. Original video from Dr. Been posted in August 2021 ReferencesEBV and Mono on Wikipedia https://en.wikipedia.org/wiki/Epstein%E2%80%93Barr_virus https://en.wikipedia.org/wiki/Infectious_mononucleosis https://neurology.testcatalog.org/show/SEBV https://www.infectiousdiseaseadvisor.com/home/decision-support-in-medicine/infectious-diseases/epstein-barr-virus-ebv/ https://www.researchgate.net/figure/Dynamics-of-anti-EBV-antibody-responses-over-time-during-primary-infection_fig2_283439011 https://en.wikipedia.org/wiki/Reactive_lymphocyte Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. Content Managed by ContentSafe.co

Long Story Short with Dr. Been, Episode 3 - Persistent MRI Findings in Children After Pfizer Vaccine Myopericarditis. Seattle Children's Hospital In this study the researchers followed-up on children that had myocarditis from the second dose of the Pfizer-BionTech vaccine. Most of the abnormalities had resolved except that the abnormal strain persisted for the majority of the patients. Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. URL links: Persistent Cardiac MRI Findings in a Cohort of Adolescents with post COVID-19 mRNA vaccine myopericarditis - The Journal of Pediatrics https://www.jpeds.com/article/S0022-3476(22)00282-7/fulltext#relatedArticles Calculating Global Longitudinal and Circumferential Strains (GLS and GCS) https://www.semanticscholar.org/paper/Assessment-of-global-longitudinal-strain-using-a-Riffel-Keller/3c27b2ef65442245e8eb6a0a9efc3ef308c972f9/figure/2 Towards standardized postprocessing of global longitudinal strain by feature tracking – OptiStrain CMR-FT study | BMC Cardiovascular Disorders | Full Text https://bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-019-1255-4#:~:text=Left%20ventricular%20global%20longitudinal%20strain,among%20the%20users%20and%20vendors. GLOBAL LONGITUDINAL STRAIN AND GLOBAL CIRCUMFERENTIAL STRAIN IN RELATION TO LATE GADOLINIUM ENHANCEMENT IN CMR | Journal of the American College of Cardiology https://www.jacc.org/doi/10.1016/S0735-1097%2821%2902754-6 Strain imaging using cardiac magnetic resonance - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487809/ Assessment of global longitudinal strain using standardized myocardial deformation imaging: a modality independent software approach | Semantic Scholar https://www.semanticscholar.org/paper/Assessment-of-global-longitudinal-strain-using-a-Riffel-Keller/3c27b2ef65442245e8eb6a0a9efc3ef308c972f9 Global longitudinal strain is a more reproducible measure of left ventricular function than ejection fraction regardless of echocardiographic training | Cardiovascular Ultrasound | Full Text https://cardiovascularultrasound.biomedcentral.com/articles/10.1186/s12947-019-0168-9#:~:text=%2C%20Grenne%2C%20B.-,Global%20longitudinal%20strain%20is%20a%20more%20reproducible%20measure%20of%20left,fraction%20regardless%20of%20echocardiographic%20training. Global Longitudinal Strain for LV Function - American College of Cardiology https://www.acc.org/latest-in-cardiology/ten-points-to-remember/2018/08/10/11/01/assessment-of-left-ventricular-global-longitudinal-strain Late gadolinium enhancement | Radiology Reference Article | Radiopaedia.org https://radiopaedia.org/articles/late-gadolinium-enhancement-2?lang=us#:~:text=Late%20gadolinium%20enhancement%20is%20a%20result%20of%20regional%20differences%20in,and%20can%20be%20related%20to ________________________________________________________ Click here to make a donation: https://frontlinecovid-19criticalcarealliance.salsalabs.org/donate/index.html Buy FLCCC gear: https://supportflccc.store/ Subscribe to our mailing list on our website: http://flccc.net/signup Follow us on Telegram: https://t.me/FLCCC_Alliance Content Managed by ContentSafe.co