BEN BIKMAN h3 | Oxidative Stress when Glucose…glycation: kidney & heart disease; aging; Alzheimer’s

http://www.DoctorsToTrust.com
presents episode 2231 | Dr BEN BIKMAN w/Insuliniq.com

When blood sugar high, leads to over production of ROS...
-these are free radicals, this is oxidative stress
-a real problem: these are highly reactive, damaging
many things, from proteins in and out of cells, DNA,
lipids,
Even acute hyperglycemia leads to over production of ROS
because it overloads cell with energy
-at end of all metabolism, when using
mitochondria, electron transport system
is overwhelmed by high glucose,
harming ATP production

This is electron leakage...this gives birth to ROS
Study: 20 participants in 2 hour period: increased their
glucose to 15 mmol, had increase in blood plasma ROS
marker Went Through The Roof
-more oxidative stress can damage blood vessel directly
-PLUS altering lipoproteins

Dr Paul Reynolds: Advanced Glycation End Products [AGE]
-problematic, toxic products formed when glucose or
other simple sugars, like fructose, but not allulose...
Glucose molecule will irreversibly bind other molecules,
like proteins [amino acids] or fats or DNA or collagen
-which damages them
Glycation contributes to retinopothy,
kidney disease, atherosclerosis,
Alzheimers, aging--due to AGEs
becoming permanent, until broken down

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original video interview: https://youtu.be/7iOeWcYF6X4?si=rlHiBh5HD0vcAKae

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