Sequencing-based Approaches for Profiling DNA Methylation
DNA methylation plays an important and dynamic role in regulating gene expression. DNA methylation is essential for normal development and is associated with a number of key processes including genomic imprinting, X-chromosome inactivation, suppression of repetitive elements, and carcinogenesis.
Utilizing the highly trusted, proven DNA analysis platforms in the industry, CD Genomics will assist you in the epigenome wide association studies, combining the comprehensive, expert-selected coverage and high-throughput compatible with large sample size. https://www.cd-genomics.com/DNA-Methylation-Microarray-Service.html
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NP Genotyping Technologies
More about NP Genotyping Technologies can be reached at CD Genomics: https://www.cd-genomics.com/
Principle and Workflow of Whole Genome Bisulfite Sequencing - CD Genomics
Epigenetic studies have confirmed that DNA-methylation modification of specific gene regions plays an important role in chromosome conformation and gene expression regulation. Methylation of DNA cytosine residues at the C5 (5meC) is a common epigenetic mark in many eukaryotes and is widely found in CpG or CpHpG (H=A, T, C). There are mainly three approaches, including endonuclease digestion, affinity enrichment, and bisulfite conversion (Table 1). Almost all sequence-specific DNA methylation analysis approaches require a methylation-dependent treatment before amplification or hybridization to maintain fidelity. Various molecular biology techniques, such as next-generation sequencing (NGS), are subsequently performed to detect 5meC residues. https://www.cd-genomics.com/principles-and-workflow-of-whole-genome-bisulfite-sequencing.html
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The Development and Workflow of RNA-seq
CD Genomics has been providing the accurate and affordable RNA-Seq (RNA sequencing) service for decades. We combine both Illumina (short reads) and PacBio (long reads) platforms to obtain the transcriptome that allows de novo assembly or re-sequencing for bacteria, plants, animals and humans. https://www.cd-genomics.com/RNA-Seq-Transcriptome.html
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Bioinformatics Analysis of 16s rRNA Amplicon Sequencing Data
More information about bioinformatics analysis of 16s rRNA amplicon sequencing data can be reached at CD Genomics:
https://www.cd-genomics.com/
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Microbial Genomics
Until recently, the properties and compositions of the microbiota in the planet are still largely a black box. Next generation sequencing (NGS) has proven to be an invaluable tool for investigating diverse environmental and host-associated microbial communities, helping to generate enormous new data sets that can be mined for information on the composition and functional properties of vastly great numbers of microbial communities. https://www.cd-genomics.com/Microbial-Genomics.html
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Epigenetic Modifications & Epigenomic Technologies
Learn More About Epigenetic Modifications & Epigenomic Technologies at CD Genomics: https://www.cd-genomics.com/
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What is Metagenomics?
What is Metagenomics? You can learn more at CD Genomics: https://www.cd-genomics.com/Metagenomic-Shotgun-Sequencing.html
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What Is 16s rRNA sequencing?
Want to learn more about 16s rRNA sequencing, more information at https://www.cd-genomics.com/Full-Length-16S-18S-ITS-Amplicon-Sequencing.html
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Small RNA Sequencing the Challenge, Library Construction, and Bioinformatics
More about Small RNA Sequencing the Challenge, Library Construction, and Bioinformatics can be reached at CD Genomics: https://www.cd-genomics.com/
Methods and Workflow of Whole Genome Sequencing
More about Methods and Workflow of Whole Genome Sequencing can be reached at CD Genomics: https://www.cd-genomics.com/
Microsatellite Genotyping
More about Microsatellite Genotyping can be reached at CD Genomics: https://www.cd-genomics.com/