Ryu and Ken arrive in Barcelona, Spain to meet up with Chun-Li and her father Captain Dorai to attend a meeting with Interpol. Ryu and Ken were presented with awards for helping Dorai in apprehending the Asura. After that, Ryu, Ken and Chun-Li decide to go around Barcelona. They go to see a bull fight with one of the finest matadors around, Vega. Vega also is somewhat disturbingly interested in Chun-Li, but Chun-Li dislikes his methods of defeating a bull. That night, Vega sneaks into the hotel where Ryu, Ken and Chun-Li are staying, and appears right in Chun-Li's room and kisses her in her sleep. Ken then senses something in her room, wondering who that was.

Ryu and Ken try to stop the treasure hunters from stealing the artifact. But, the hunters tell Ryu and Ken to steal it for them, but they do not want to go in there without Dhalsim's permission, but Dhalsim tells them to go into the forbidden temple. But, as they enter the temple, Ryu and Ken are surrounded by mysterious smoke and are in some kind of strange place, just then, Ryu is faced by a giant living statue, and Ken is faced by another living statue. Ryu and Ken try to fight these statues, but no matter how hard Ryu and Ken fight, they can't defeat the statues. Ryu soon realizes that the statue is really Ken and they were fighting each other. Then, the smoke clears, and obtain the artifact. But, the hunters were not satisfied, but Dhalsim defeats the hunters and attends to Ryu and Ken's injuries.

Ryu and Ken head for India. They take a boat up the Ganges river, where they find a doctor with a makeshift hospital who is being harassed by some local people who want the hospital gone. Ryu and Ken help the doctor and then, with some of Ken's fortune, the doctor can build a better hospital. Ryu and Ken continue their journey up the river and find a village where Dhalsim lives. but, Dhalsim refuses to teach them about the "Ki". Then, a group of treasure hunters enter a forbidden temple to steal an ancient artifact, but they suspect that there is a monster that guards the treasure.

Ryu and Ken are still hot on the trail of the Ashura. Now, Captain Dorai comes to help Ryu and Ken. Then, Ryu and Ken were attacked by a sniper. They quickly escape and jump onto a back of a truck to infiltrate the hideout. Then, they are faced with the head of the Ashura. Ryu and Ken fight the leader and his henchmen and defeating them, and thus, down falling the Ashura for good. Then, Ryu meets Sagat who is now released from prison. Sagat finds out that Ryu is finding somebody who knows about the "Ki". Sagat tells Ryu and Ken to go to India to seek the one named, Dhalsim.

After Ryu defeated several prisoners, he is faced with a bug strong prisoner. He is Sagat, the former Muay Thai kick boxing champion. Sagat was not happy that Ryu defeated the prisoners. So, Ryu and Sagat fought. At first, Sagat had Ryu pinned down, then Ryu retaliated. Afgter the fight, Sagat tells Ryu on how he had it all, and why he was in prison, he as well as Ryu was set up by the Ashura. Meanwhile ,Ken finally finds the person who set up Ryu with the drugs. Then, Ryu was free from prison. Now, he helps Ken to defeat the Ashura.

Ryu and Ken are chasing down the Ashura. They have tracked them to Thailand. Unfortunately, no sooner that Ryu and Ken arrive in Thailand, Ryu is arrested for drug possession. Since there is no evidence that Ryu is innocent, Ryu was sent to prison, there he faced the warden, Nuchit. Meanwhile, Ken is trying to search for the man who set Ryu up with the drugs. Then Ryu gets into trouble with the other prisoners and fights with them. Ryu defeats the prisoners, but then, he will face a tough prisoner.

For several unrelenting days, Captain Dorai is hunting down a powerful underground drug ring known as "Ashura". Dorai has already arrested several Ashura members. Now, the Ashura are going to act revenge on Dorai. By doing so, they intend to kidnap his daughter, Chun-Li. One day after school, Chun-Li was spotted by a clown who tried to apprehend her, but, then fought back. Ryu and Ken soon joined to stop the criminals. The Ashura then tried to finish off Dorai at his own home, who was unknowingly waiting for them. Then, Ryu, Ken, Chun-Li and Fei-Long came to help him. They soon realize that some of the criminals are using a dangerous fighting art called "Muay Thai". But, they found a weak spot and finished off the Ashura, for now. Then, Ryu and Ken head for the southeast to discover more about Muay Thai.

It is another lazy Hong Kong day for Ryu, Ken and Chun-Li. This time, the 3 decide to go to Hong Kong's malls. Ken and Chun-Li were fascinated, but it easily bores Ryu. Then, Ryu spots an old man struggling to breathe, he aids the old man. Suddenly, a mysterious blue aura radiates from the old man's body, and just like that, the old man feels better. The old man decides to help Ryu, he tells him of a legend of a mystical energy called "Ki", and he even shows Ryu on how to perform a special fighting technique, though Ryu still does not believe in it. Then, he rejoins Ken and Chun-Li. With permission from her father, Chun-Li shows to Ryu and Ken that she is also a powerful fighter.

After escaping from Kowloon Palace, Ryu, Ken and Chun-Li decide to have an easy day in Hong Kong. First, they have breakfast. Then, Chun-Li suggested to go see her friend, the martial arts superstar Fei-Long, perform in his latest movie while it is in still production. To Ryu and Ken's surprise, Fei-Long decides to choose one of them in a fight scene in the movie. He chooses Ken. Then, they fight, and it turns out to be one of the best fight scenes ever shot.

Ryu, Ken and Chun-Li try to escape from Kowloon Palace. Then, they are being attacked by street fighters from all sides. So, they realize that they have to fight in order to survive. then, Chun-Li's father Captain Dorai, comes in to assist them.

Ryu and Ken take a trip to Hong Kong where their tour guide, Chun Li takes them to an underground fighting arena.

One day on makunai island (off the coast of Japan) Ryu receives a letter from his pen pal from the United States, Ken. It is an invitation for Ryu to come to meet Ken in San Francisco. Ryu accepts this invitation. When Ryu arrives in San Francisco, Ken picks him up and brings him to his house. Then, at night, Ken decides to scope San Francisco for bars, then Ken flirts with one of the air force pilots' girlfriends and gets into a fight. Ken defeats the pilot, but he and Ryu are unaware of their next opponent.

As Ken defeats an air force pilot in the bar, the pilot's commander going by the name of Guile steps in and sees what Ken has done. However, Ryu wants to have his turn at kicking butt. However, Guile dodges Ryu's attacks and defeats Ryu easily. Ken, angry and out for revenge on Guile, Ken searches every air force base to find Guile, Ken eventually finds him and confronts Guile. Unfortunately for Ken, he suffers the same fate as Ryu. Then, both Ryu and Ken realize that Guile is nothing like any of the opponents that they are use to fighting in karate tournaments, they quickly realize that Guile is a Street Fighter and does not follow any rules or codes while fighting. So, both Ryu and Ken decided to venture the world to learn the way of the Street Fighter. They are going to start in Hong Kong.