Believe M.E. (Horizon Episode for BBC Two) (1988) (Auphonic A.I. Sound Remaster)

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9 months ago
Health & Science

Original YouTube Video: https://youtu.be/8HW1SzHqMhs?si=zw6IiAiu32VyJxLg

"Believe M.E." 1988 BBC Horizon episode on the much maligned, misunderstood, medically ignorant, stigmatised "enteroviral" induced "neurological disease" "Epidemic" Myalgic Encephalomyelitis (M.E.) (aka Enteroviral Encephalomyelitis)

"Epidemic" Myalgic Encephalomyelitis (aka Enteroviral Encephalomyelitis) M.E.

https://www.me-pedia.org/wiki/Epidemic_myalgic_encephalomyelitis

Early Outbreaks of Epidemic Neuromyasthenia - Dr. Gordon Parish (1978)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2425322/

Postviral Fatigue Syndrome (renamed "Chronic Fatigue Syndrome") - 1994 Fukuda "CFS" criteria can overlap the onset of an "enteroviral infection", which may lead to a "persistent enteroviral infection" or "Limbic Encephalitis"

https://me-pedia.org/wiki/Postviral_fatigue_syndrome

Enterovirus

https://me-pedia.org/wiki/Enterovirus

Non-Cytolytic Enterovirus (persistent "Enteroviral" infection)

https://me-pedia.org/wiki/Non-cytolytic_enterovirus#:~:text=Cytolytic%20refers%20to%20destruction%20of,cells%20in%20which%20it%20resides.

Myalgic encephalomyelitis—a persistent enteroviral infection? - Elizabeth Dowsett, Melvin Ramsay (1990)

https://academic.oup.com/pmj/article/66/777/526/7061518?login=false

Selective Serotonin Reuptake Inhibitor Fluoxetine Inhibits Replication of Human Enteroviruses B and D by Targeting Viral Protein 2C - 10mg-a-day (Low-Dose) (2013)

https://journals.asm.org/doi/10.1128/aac.02084-12

The Myalgic Encephalomyelitis Dilemma - Dr. Irving Spurr (Invest In M.E.)

https://www.investinme.org/Article-280%20THE%20MYALGIC%20ENCEPHALOMYELITIS%20DILEMMA.shtml

A GP's experiences of treating "Enteroviral" induced PVFS (aka CFS - Limbic Encephalitis), "Epidemic" M.E. (aka Enteroviral Encephalomyelitis) & The Myalgic Encephalomyelitis Syndrome (persistent Enterovirus Infection) - Dr. Irving Spurr (Invest in M.E.)

https://youtu.be/FfSpAKvN5a8?si=DfXNN5a8chM8prqy

"Epidemic" Myalgic Encephalomyelitis (aka Enteroviral Encephalomyelitis) & Postviral Fatigue Syndrome (aka Encephalitis) Outbreaks

https://me-pedia.org/wiki/History_of_myalgic_encephalomyelitis_and_chronic_fatigue_syndrome

Concept of Myalgic Encephalomyelitis (M.E.) (1970) - A "smear attempt" of M.E. Patients as having a Psychological Condition or Function Disorder by Dr. Colin McEvedy & Dr. William Beard (both Psychiatrists) in order that patients, wouldn't be taken seriously by the medical profession, in order to suit Private Medical Insurance Providers

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1700895/

The clinical syndrome variously called Benign Myalgic Encephalomyelitis, Iceland Disease and Epidemic Neuromyasthenia - Donald Acheson (Chief Medical Officer of UK) (1959)

https://www.amjmed.com/article/0002-9343(59)90280-3/abstract

Benign Myalgic Encephalomyelitis - Donald Acheson (Chief Medical Officer of UK) (1957)

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(57)90999-6/fulltext

1955 Cumberland Outbreak - Wallis Study

https://me-pedia.org/wiki/1955_Dalston_outbreak

Investigation into an unusual disease seen in epidemic and sporadic form in a general practice in Cumberland in 1955 & subsequent years - Wallis

https://era.ed.ac.uk/handle/1842/9382

Chest Pain

https://me-pedia.org/wiki/Chest_pain

Lymphadenopathy (Swollen Lymph Nodes)

https://my.clevelandclinic.org/health/symptoms/15219-swollen-lymph-nodes

Myalgia

https://me-pedia.org/wiki/Myalgia#:~:text=It%20requires%20that%20%22there%20is,type%2C%20pattern%20or%20severity.%22

Neurocognitive Dysfunction

https://www.me-pedia.org/wiki/Cognitive_dysfunction#:~:text=Page%20actions&text=Cognitive%20dysfunction%20or%20cognitive%20impairment,patients%20call%20%22fibro%20fog.%22

Muscle Fatigability

https://me-pedia.org/wiki/Muscle_fatigability

Paresthesias (Numbness & Tingling in hands - Sensory distribution of nerves: Dorsal Ulnar Branch)

https://me-pedia.org/wiki/Paresthesia#:~:text=Paresthesia%20ia%20caused%20by%20disruption,caused%20by%20forms%20of%20neuropathy.

Muscle Fasciculations

https://me-pedia.org/wiki/Muscle_fasciculations#:~:text=Muscle%20fasciculations%20or%20muscle%20twitches,weak%20to%20move%20a%20limb.

Muscle Spasm

https://me-pedia.org/wiki/Muscle_spasm#:~:text=Muscle%20spasms%20or%20cramp%2C%20also,look%20hard%20under%20the%20skin.

1955 Royal Free Hospital Outbreak

https://me-pedia.org/wiki/1955_Royal_Free_Hospital_outbreak

Abortive Poliomyelitis

https://me-pedia.org/wiki/Abortive_poliomyelitis

1950 New York State Outbreak

https://me-pedia.org/wiki/1950_New_York_State_outbreak

Coxsackievirus

https://me-pedia.org/wiki/Coxsackievirus#:~:text=Coxsackie%20B%20viruses%20can%20sometimes,epidemic%20and%20sporadic%20myalgic%20encephalomyelitis

1948-49 Akureyri Outbreak

https://me-pedia.org/wiki/1948-49_Akureyri_outbreak

1934 Los Angeles Atypical Polio Outbreak

https://me-pedia.org/wiki/1934_Los_Angeles_atypical_polio_outbreak

Polio (Cleveland Clinic)

https://my.clevelandclinic.org/health/diseases/15655-polio

Featuring Jimmy Hood MP of Clydesdale, Scotland, Hilary McLennan (M.E. Patient), P.K. Thomas (Professor of Neurology, Arrogant, Medically Ignorant, Gaslighter, Patient Blamer & Disbelieving), Dr. Winifred Watson (Hilary McLennan's GP), Michael Mayne (M.E. Patient & Dean of Westminster), Molly Champion (M.E. Patient), Sheila Neal (Nurse at the Royal Free Hospital during the 1955 outbreak, who was struck by the virus), Dr. Melvin Ramsay (Infectious Diseases), Dr. Anthony Pelosi (CFS Psychiatrist & Patient Blamer), Dr. Len Achard (Senior Lecturer in Biochemistry), Professor James Mowbray (Professor of Immunopathology), Dr. Colin McEvedy (Psychiatrist & Misogynist), Jack Ashley MP of Stoke-on-Trent, Dr. William Weir (PVFS & M.E. Specialist)

Studies

Postviral Fatigue Syndrome: Persistence of Enterovirus RNA in Muscle and Elevated Creatine Kinase - L.C. Archard, PhD, N.E. Bowles, BSc, P.O. Behan, MD FRCP, E.J. Bell, PhD MRCPath, D Doyle, MD (1988)

https://journals.sagepub.com/doi/10.1177/014107688808100608?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

Derivation and Biochemical Characterization of an Enterovirus Group-Specific Monoclonal Antibody (1987)

https://karger.com/int/article-abstract/28/3/163/176768/Derivation-and-Biochemical-Characterization-of-an?redirectedFrom=fulltext

Original YouTube Video

https://m.youtube.com/watch?fbclid=IwAR1mHAb1F93Aup_VJtqQusR9rL_N0Sz3zBs97s5EnSvC-9GclnFuCf-I330&v=8HW1SzHqMhs&feature=youtu.be

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