Molecular Assassins: How Azoles Cause Fungal Pathogens to Self-Destruct

New research led by the University of Exeter shows that azole antifungals trigger self-destruction in fungal pathogens by inhibiting ergosterol production, potentially aiding efforts to combat fungal resistance and safeguard food and health.

Scientists have found that the world’s most commonly used class of antifungals causes pathogens to self-destruct. This discovery, led by the University of Exeter, could enhance methods to safeguard food security and protect human health.