Insulin Function Types | Synthesis , Secretion & Regulation | Diabetes
Insulin Function Types | Synthesis , Secretion & Regulation | Diabetes
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Insulin is synthesized as preproinsulin and processed to proinsulin. Proinsulin is then converted to insulin and C-peptide and stored in secretary granules awaiting release on demand. Insulin synthesis is regulated at both the transcriptional and translational level.
The major purpose of insulin is to regulate the body's energy supply by balancing micronutrient levels during the fed state [30]. Insulin is critical for transporting intracellular glucose to insulin-dependent cells/tissues, such as liver, muscle, and adipose tissue.
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