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Spinal cancer is one of the most common secondary cancers and, if not treated within 24 hours, can lead to double incontinence, paralysis and death in just 30 days. The BBC has been given exclusive access to a specialist service in the UK, which is working to extend patients' lives, giving people extra months for final holidays and proper goodbyes.

Russia's unmanned Luna-25 spacecraft has crashed into the Moon after spinning out of control. It was Russia's first Moon mission in almost 50 years. The craft was designed to be the first ever to land on the Moon's south pole, but failed after encountering problems as it moved into its pre-landing orbit. It was set to explore a part of the Moon which scientists think could hold frozen water and precious elements. Roscosmos, Russia's state space corporation, announced that it had lost contact with the Luna-25 and believed the craft had "ceased to exist as a result of a collision with the surface of the Moon”. The loss of Luna-25 is a blow to Roscosmos. Russia's civilian space programme has been in decline for several years, as state funding is increasingly directed towards the military. Clive Myrie presents BBC News at Ten reporting by Will Vernon

A court in Pakistan has ordered that former Prime Minister Imran Khan should be held in jail for at least another two weeks. Mr Kahn has been in jail since he was sentenced to three years in prison at the start of August. That sentence has been suspended, but he is also facing charges under another case which was brought in the country's official secrets act

There has been a dramatic rise in Ukraine's number of dead, according to new estimates by unnamed US officials. Ukraine gives no official toll of its war dead - the figures remain classified. But US officials, quoted by the New York Times, recently put the number at 70,000 dead and as many as 120,000 injured.