benniegeorge's Videos

knockout cell lines24s

knockout cell lines

Creative Biogene is offering a series of gene knockout cell lines developed by CRISPR/Cas9 system. These cell lines provide you with a convenient means to study gene functions.

Yeast Expression System36s

Yeast Expression System

Yeast expression system is the most economical eukaryotic expression system for both secreted and intracellular proteins. Yeast expression system possesses the advantages of both prokaryotic and eukaryotic expression systems, such as high expression level, low cost, easy to scale up and proper protein folding which make it suitable for both small and large scale production of interested proteins.

Yeast Two-hybrid cDNA Library36s

Yeast Two-hybrid cDNA Library

Yeast two-hybrid cDNA library is a powerful molecular biology tool in studying the protein interactions, to find the domain that plays a key role in protein-protein interaction or to discover a new protein interaction with target proteins.

Baculovirus Service30s

Baculovirus Service

Baculoviruses are arthropod-specific viruses containing large double-stranded circular DNA genomes of 80,000–180,000 bp. In recent years, they have been utilized for producing complex eukaryotic proteins in insect cell cultures. There are several benefits of using baculovirus to express target protein, such as the virus being able to package large inserts, ability of post-translational modifications, enhanced protein folding and function, high expression levels and safety. Creative Biogene offers a wide range of baculovirus services to meet your needs. Creative Biogene can provide you with the best research materials and support in the baculovirus field.

Retrovirus Service36s

Retrovirus Service

Retroviral vectors are engineered to transfer and integrate target genetic material into the genomes of host cells. Retroviruses have several distinct advantages over other vectors, especially when permanent gene transfer is the preferred outcome.

Nuclear Receptor Screening36s

Nuclear Receptor Screening

Nuclear receptors (NRs) are a class of proteins responsible for sensing steroid and thyroid hormones and certain other molecules. There are 48 genes in the human genome that code for the NRs. The myriad molecular pathways modulated by NRs including but not limited to inflammation, lipid metabolism, apoptosis, extracellular matrix regulation, energy metabolism, and angiogenesis. These pathways’ processes can impact human health, such as general homeostasis, growth, and proliferation, which enable NRs to become the important therapeutic targets in the pathology of cancer, inflammation, and many other diseases for decades.

Gene Expression36s

Gene Expression

Protein production is a biotechnological process of generating specific proteins. It is typically achieved by the manipulation of gene expression in an organism such that it expresses large amounts of a recombinant gene. The process includes the transcription of the recombinant DNA to messenger RNA (mRNA), the translation of mRNA into polypeptide chains, which are ultimately folded into functional proteins and may be targeted to specific subcellular or extracellular locations. Recombinant proteins are widely used in the life science, biotechnology and medicine and can be achieved by cell-based or cell-free systems.

AAV Service24s

AAV Service

Adeno-associated virus (AAV) has been widely used by scientists to deliver exogenous genetic material into cultured cells or live animal models. AAV can infect both dividing and non-dividing cells. Multiple AAV serotypes (AAV-1, AAV-2, AAV-3, AAV-4, AAV-5, AAV-6, AAV-8, AAV-9, AAV-DJ/8 and AAV-DJ) enable AAVs to efficiently infect with broad specificity.

Ion Channel Cell Line25s

Ion Channel Cell Line

Creative Biogene offers an integrated custom service, starting with gene synthesis through to generation of ion channel stable cell lines and cell-based ion channel assays.

Improve Data Productivity with STR service43s

Improve Data Productivity with STR service

Creative Bioarray STR profiling is critical for verifying the identity of human cell lines, ensuring uniqueness of the cell line and detecting laboratory errors such as misidentification and cross-contamination of lines. The sensitivity and high power of discrimination makes our STR analysis an ideal choice for the various types of cell authentication.

The Relationship Between Telomerase and Tumor1m19s

The Relationship Between Telomerase and Tumor

Every study is different and requires different cells and samples. Creative Bioarray has the largest selection of organ specific and cancer related tumor cells available. Every sample has its own description and origin included so you know exactly what you are receiving with us.

How New-found Stem Cell Helps Regenerate Lung Tissue51s

How New-found Stem Cell Helps Regenerate Lung Tissue

The development of the lung is an evolutionary adaption to life on land. In order to survive on land, the lungs are necessary for most large animals. Its complex structure is partly determined by its integration with the cardiovascular system, which makes it an attractive organ that is difficult to study from a perspective of regenerative medicine.

Human Cardiac Stromal Cells24s

Human Cardiac Stromal Cells

Human cardiac stromal cells are derived from whole hearts that have been dissociated into single cells and cultured using differential adhesion. Human cardiac stromal cells are from a single donor. Human cardiac stromal cells may be used for various types of in vitro, in vivo, or transplantation studies into normal or diseased systems. In addition, they may be used in cardiovascular developmental studies.

Human Hepatocytes | Creative Bioarray23s

Human Hepatocytes | Creative Bioarray

HH are isolated from human liver. HH are cryopreserved immediately after purification and delivered frozen. Each vial contains >1 x 10^6 cells in 1 ml volume. HH are characterized by immunofluorescent method with antibodies to albumin, cytokeratin-18 and vimentin. HH are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HH is not recommend for expanding or long term cultures since the cells do not proliferate in culture.

Cytokines & Growth Factors24s

Cytokines & Growth Factors

Epidermal growth factor (EGF) is prototypic of a family of growth factors that are derived from membrane-anchored precursors. All members of this family are characterized by the presence of at least one EGF structural unit in their extracellular domain. The EGF structural unit is defined by the presence of a conserved six-cysteine motif that forms three disulfide bonds. EGF is initially synthesized as a 130 kDa precursor transmembrane protein containing nine EGF units.

Primary fibroblasts44s

Primary fibroblasts

Fibroblasts, the most common mammalian connective tissue cells, are specialized for the secretion of collagenous extracellular matrix and are jointly responsible for the architectural framework of the body. A fibroblast cell plays a critical role in wound healing. When a tissue is injured, the fibroblasts nearby proliferate, migrate into the wound, and produce large amounts of collagenous matrix, which helps to isolate and repair the damaged tissue.

Custom Probes24s

Custom Probes

Creative Bioarray is pleased to announce the introduction of custom labeled Fluorescence in situ Hybridization (FISH) Probes for a range of molecular and cytogenetic applications. What sets us apart in custom labeled probe manufacturing is our ability to consistently offer high quality locus-specific probes that can be customized to meet the specific needs of researchers and clinicians alike.

Bone Marrow Mononuclear Cells24s

Bone Marrow Mononuclear Cells

Bone Marrow-Mononuclear Cells are isolated by diluting bone marrow with phosphatebuffered saline and using density gradient separation techniques. After centrifugation, the Mononuclear Cells layer is collected. Mononuclear Cells can be processed further to isolate various subpopulations.

Human Nervous Cells46s

Human Nervous Cells

The nervous system is responsible for sending, receiving and interpreting signals from all over the body and coordinates its action. It processes and intergrates information on a variety of levels, and directs the body to respond appropriately. The nervous cell system consists of neurons, endothelial cells, pericytes, smooth muscle cells, fibroblasts, Schwann cells, epithelial cells, meningeal cells and microglia.

HDF adult24s

HDF adult

HDF-a are isolated from adult human skin. HDF-a are cryopreserved at primary culture and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. HDF-a are characterized by their spindle morphology and immunofluorescent method with antibody to fibronectin. HDF-a are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HDF-a are guaranteed to further expand for 15 population doublings at the condition provided by Creative Bioarray.

Adult Stem Cells24s

Adult Stem Cells

Adult stem cells are undifferentiated cells, found throughout the body after development that multiply by cell division to replenish dying cells and regenerate damaged tissues. Also known as somatic stem cells, they can be found in juvenile as well as adult animals and human bodies. Creative Bioarray provides adult stem cells from various tissue/organs of human, mouse and rat.

endothelial cell medium30s

endothelial cell medium

Primary endothelial cells are commonly used in developmental and disease mechanisms studies. Endothelial cells are phenotypically characterized as CD31+, KDR+, and vWF+ cells. The endothelial cell medium products at Creative Bioarray are specially designed to support the growth of different types endothelial cells and have been tested for its ability to support CD31+, KDR+, and vWF+ human endothelial cells growth in vitro. Our medium systems have been specifically developed and optimized for various endothelial cell types of human, mouse, rat, porcine, bovine, monkey, canine, etc.

Fluorescent In Situ Hybridization24s

Fluorescent In Situ Hybridization

Fluorescence in situ hybridization (FISH), developed in 1980s, is a cytogenetic technique using fluorescent probes to bind the chromosome with a high degree of complementarity. It is a powerful and easy method to detect RNA or DNA sequences in cells, tissues and tumors. This technique is useful for identifying chromosomal abnormalities, gene mapping, characterizing somatic cell hybrids, checking amplified genes and studying the mechanism of rearrangements. RNA FISH is used to measure and localize mRNAs and other transcripts within tissue sections or whole mounts.

Hep-3b cells24s

Hep-3b cells

Established from the tumor tissue of an 8-year-old black boy in 1976.The cells contain a 2.3 kb integrated hepatitis B virus genome fragment. However there is currently no evidence that this cell line produces infectious Hepatitis B virus. Cells were described to produce a variety of proteins, e.g. alpha-fetoprotein, albumin, transferrin, alpha2-macroglobulin, alpha1-antitrypsin, haptoglobin and others.