Stem Cell
Identification and characterization of stem cells are difficult and often evolving. A healthy and robust stem cell population always lack specific markers, while stem cells must display the appropriate markers in order to characterize them.
https://www.creative-bioarray.com/services/stem-cell-research.htm
Angiogenesis Assay
Angiogenesis, a pivotally natural process in the development of cancer malignancy, is a key step in the tumor progression towards an aggressive, metastatic state with poor response to therapies. A well-established vascular network allows tumors to overcome growth restrictions of hypoxia and nutrient deprivation and provides paths for tumor cell dissemination. During the process of angiogenesis, endothelial cells are activated, and recruited.
https://www.creative-bioarray.com/3D-Angiogenesis-Assay.htm
Cell cycle regulation
Cell cycle refers to the set of events through which a cell grows, replicates its genome, and ultimately divides into two daughter cells through the process of mitosis.
https://www.creative-bioarray.com/cell-cycle-assays.htm
keratinocyte growth | Creative Bioarray
Keratinocyte Growth Medium-2 has been optimized for the proliferation of keratinocytes in a serum-free environment and typically provides higher growth rates than Keratinocyte Growth Medium Medium.
https://www.creative-bioarray.com/SuperCult%C2%AE-Keratinocyte-Growth-Medium-Supplement-Kit-2-CM-1442L-item-40366.htm
Hepatocytes | Creative Bioarray
HH are isolated from human liver. HH are cryopreserved immediately after purification and delivered frozen. Each vial contains >1 x 10^6 cells in 1 ml volume. HH are characterized by immunofluorescent method with antibodies to albumin, cytokeratin-18 and vimentin. HH are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HH is not recommend for expanding or long term cultures since the cells do not proliferate in culture.
https://www.creative-bioarray.com/Human-Hepatocytes-CSC-C1495-item-39332.htm
Cell Proliferation Assay
Measure of cell proliferation based on the metabolic activity of a population of cells can be used. Tetrazolium salts or Alamar Blue are compounds which become reduced in the environment of metabolically active cells, forming a formazan dye that subsequently changes the color of the media, which is caused by increased activity of the enzyme lactate dehydrogenase during proliferation. The absorption of the media-containing dye solution can be read using a spectrophotometer or microplate reader in low- or high-throughput configurations.
https://www.creative-bioarray.com/Services/cell-proliferation-assay-services.htm
Tumor Cell
Creative Bioarray provides a wide range of high quality normal human and animal cells, cell culture medium and reagents, FISH probes, tissue arrays, microorganisms and equipments. In addition, we also offer series of related services including cell services, biosample services and histology services for the researcher to make their project better and faster.
https://www.creative-bioarray.com/products/tumor-cell-types-13.htm
Stem Cells
Mesenchymal stem cells (MSC) are well-characterized population of adult stem cells. They have the potential to develop into mature cells that produce fat, cartilage, bone, tendons, and muscle. These properties in combination with their developmental plasticity have generated tremendous interest in the potential use of mesenchymal stem cells to replace damaged tissues.
https://www.creative-bioarray.com/products/adult-stem-cells-34.htm
Mouse Tumor Cells
Species: human, Caucasian female 69 years old;
Tissue: breast;
Tumor: adenocarcinoma;
Transfected with pBact, expression vector under control of the human beta actin promotor, resistant to G418S.;
Original line: MCF7;
Derived from: pleural effusion
https://www.creative-bioarray.com/products/tumor-cell-types-13.htm
Gastrointestinal Cells
The gastrointestinal system processes food for energy and rids the body of solid waste. After food is chewed and swallowed, it enters the esophagus, a tube that carries food through the neck and chest to the stomach. When the gastrointestinal cells grow out of control, the gastrointestinal cancer starts such as gastrointestinal stromal tumors and carconoid tumors. The gastrointestinal cells from Creative Bioarray are isolated from human tissue.
https://www.creative-bioarray.com/Products/Gastrointestinal-Cells-list-141.htm
Analytical Testing Service
Analytical testing service is a deep analysis of samples through biological, chemical and physical method or with high-tech instruments.
Cell Apoptosis Assays
Apoptosis is considered a vital component of various processes including normal cell turnover, proper development and functioning of the immune system, hormone-dependent atrophy, embryonic development and chemical-induced cell death. Inappropriate apoptosis is a factor in many human conditions including neurodegenerative diseases, ischemic damage, autoimmune disorders and many types of cancer.
https://www.creative-bioarray.com/cell-apoptosis-assays.htm
Custom Viral Service
Viral vectors are a tool commonly used by molecular biologists to deliver genetic material into cells. This process can be performed inside a living organism (in vivo) or in cell culture (in vitro). Though a number of viruses have been developed, interest has centered on four types: retrovirus, lentivirus, adenovirus and adeno-associated virus (AAV).
https://www.creative-biogene.com/Services/Custom-Viral-Service
The Heterogeneity of Tumor Cell
Creative Bioarray consistently attains the highest standards and uses the most reliable procedures to verify every cell line.
https://www.creative-bioarray.com/products/tumor-cell-types-13.htm
ABC transporters Screening
Creative Biogene offers a wide range of ABC transporters assays, including P-gp (MDR1/ABCB1), BCRP (ABCG2) and BSEP (sPgp/ABCB11), etc. P-gp, BCRP and BSEP are highly expressed in the luminal membrane of enterocytes, endothelial cells in the brain, the border membrane of renal proximal tubules and canalicular membrane of hepatocytes.
https://www.creative-biogene.com/Services/Drug-Discovery-Services/ABC-transporters-Screening-and-Profilin-Assays.html
cell therapy
Oncologists are aimed at improving patients' survival and preventing new cases of the disease by investigating the mechanism and developing new treatment methods. The key programs include pioneering improvements in early detection, accurate diagnosis, meaningful prognosis, and more effective treatments.
Histology Services
Histology, the study of the microscopic anatomy of cells and tissues of plants and animals, commonly performed by examining cells and tissues under the microscope. It is frequently used in clinical research and basic research. Moreover, it is also an important tool in study of pathology. By using the specific antibody to bind the antigens, expression of antigens could be detected for diagnosis of disease, investigation of pathology, and localization of proteins.
https://www.creative-bioarray.com/Services/Histology-Services.htm
knockout cell lines
Creative Biogene is offering a series of gene knockout cell lines developed by CRISPR/Cas9 system. These cell lines provide you with a convenient means to study gene functions.
https://www.creative-biogene.com/Product/Gene-Knockout-Stable-Cell-Lines.html
Yeast Expression System
Yeast expression system is the most economical eukaryotic expression system for both secreted and intracellular proteins. Yeast expression system possesses the advantages of both prokaryotic and eukaryotic expression systems, such as high expression level, low cost, easy to scale up and proper protein folding which make it suitable for both small and large scale production of interested proteins.
https://www.creative-biogene.com/Services/Yeast-expression-systems-Pichia-pastoris.html
Yeast Two-hybrid cDNA Library
Yeast two-hybrid cDNA library is a powerful molecular biology tool in studying the protein interactions, to find the domain that plays a key role in protein-protein interaction or to discover a new protein interaction with target proteins.
https://www.creative-biogene.com/Services/Yeast-two-hybrid-cDNA-Library-Construction-Service
Baculovirus Service
Baculoviruses are arthropod-specific viruses containing large double-stranded circular DNA genomes of 80,000–180,000 bp. In recent years, they have been utilized for producing complex eukaryotic proteins in insect cell cultures. There are several benefits of using baculovirus to express target protein, such as the virus being able to package large inserts, ability of post-translational modifications, enhanced protein folding and function, high expression levels and safety. Creative Biogene offers a wide range of baculovirus services to meet your needs. Creative Biogene can provide you with the best research materials and support in the baculovirus field.
https://www.creative-biogene.com/services/Custom-Viral-Service/baculovirus-service.html
Retrovirus Service
Retroviral vectors are engineered to transfer and integrate target genetic material into the genomes of host cells. Retroviruses have several distinct advantages over other vectors, especially when permanent gene transfer is the preferred outcome.
https://www.creative-biogene.com/Services/Custom-Viral-Service/Retrovirus-service.html
Nuclear Receptor Screening
Nuclear receptors (NRs) are a class of proteins responsible for sensing steroid and thyroid hormones and certain other molecules. There are 48 genes in the human genome that code for the NRs. The myriad molecular pathways modulated by NRs including but not limited to inflammation, lipid metabolism, apoptosis, extracellular matrix regulation, energy metabolism, and angiogenesis. These pathways’ processes can impact human health, such as general homeostasis, growth, and proliferation, which enable NRs to become the important therapeutic targets in the pathology of cancer, inflammation, and many other diseases for decades.
https://www.creative-biogene.com/Services/Drug-Discovery-Services/Nuclear-Receptor-Screening-Assays.html
Gene Expression
Protein production is a biotechnological process of generating specific proteins. It is typically achieved by the manipulation of gene expression in an organism such that it expresses large amounts of a recombinant gene. The process includes the transcription of the recombinant DNA to messenger RNA (mRNA), the translation of mRNA into polypeptide chains, which are ultimately folded into functional proteins and may be targeted to specific subcellular or extracellular locations. Recombinant proteins are widely used in the life science, biotechnology and medicine and can be achieved by cell-based or cell-free systems.
https://www.creative-biogene.com/Services/Gene-expression-service.html
AAV Service
Adeno-associated virus (AAV) has been widely used by scientists to deliver exogenous genetic material into cultured cells or live animal models. AAV can infect both dividing and non-dividing cells. Multiple AAV serotypes (AAV-1, AAV-2, AAV-3, AAV-4, AAV-5, AAV-6, AAV-8, AAV-9, AAV-DJ/8 and AAV-DJ) enable AAVs to efficiently infect with broad specificity.
https://www.creative-biogene.com/Services/Custom-Viral-Service/AAV-service.html