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Logan/Wolverine becomes embroiled in the conflict between two groups of mutants: the X-Men, led by Professor Charles Xavier (played by Patrick Stewart), who believe in peaceful coexistence between mutants and humans, and the Brotherhood of Mutants, led by Magneto (played by Ian McKellen), who advocate for mutant supremacy over humans. Magneto has developed a device that can turn humans into mutants, and he plans to use it on world leaders during a summit on Ellis Island, with the intention of proving that mutants are the next stage of human evolution. The X-Men, including Cyclops (played by James Marsden), Jean Grey (played by Famke Janssen), and Storm (played by Halle Berry), must stop Magneto's plan and prevent a potentially catastrophic war between mutants and humans.