50 PERIODISTAS A SUELDO Y MEDIOS DE DIFUSIÓN. SÁNCHEZ MELGAR AMENAZA AL JUEZ PRESENCIA
50 PERIODISTAS A SUELDO Y MEDIOS DE DIFUSIÓN. SÁNCHEZ MELGAR AMENAZA AL JUEZ PRESENCIA
Del canal https://www.youtube.com/c/SantiagoRoyuelaSamit
Santiago Royuela Samit
Expediente Royuela
https://www.acodap.com/denuncias/
Adelante y difusión
The Spanish Deep-State : The Good Guys.
Who is the Judge Presencia:
"Remember, we are all in debt with him, he was behind the dación en pago (deed-in-lieu of foreclosure) in our country.
It had to be a judge, who would call out the irregularities in the Spansih courts.
There is no democracy in Spain, it is just a fiction".
From https://www.acodap.com/por-que-ayudar-al-juez-fernando-presencia/
********
"Why is it important to help the Judge Presencia":
https://www.youtube.com/watch?v=Lsg5ENnFoRU
********
Deed-in-lieu of foreclosure = Dación en pago
What is a deed-in-lieu of foreclosure:
A deed in lieu of foreclosure is a potential option taken by a mortgagor, or homeowner, usually as a means of avoiding foreclosure.
From: https://www.consumerfinance.gov/ask-cfpb/what-is-a-deed-in-lieu-of-foreclosure-en-291/
********
Insolvency proceedings = Concurso de acreedores
An insolvency proceeding is a judicial procedure that takes place when a person or company is unable to meet its outstanding payments, i.e. when it is unable to pay its debts.
From: https://economipedia.com/definiciones/concurso-de-acreedores.html
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Bad Bank:
A bad bank is a bank set up to buy the bad loans and other illiquid holdings of another financial institution.
The entity holding significant nonperforming assets will sell these holdings to the bad bank at market price.
By transferring such assets to the bad bank, the original institution may clear its balance sheet.
From: https://www.investopedia.com/terms/badbank.asp
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PIG:
PIG is a Spanish acronine used for some European and no European countries.
When it is about the southern economic countries. Such as Portugal, Italy, Greece and Spain.
From: https://economipedia.com/definiciones/paises-pigs.html
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Sareb:
Sareb was created in 2012 to manage and sell the toxic products received of the financial institutions that have received public subventions.
From: https://www.sareb.es/
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Luis de Guindos:
Vice-President for the central European bank and former minister for economic, industry and competitivity in Spain.
From: https://es.wikipedia.org/wiki/Luis_de_Guindos
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This footage is a short from en extense interview leaded by Rafael Navarro, cop225 to the Judge Presencia.
Full interview in: http://cop225.com/videos/2022/2022-03-21_-_Entrevista_con_el_magistrado_Fernando_Presencia_-_Poniendo_patas_arriba_la_judicatura-(w).mp4
Spanish Deep-State / Subtitles
The so called Expediente Royuela, the Royuela file, is a enourous amount of information,
mostly writen notes, between hign level politicians, judges, criminals, and law enforcement members,
that configure
a criminal organization and sustains itself, through hitcontracts, drug money, money landring, spying,
crime covering,
influence peeding, riged sentences...
- The writing notes have been intercepted by a net of informers, people in different fields of the society,
that per chance or position, have been able to provide this information. People who may or may not, be patriots,
but at the end, did feel the need to expose this criminal organization.
- Alberto Royuela, the father of the family, has been able to gather and store all the data, for more
than 20 years.
- The written notes have been copied and transcribed, and more that 200 lawsuits have been filed
- The written notes are proofs to be dismissed or confirmed in a cour of law by graphologists,
but they are not been processed.
- The Royuela family shows proof of more than 1700 killing in spanish soile.
- One of the main differences between the government's secret operations, and the Royuela file,
is that the targets here,
are not always criminals or terrorists, but civilians as well.
People who have not complied with the requirments of the spanish deep state, people who were fighting for
freedom and truth,
their families and friends,
or people who just happend to be in the wrong place at wrong time.
- Besides the criminal activity that enriches and protects the organization, missions are "requested"
by at least one foreign structure,
mostly, the Masonic Logia of Miami.
- The Royuela family has been calling out the criminal organization, suffered retaliations, a family
member , Javier Royuela Samit was killed,
Alberto spent about 18 monts in prison, and Santiago spent ten years.
- Since 2019, Santiago has been publishing the information, the writen notes and the lawsuits filed,
however,
no judge has been brave enough to conduct trials, the lawsuits have been archived.
- The only brave judge that has been helping the cause has suffered a forced exile from his position,
the judge Fernando Presencia.
- The royuela family has been defying authorities, but never been prosecuted for their claims.
- If Santiago and Alberto are lying, if the proofs are fake, how is it that none of the accused are
suiting them back?
What would happen if you were innocent and somebody would make fals claims againt you ?
would nt you suit them back and called them out?
- The information is spreading everywere, it is impossible to stop, that is why the damage control
policy has been to blame the Pegasus software filtrations.
- Some names that appear in the large ammount of notes, are the former president of Spain,
José-Luis Rodriguez Zapatero, the current defense minister, Margarita Robles,
the chief Prosecutor, Dolores Delgado, formers Prosecutor Carlos Jiménez Villarejo
and the chief of the high court of justice of Cataluña, José María Mena Álvarez...
- Now the story has taken an imprecedent turn, just a few days ago, Santiago has published
what is suppose to be,
the tombs of more that 40 people killed by the organization, and he is claming the the bodies
are buried in the warehouse
land, address Calle del Trueno nº 70, Leganés.
- Some people have alreaydy set camp in front of the warehouse, to make sure the bodies
are not moved out so no more covering should happen.
- May 19, 2022, Pedro Rossillo, youtube channel "El Arconte", went with his friend Carlos,
to the police station of Leganés, with the intention to present the proofs of
the Calle del Trueno nº 70, Leganés tombs, he is then beein tolled that there were no need for a new statement,
as they were aware of it already.
As he insisted to make his own statemant, a police officer told him :
If you are recoding with your phone, I would throw it out of the window,
and I ll throw you out of the window as well.
Pedro called out this threat to another 5 or 6 police officers who were just there,
but they said that their collegue talked about his phone, and did not t
Pedro wanted to make present a complaining against the police officer,
but then, the rest of the police officer started to put on their gloves, as they surounded both Pedro
and his friend Carlos.
At this point, knowing that the spanish police has the presuntion of truth,
they could have beating up and being accused of starting a fight wihtin the police station.
Funy enough, we have recently knew, that the police station received a suprise visit just a
day or so before that,
The current, home office minister: Fernando Grande-Marlaska.
https://www.youtube.com/c/SantiagoRoyuelaSamit
73
views
1
comment
Expediente Royuela
The so called Expediente Royuela, the Royuela file, is a enourous amount of information,
mostly writen notes, between hign level politicians, judges, criminals, and law enforcement members,
that configure
a criminal organization and sustains itself, through hitcontracts, drug money, money landring, spying,
crime covering,
influence peeding, riged sentences...
- The writing notes have been intercepted by a net of informers, people in different fields of the society,
that per chance or position, have been able to provide this information. People who may or may not, be patriots,
but at the end, did feel the need to expose this criminal organization.
- Alberto Royuela, the father of the family, has been able to gather and store all the data, for more
than 20 years.
- The written notes have been copied and transcribed, and more that 200 lawsuits have been filed
- The written notes are proofs to be dismissed or confirmed in a cour of law by graphologists,
but they are not been processed.
- The Royuela family shows proof of more than 1700 killing in spanish soile.
- One of the main differences between the government's secret operations, and the Royuela file,
is that the targets here,
are not always criminals or terrorists, but civilians as well.
People who have not complied with the requirments of the spanish deep state, people who were fighting for
freedom and truth,
their families and friends,
or people who just happend to be in the wrong place at wrong time.
- Besides the criminal activity that enriches and protects the organization, missions are "requested"
by at least one foreign structure,
mostly, the Masonic Logia of Miami.
- The Royuela family has been calling out the criminal organization, suffered retaliations, a family
member , Javier Royuela Samit was killed,
Alberto spent about 18 monts in prison, and Santiago spent ten years.
- Since 2019, Santiago has been publishing the information, the writen notes and the lawsuits filed,
however,
no judge has been brave enough to conduct trials, the lawsuits have been archived.
- The only brave judge that has been helping the cause has suffered a forced exile from his position,
the judge Fernando Presencia.
- The royuela family has been defying authorities, but never been prosecuted for their claims.
- If Santiago and Alberto are lying, if the proofs are fake, how is it that none of the accused are
suiting them back?
What would happen if you were innocent and somebody would make fals claims againt you ?
would nt you suit them back and called them out?
- The information is spreading everywere, it is impossible to stop, that is why the damage control
policy has been to blame the Pegasus software filtrations.
- Some names that appear in the large ammount of notes, are the former president of Spain,
José-Luis Rodriguez Zapatero, the current defense minister, Margarita Robles,
the chief Prosecutor, Dolores Delgado, formers Prosecutor Carlos Jiménez Villarejo
and the chief of the high court of justice of Cataluña, José María Mena Álvarez...
- Now the story has taken an imprecedent turn, just a few days ago, Santiago has published
what is suppose to be,
the tombs of more that 40 people killed by the organization, and he is claming the the bodies
are buried in the warehouse
land, address Calle del Trueno nº 70, Leganés.
- Some people have alreaydy set camp in front of the warehouse, to make sure the bodies
are not moved out so no more covering should happen.
- May 19, 2022, Pedro Rossillo, youtube channel "El Arconte", went with his friend Carlos,
to the police station of Leganés, with the intention to present the proofs of
the Calle del Trueno nº 70, Leganés tombs, he is then beein tolled that there were no need for a new statement,
as they were aware of it already.
As he insisted to make his own statemant, a police officer told him :
If you are recoding with your phone, I would throw it out of the window,
and I ll throw you out of the window as well.
Pedro called out this threat to another 5 or 6 police officers who were just there,
but they said that their collegue talked about his phone, and did not t
Pedro wanted to make present a complaining against the police officer,
but then, the rest of the police officer started to put on their gloves, as they surounded both Pedro
and his friend Carlos.
At this point, knowing that the spanish police has the presuntion of truth,
they could have beating up and being accused of starting a fight wihtin the police station.
Funy enough, we have recently knew, that the police station received a suprise visit just a
day or so before that,
The current, home office minister: Fernando Grande-Marlaska.
https://nuestraespana.com/la-familia-...
https://www.youtube.com/c/SantiagoRoy...
56
views
5G MARTIN L PALL
MARTIN L. PALL in "FULL MEASURE"- SHARYL ATTKISSON (I love uuuu)
Phd Martin L Pall, described in the report as "one of the world prominent scientist on electromagnetic fields" talks about EMF, (electric and magnetic fields), 5G, biological effects, corruption in the health control institutions
Cant sleep?
Anxious
Depressed?
Tired all the time?
Headaches?
Can't concentrate?
Guess what. It is not sars-cov2.
Wifi, Cell towers, Smart Meters, Smartphones.+ Graphene Oxide injected in your shots, covid jabs, flue jab, any injectable substance since 2019...
Check on some of the works of Doctors Martin in https://www.researchgate.net/profile/Martin-Pall
102
views
Recopilatorio respiracionista volumen 1
Recopilatorio Volumen 1, música respiracionista de artistas libres:
01- A la mierda la nueva normalidad // artista desconocido desde Chile
02- La cancion de los borregos // Abraham Sevilla
03- El negacionista // Los Planetas
04- El Cobycoby // Alfredo Sosa - Carlos Rubio - Angie Rivera
05- No me toques los cojones // Alfredo Diaz - (www.alfredodiaz.es) - (Base melodica: Nirvana - Smells Like Teen Spirit)
06- Revolucion // Sonia B
07- Colapso // Anier & Dualy
08- Yaco Ómicron // (Cortito pero sustancioso sessions) Artista desconocido - Base melodica Watches Mr Czesky
09- Unión disidente Rap // Unión disidente
10- They live, we sleep, the alarms goin on bip bip..// Artista desconocido
11- Despertar // Artista desconocido - Base melodica (Marion Barfs composición Client Mansel)
12-Stick your new word order up your ass // we are the 99%
Portada gentileza del clip A la mierda la nueva normalidad // artista desconocido desde Chile
44
views
Respuesta del consejero de salud y familia de la comunidad andaluza preguntado informe Campra
- Oye, que me dicen que aquí hay algo tóxico !!!
- No lo pone en la etiqueta.
- Si ya sé que no lo pone en la etiqueta, alguien se ha molestado en revisarlo, vas a hacer algo? que mi padre le ha dado un chungo por tomar eso mismo!!!
- No lo pone en la etiqueta, ni la AMA lo dice, y está todo bien, ni es un estudio, ni es de la universidad de Almería, ni tiene Grafeno
y además, VERGUENZA TE DEBERÍA DAR, POR ALARMISTA!!!
"Llegará el día, en que todos tendremos que rendir cuentas, y yo tengo muuuuuy buena memoria..."
https://www.researchgate.net/publication/355684360_Deteccion_de_grafeno_en_vacunas_COVID19_por_espectroscopia_Micro-RAMAN
1
view
El que lleva la marca, le va de perlas
Este video es del 2013, Avicci murió en el 2018 con 28 años...
Dedicado a todos aquellos que no se quieren poner la marca, y al que me enseño el video hace un par de años, Fido Dido
Ánimo a todos, esto es una carrera de fondo, acordaros de elegir bien vuestras batallas !!
"El arte de la guerra" Sun Tzu
29
views
Dr. Campra´s technical report presentation// grafene oxyde in covid 19 vaccins.
Here, Doctor Pablo Campra Madrid, Almeria south of spain university and chemistry science professor is presenting his ending research on grafene presence in covid vaccines.
The research started late June 2021, you will find the first preliminary report, a special clarificatory report and the late report links, all published in researchgate.
November 05 2021: "DETECTION OF GRAPHENE IN COVID19 VACCINES"
https://www.researchgate.net/p....ublication/355979001
June 28 2021: "DETECCIÓN DE OXIDO DE GRAFENO �EN SUSPENSIÓN ACUOSA (COMIRNATYTM (RD1)��ESTUDIO OBSERVACIONAL EN MICROSCOPIA ÓPTICA Y ELECTRÓNICA�Informe provisional (I)"
https://www.researchgate.net/p....ublication/354059509
Biológicas.
July 23 2021: "ACLARACIÓN AL INFORME PRELIMINAR SOBRE LA PRESENCIA DE GRAFENO EN VACUNA mRNA COMIRNATY TM"
https://www.researchgate.net/p....ublication/353402485
Grafeno en vacunas, lípidos de grafeno en los componentes, ALC-0135 ∣ ALC-0159
Para mantenerse informado: laquintacolumna.net
LA QUINTA COLUMNA SOMOS TODOS
Karren Kingston, experta en documentación farmaceutica y cientifica, ex colaboradora de Pfizer y otras farmaceuticas nos enseña los coponentes de las vacunas hasta encontrar en la empresa SINOPEG china, los excipientes de grafeno utilizados en las vacunas.
Repasamos la documentación de la FDA Moderna Pfizer, las patentes china y la página SINOPEG para encontrar esta información.
Me he quedado corto en este directo y hay algunas páginas que me gustaría aclarar, pero lo tenéis todo para corroborar en la descripción, primero en la presentación de Karren y luego en los enlaces que voy a dejar aquí, dejo también algunos enlaces relacionados como el proyecto Eurolink de Elon Musk para el injerto de artefactos neuronales, demo en directo con cerdos, etc....
Presentación de Karren
"Evidence of Graphene Oxide in EUA
‘VACCINES’"
https://adelaidefreedomrally.com/wp-content/uploads/2021/08/2021.08.01-01.06-redvoicemedia-61069c71579fe.pdf
*********************************
"Moderna COVID-19 Vaccine EUA Fact Sheet for Recipients and Care"
https://www.fda.gov/media/144638/download
*********************************
"Public Assessment Report Authorisation for Temporary Supply COVID-19 mRNA Vaccine BNT162b2 (BNT162b2 RNA) concentrate for solution for injection Department of Health and Social Care (DHSC) Pfizer Limited & BioNTech Manufacturing GmbH"
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/997584/COVID-19_mRNA_Vaccine_BNT162b2__UKPAR___PFIZER_BIONTECH_ext_of_indication_11.6.2021.pdf
*********************************
"Sin estos escudos lipídicos, las vacunas Arn para el covid no serían posibles"
https://cen.acs.org/pharmaceuticals/drug-delivery/Without-lipid-shells-mRNA-vaccines/99/i8
*********************************
"Un mono jugando a un videojuego con la mente: proyecto Neuralink"
https://www.bbc.com/news/technology-56688812
*********************************
"¡REVELACIÓN COMPLETA! El chip Neuralink de Elon Musk probado en vivo en cerebros de cerdo"
https://www.youtube.com/watch?v=NqbQuZOFvOQ&t=80s
*********************************
"Elon Musk revela implate cerebral (es como tener un artefacto de monitorización deportiva en el cráneo)"
https://abcnews.go.com/Health/elon-musk-unveils-brain-chip-implant-fitbit-skull/story?id=72703840
*********************************
En el documento de Pfizer:
"Comirnaty, INN-COVID-19 mRNA Vaccine (nucleoside-modified)"
https://www.ema.europa.eu/en/documents/assessment-report/comirnaty-epar-public-assessment-report_en.pdf
.(..Other ingredients are: ALC-0315 (4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-
hexyldecanoate), ALC-0159 (2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide), 1,2-
Assessment report
EMA/707383/2020 Page 15/140
Distearoyl-sn-glycero-3-phosphocholine (DSPC), cholesterol, potassium chloride, potassium dihydrogen
phosphate, sodium chloride, disodium phosphate dihydrate, sucrose and water for injections.)
*********************************
https://www.fda.gov/media/144416/download
Emergency Use Authorization (EUA) for an Unapproved Product Review Memorandum
Pag 11
*********************************
https://www.sinopeg.com/polyethylene-glycol-peg-2000-dimyristoyl-glycerol-dmg-mpeg2000-dmg-cas-160743-62-4_p479.html
Compuesto:
"Polyethylene glycol [PEG] 2000 dimyristoyl glycerol [DMG] [mPEG2000-DMG] Cas:160743-62-4
mPEG2000-DMG"
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"Núcleo-escudo de estructura de polietilenglicol funcionalizado grafeno para dieléctricos poliméricos de almacenamiento de energía: Prestaciones mecánicas y dieléctricas combinadas"
https://www.sinopeg.com/core-shell-structured-polyethylene-glycol-functionalized-graphene-for-energy-storage-polymer-dielectrics-combined-mechanical-and-dielectric-performances_n28
*********************************
"1. WO2020160397 - METHODS OF PREPARING LIPID NANOPARTICLES"
https://patentscope2.wipo.int/search/en/detail.jsf?docId=WO2020160397&tab=PCTDESCRIPTION
*********************************
"Nano coronavirus recombinant vaccine taking graphene oxide as carrier"
https://patents.google.com/patent/CN112220919A/en
(La invención pertenece al campo de los nano materiales y la biomedicina, y se refiere a una vacuna, en particular al
desarrollo de una nanovacuna nuclear recombinante contra el coronavirus 2019-nCoV.
La invención también incluye también el metodo de preparación de la vacuna y la aplicación de la vacuna en experimentos realizados con animales. La nueva vacuna
contra el coronavirus contiene óxido de grafeno carnosina, CpG y el nuevo corona virus RBD;
carnosina, el CpG y el RBD del neocoronavirus uniendose a la columna vertebral del óxido de grafeno; la
secuencia de codificación de CpG se muestra como SEQ ID NO 1; la nueva RBD del coronavirus se refiere a una nueva región de unión al receptor de la proteína del
coronavirus que puede generar un anticuerpo específico de alta carga dirigido al RBD en el cuerpo de un ratón, y proporciona una gran ayuda en
la prevención y el tratamiento del nuevo coronavirus).
Aparece como tiutular de la patente: Shanghai National Engineering Research Center for Nanotechnology Co Ltd
*********************************
"National Engineering Research Center for Nanotechnology"
https://en.sjtu.edu.cn/research/centers-labs/national-engineering-research-center-for-nanotechnology
Nota del que escribe:
En este enlace, se ncluye la fotografia de uno del Director Médico, Tal Zachs (https://www.linkedin.com/in/talzaks/) de visita a este centro de investigación
que presenta la patente para el oxido de grafeno como excipiente en las vacunas.
*********************************
Transcripción y resumen:
- La quinta columna y Doctora Jane Ruby, resumen del programa anterior
- Karen: "es dificil ligar toda la información que revelo ya que conozco el sistema y tengo las habilidades para poder hacer la lectura técnica legal y de propiedad intelectual de estos componentes"
-Stew Peters: "¿ hay óxido de grafeno en las inyecciones ? “100% yes”, significa absolutamente, min 03:16
- Karen: "todas las vacunas Arn contienen unas nanopartículas lipídicas que se conocen como “PEGylated lipinal nanoparticles”
- Karen: "..en la patente de Moderna, 193 páginas más adjuntos, no aparece la mención de óxido de grafeno, pero en la patente china si
es un Traded secret: componente secreto...
..dicho por Bill Gates, que las vacunas tendrían un componente secreto
-Stew Peters: "¿ por qué se mencionarían todos los componentes menos el óxido de grafeno ?
- Karen: " , diría que el motivo principal es porque es venenoso para los seres humanos
la otra razón es porque es el componente principal del hidrogel, el líquido utilizado como modelo para la inteligencia artificial para ciertas investigaciones.."
min 4:47
de Bill Gates y Elon Musk para la creación de una interfaz cerebro máquina (internet)."
-Stew Peters: "¿ me estás diciendo que hay teoría legitima (posible) de inyecciones control mental 5G ?
- Karen: "No es posible en este estado de la investigación, han acelerado las cosas, están viendo como reaccionan la gente (cuanta cantidad pueden meter antes de que mueran) min: 05:35
-Stew Peters: "¿por lo que estos son dosis de estudio, todas las personas que están muriendo, las reacciones, esclerosis múltiple, síndrome de Guillán Barré, convulsiones, magnetismo.. ?
- Karen: "-” Acuérdate que nos han dicho que hay que recibir una dosis cada 6 meses, así que vamos a tener un refuerzo de Grafeno cada 6 meses para ver cuanta cantidad somos capaces de absorber..”
los países están inyectados y una vez que hayan desarrollado esta tecnología, creo que hay un segundo plan, no me gusta dar opiniones, prefiero quedarme en los hechos…”
- Karen: "Si echamos un ojo los artículos de la ingeniería y química, existen estas revistas que llamamos ratas (no verificado por pares), en él la gente presume de su importancia en el mercado...”
en este artículo, se habla de los 4 lípidos
https://cen.acs.org/pharmaceuticals/drug-delivery/Without-lipid-shells-mRNA-vaccines/99/i8
“Without these lipid shells, there would be no mRNA vaccines for COVID-19”
Cholesterol: Nuestro cuerpo lo segrega y pasa a través la sangre.
Phospholipid: se adhiere a la membrana celular, así que permite la permeabilidad para atravesar la membrana celular
un lípido ionizable, lo que confiere una carga positiva al lípido para ayudar el Arn penetrar la célula
y luego están los PEGylated lipides."
Motivos para el uso de estos lípidos:
- Karen:
" El arn es inestable
Da igual que sea sintético (creado en laboratorio) o de origen animal (zoonic), o humando, muere con facilidad.
a partir de 80º Fahrenheit, 26º Centígrados, muere
la luz del sol lo mata
si respiras encima muere
Raramente llega a pasar el umbral de la zona NESAL FARENS AREA isotérmica de un individuo sano
La saliva lo mata
Necesita esta biosfera que se ha creado, para eso están estos 4 lípidos y luego añaden el óxido de grafeno…
El óxido de grafeno es 4000 veces más resistente que el Titanio
Soporta temperaturas de 17000 º Farenheit = 9426.667℃
nota del que escribe: (Aquí es donde no coincidimos, dice que han tomado este “virus” inestable y lo han hecho indestructible. El Arn que se introduce ya sabemos que no proviene del virus ya que no hay virus aislado cultivado en laboratorio para hacer esta operación)
Si nos fijamos, el PEG de PEGylated lipids, fabricadas por una compañía llamada SYNOPEG
He encontrado esta información mirando la documentación de la Pfizer EUA (uso de autorización de emergencia), están citadas ahí, en la de Moderna tb
Moderna ha llamado en los documentos de ficha de seguridad, (MSDS) con un número CAS, los lípidos se llaman SM-102 para Moderna
En la documentación Británica de Pfizer, los lípidos son llamados ALC-0315 y ALC-0159
Cuando he puesto esos números MSDS en Google, es cuando caí sobre la empresa SINOPEG
En la patente de moderna, se listan todas las polietileno, 200, 2000, y los encontrarás en la página de SINOPEG como excipientes para la covid-19
Está ahí, fabricado en China
Otras vacunas no fabricadas en EEUU, tb tienen estos compuestos que se encuentran por los números de MSDS
El grafeno puede ser un conductor de electricidad
si tiene una carga positiva, “aniquila” todo aquello con lo que va a entrar en contacto
Ahora mismo no están cargados, están neutralizados,
¿ Cómo puede una carga positiva entrar en las células ?
OJO AQUÍIIIIIIII
¡¡¡¡¡¡LA OTRA LIPIDE, LA IONIZABLE QUE CONFIERE LA CARGA POSITICA PARA LA PENETRACIÓN CELULAR!!!!!!
La otra Lipide, la ionizable que confiere la carga positiva para la penetración celular,
pero si hay un campo electomagético que active estas cargas positivas, muertes y daños potenciales,
DEPENDIENDO DE LA CANTIDAD Y DEL EMPLACAMIENTO DEL GRAFENO EN EL CUERPO EN ESE MOMEMENT!!!!!!!
Para mantenerse informado: laquintacolumna.net
LA QUINTA COLUMNA SOMOS TODOS
Sobre los lípidos de grafeno para vacunas: Primera parte
Primera parte del desglose de documentos y explicación de la información de Karen Kingston en el Peter Stew Show, presencia de lípidos de grafeno como excipiente del Arn en las vacunas, documentación disponible en la presentación de Karren y en esta descripción:
https://odysee.com/@Barbotin:6/StewPeters-Karen-Kingston-graphene:d?
Presentation de Karen:
https://adelaidefreedomrally.com/wp-content/uploads/2021/08/2021.08.01-01.06-redvoicemedia-61069c71579fe.pdf
Enlaces de interés:
https://www.sinopeg.com/core-shell-structured-polyethylene-glycol-functionalized-graphene-for-energy-storage-polymer-dielectrics-combined-
mechanical-and-dielectric-performances_n28
"Core-shell structured polyethylene glycol functionalized graphene for energy-storage polymer dielectrics: Combined mechanical and dielectric performances
SEPTEMBER 1,2020.
Graphene, as the thinnest, strongest and stiffest material and arranged in a honeycomb pattern structure with sp2-hybridized carbon, finds more
potential applications in modern industry than other carbonaceous allotropes; in pristine form, it is also an excellent heat and electric conductor .
However, the major obstacle in utilizing graphene, particularly for electronic applications, is its insolubility in the fully reduced state due to the
strong affinity between the graphene sheets."
https://www.sinopeg.com/2-polyethylene-glycol-2000-n-n-ditetradecylacetamide-alc-0159-cas-1849616-42-7_p477.html
2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide[ALC-0159] CAS: 1849616-42-7
Shanghai National Engineering Research Center for Nanotechnology:
https://en.sjtu.edu.cn/research/centers-labs/national-engineering-research-center-for-nanotechnology
Patente:
https://patents.google.com/patent/CN112220919A/en
"Nano coronavirus recombinant vaccine taking graphene oxide as carrier"
ALC-0159 Wikipedia:
https://en.wikipedia.org/wiki/ALC-0159
Articulo:
"Without these lipid shells, there would be no mRNA vaccines for COVID-19"
https://cen.acs.org/pharmaceuticals/drug-delivery/Without-lipid-shells-mRNA-vaccines/99/i8
Componentes de la vacuna Pfizer:
https://www.fda.gov/media/144412/download
"Each dose of the Pfizer-BioNTech COVID-19 Vaccine also includes the following ingredients:
lipids (0.43 mg (4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate), 0.05 mg
2[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide, 0.09 mg 1,2-distearoyl-sn-glycero-3-
phosphocholine, and 0.2 mg cholesterol), 0.01 mg potassium chloride, 0.01 mg monobasic
potassium phosphate, 0.36 mg sodium chloride, 0.07 mg dibasic sodium phosphate dihydrate,
and 6 mg sucrose. The diluent (0.9% Sodium Chloride Injection) contributes an additional 2.16
mg sodium chloride per dose."
Public Assessment Report
Authorisation for Temporary Supply
COVID-19 mRNA Vaccine BNT162b2
(BNT162b2 RNA)
concentrate for solution for injection
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/997584/COVID-19_mRNA_Vaccine_BNT162b2UKPAR_PFIZERBIONTECH
ext_of_indication_11.6.2021.pdf
"Excipients
The excipients sucrose, sodium chloride, potassium chloride, dibasic sodium phosphate
dihydrate, monobasic potassium phosphate and water for injection are all of Ph. Eur. grades,
which are acceptable.
In addition to those excipients, the vaccine contains four lipids, of which two are used in
approved medicinal products (cholesterol and 1,2-distearoyl-sn-glycero-3-phosphocholine,
hereafter termed DSPC) and two are considered novel in that they have not been used in an
authorised medicinal product in the UK:
ALC-0315 ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate)) and
ALC-0159 (2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide).
The lipids are intended to encapsulate the mRNA in the form of a lipid nanoparticle to aid
cell entry and stability of the RNA/lipid nanoparticles.
ALC-0315 is the functional cationic lipid component of the drug product. When incorporated
in lipid nanoparticles, it helps regulate the endosomal release of the RNA. During drug
product manufacturing, introduction of an aqueous RNA solution to an ethanolic lipid
mixture containing ALC-0315 at a specific pH leads to an electrostatic interaction between
the negatively charged RNA backbone and the positively charged cationic lipid. This
electrostatic interaction leads to encapsulation of RNA drug substance resulting with particle
formation. Once the lipid nanoparticle is taken up by the cell, the low pH of the endosome
renders the LNP fusogenic and allows the release of the RNA into the cytosol.
The primary function of the PEGylated lipid ALC-0159 is to form a protective hydrophilic
layer that sterically stabilises the LNP which contributes to storage stability and reduces nonspecific binding to proteins. As higher PEG content can reduce
cellular up"
Para mantenerse informado y participar en destapar la verdad, entra en la quinta columna
LA QUINTA COLUMNA SOMOS TODOS
laquintacolumna.net
le graphéne// الحلقة اخامسة// بالعربي
Video Karen Kington chez Stew Peters show:
https://odysee.com/@Barbotin:6/StewPeters-Karen-Kingston-graphene:d?
Présentation de Karen:
https://adelaidefreedomrally.com/wp-content/uploads/2021/08/2021.08.01-01.06-redvoicemedia-61069c71579fe.pdf
Page importante:
https://www.sinopeg.com/core-shell-structured-polyethylene-glycol-functionalized-graphene-for-energy-storage-polymer-dielectrics-combined-
mechanical-and-dielectric-performances_n28
"Core-shell structured polyethylene glycol functionalized graphene for energy-storage polymer dielectrics: Combined mechanical and dielectric performances
SEPTEMBER 1,2020.
Graphene, as the thinnest, strongest and stiffest material and arranged in a honeycomb pattern structure with sp2-hybridized carbon, finds more
potential applications in modern industry than other carbonaceous allotropes; in pristine form, it is also an excellent heat and electric conductor .
However, the major obstacle in utilizing graphene, particularly for electronic applications, is its insolubility in the fully reduced state due to the
strong affinity between the graphene sheets."
https://www.sinopeg.com/2-polyethylene-glycol-2000-n-n-ditetradecylacetamide-alc-0159-cas-1849616-42-7_p477.html
2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide[ALC-0159] CAS: 1849616-42-7
Shanghai National Engineering Research Center for Nanotechnology:
https://en.sjtu.edu.cn/research/centers-labs/national-engineering-research-center-for-nanotechnology
Brevet:
https://patents.google.com/patent/CN112220919A/en
"Nano coronavirus recombinant vaccine taking graphene oxide as carrier"
ALC-0159 Wikipedia:
https://en.wikipedia.org/wiki/ALC-0159
Article:
"Without these lipid shells, there would be no mRNA vaccines for COVID-19"
https://cen.acs.org/pharmaceuticals/drug-delivery/Without-lipid-shells-mRNA-vaccines/99/i8
Composant du vaccin Pfizer:
https://www.fda.gov/media/144412/download
"Each dose of the Pfizer-BioNTech COVID-19 Vaccine also includes the following ingredients:
lipids (0.43 mg (4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate), 0.05 mg
2[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide, 0.09 mg 1,2-distearoyl-sn-glycero-3-
phosphocholine, and 0.2 mg cholesterol), 0.01 mg potassium chloride, 0.01 mg monobasic
potassium phosphate, 0.36 mg sodium chloride, 0.07 mg dibasic sodium phosphate dihydrate,
and 6 mg sucrose. The diluent (0.9% Sodium Chloride Injection) contributes an additional 2.16
mg sodium chloride per dose."
Public Assessment Report
Authorisation for Temporary Supply
COVID-19 mRNA Vaccine BNT162b2
(BNT162b2 RNA)
concentrate for solution for injection
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/997584/COVID-19_mRNA_Vaccine_BNT162b2UKPAR_PFIZERBIONTECH
ext_of_indication_11.6.2021.pdf
"Excipients
The excipients sucrose, sodium chloride, potassium chloride, dibasic sodium phosphate
dihydrate, monobasic potassium phosphate and water for injection are all of Ph. Eur. grades,
which are acceptable.
In addition to those excipients, the vaccine contains four lipids, of which two are used in
approved medicinal products (cholesterol and 1,2-distearoyl-sn-glycero-3-phosphocholine,
hereafter termed DSPC) and two are considered novel in that they have not been used in an
authorised medicinal product in the UK:
ALC-0315 ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate)) and
ALC-0159 (2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide).
The lipids are intended to encapsulate the mRNA in the form of a lipid nanoparticle to aid
cell entry and stability of the RNA/lipid nanoparticles.
ALC-0315 is the functional cationic lipid component of the drug product. When incorporated
in lipid nanoparticles, it helps regulate the endosomal release of the RNA. During drug
product manufacturing, introduction of an aqueous RNA solution to an ethanolic lipid
mixture containing ALC-0315 at a specific pH leads to an electrostatic interaction between
the negatively charged RNA backbone and the positively charged cationic lipid. This
electrostatic interaction leads to encapsulation of RNA drug substance resulting with particle
formation. Once the lipid nanoparticle is taken up by the cell, the low pH of the endosome
renders the LNP fusogenic and allows the release of the RNA into the cytosol.
The primary function of the PEGylated lipid ALC-0159 is to form a protective hydrophilic
layer that sterically stabilises the LNP which contributes to storage stability and reduces nonspecific binding to proteins. As higher PEG content can reduce
cellular up"
le graphéne// الحلقة الرابعة// بالعربي
Video Karen Kington chez Stew Peters show:
https://odysee.com/@Barbotin:6/StewPeters-Karen-Kingston-graphene:d?
Présentation de Karen:
https://adelaidefreedomrally.com/wp-content/uploads/2021/08/2021.08.01-01.06-redvoicemedia-61069c71579fe.pdf
Page importante:
https://www.sinopeg.com/core-shell-structured-polyethylene-glycol-functionalized-graphene-for-energy-storage-polymer-dielectrics-combined-
mechanical-and-dielectric-performances_n28
"Core-shell structured polyethylene glycol functionalized graphene for energy-storage polymer dielectrics: Combined mechanical and dielectric performances
SEPTEMBER 1,2020.
Graphene, as the thinnest, strongest and stiffest material and arranged in a honeycomb pattern structure with sp2-hybridized carbon, finds more
potential applications in modern industry than other carbonaceous allotropes; in pristine form, it is also an excellent heat and electric conductor .
However, the major obstacle in utilizing graphene, particularly for electronic applications, is its insolubility in the fully reduced state due to the
strong affinity between the graphene sheets."
https://www.sinopeg.com/2-polyethylene-glycol-2000-n-n-ditetradecylacetamide-alc-0159-cas-1849616-42-7_p477.html
2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide[ALC-0159] CAS: 1849616-42-7
Shanghai National Engineering Research Center for Nanotechnology:
https://en.sjtu.edu.cn/research/centers-labs/national-engineering-research-center-for-nanotechnology
Brevet:
https://patents.google.com/patent/CN112220919A/en
"Nano coronavirus recombinant vaccine taking graphene oxide as carrier"
ALC-0159 Wikipedia:
https://en.wikipedia.org/wiki/ALC-0159
Article:
"Without these lipid shells, there would be no mRNA vaccines for COVID-19"
https://cen.acs.org/pharmaceuticals/drug-delivery/Without-lipid-shells-mRNA-vaccines/99/i8
Composant du vaccin Pfizer:
https://www.fda.gov/media/144412/download
"Each dose of the Pfizer-BioNTech COVID-19 Vaccine also includes the following ingredients:
lipids (0.43 mg (4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate), 0.05 mg
2[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide, 0.09 mg 1,2-distearoyl-sn-glycero-3-
phosphocholine, and 0.2 mg cholesterol), 0.01 mg potassium chloride, 0.01 mg monobasic
potassium phosphate, 0.36 mg sodium chloride, 0.07 mg dibasic sodium phosphate dihydrate,
and 6 mg sucrose. The diluent (0.9% Sodium Chloride Injection) contributes an additional 2.16
mg sodium chloride per dose."
Public Assessment Report
Authorisation for Temporary Supply
COVID-19 mRNA Vaccine BNT162b2
(BNT162b2 RNA)
concentrate for solution for injection
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/997584/COVID-19_mRNA_Vaccine_BNT162b2UKPAR_PFIZERBIONTECH
ext_of_indication_11.6.2021.pdf
"Excipients
The excipients sucrose, sodium chloride, potassium chloride, dibasic sodium phosphate
dihydrate, monobasic potassium phosphate and water for injection are all of Ph. Eur. grades,
which are acceptable.
In addition to those excipients, the vaccine contains four lipids, of which two are used in
approved medicinal products (cholesterol and 1,2-distearoyl-sn-glycero-3-phosphocholine,
hereafter termed DSPC) and two are considered novel in that they have not been used in an
authorised medicinal product in the UK:
ALC-0315 ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate)) and
ALC-0159 (2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide).
The lipids are intended to encapsulate the mRNA in the form of a lipid nanoparticle to aid
cell entry and stability of the RNA/lipid nanoparticles.
ALC-0315 is the functional cationic lipid component of the drug product. When incorporated
in lipid nanoparticles, it helps regulate the endosomal release of the RNA. During drug
product manufacturing, introduction of an aqueous RNA solution to an ethanolic lipid
mixture containing ALC-0315 at a specific pH leads to an electrostatic interaction between
the negatively charged RNA backbone and the positively charged cationic lipid. This
electrostatic interaction leads to encapsulation of RNA drug substance resulting with particle
formation. Once the lipid nanoparticle is taken up by the cell, the low pH of the endosome
renders the LNP fusogenic and allows the release of the RNA into the cytosol.
The primary function of the PEGylated lipid ALC-0159 is to form a protective hydrophilic
layer that sterically stabilises the LNP which contributes to storage stability and reduces nonspecific binding to proteins. As higher PEG content can reduce
cellular up"
le graphéne- الحلقة الثالثه- بالعربي
Video Karen Kington chez Stew Peters show:
https://odysee.com/@Barbotin:6/StewPeters-Karen-Kingston-graphene:d?
Présentation de Karen:
https://adelaidefreedomrally.com/wp-content/uploads/2021/08/2021.08.01-01.06-redvoicemedia-61069c71579fe.pdf
Page importante:
https://www.sinopeg.com/core-shell-structured-polyethylene-glycol-functionalized-graphene-for-energy-storage-polymer-dielectrics-combined-
mechanical-and-dielectric-performances_n28
"Core-shell structured polyethylene glycol functionalized graphene for energy-storage polymer dielectrics: Combined mechanical and dielectric performances
SEPTEMBER 1,2020.
Graphene, as the thinnest, strongest and stiffest material and arranged in a honeycomb pattern structure with sp2-hybridized carbon, finds more
potential applications in modern industry than other carbonaceous allotropes; in pristine form, it is also an excellent heat and electric conductor .
However, the major obstacle in utilizing graphene, particularly for electronic applications, is its insolubility in the fully reduced state due to the
strong affinity between the graphene sheets."
https://www.sinopeg.com/2-polyethylene-glycol-2000-n-n-ditetradecylacetamide-alc-0159-cas-1849616-42-7_p477.html
2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide[ALC-0159] CAS: 1849616-42-7
Shanghai National Engineering Research Center for Nanotechnology:
https://en.sjtu.edu.cn/research/centers-labs/national-engineering-research-center-for-nanotechnology
Brevet:
https://patents.google.com/patent/CN112220919A/en
"Nano coronavirus recombinant vaccine taking graphene oxide as carrier"
ALC-0159 Wikipedia:
https://en.wikipedia.org/wiki/ALC-0159
Article:
"Without these lipid shells, there would be no mRNA vaccines for COVID-19"
https://cen.acs.org/pharmaceuticals/drug-delivery/Without-lipid-shells-mRNA-vaccines/99/i8
Composant du vaccin Pfizer:
https://www.fda.gov/media/144412/download
"Each dose of the Pfizer-BioNTech COVID-19 Vaccine also includes the following ingredients:
lipids (0.43 mg (4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate), 0.05 mg
2[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide, 0.09 mg 1,2-distearoyl-sn-glycero-3-
phosphocholine, and 0.2 mg cholesterol), 0.01 mg potassium chloride, 0.01 mg monobasic
potassium phosphate, 0.36 mg sodium chloride, 0.07 mg dibasic sodium phosphate dihydrate,
and 6 mg sucrose. The diluent (0.9% Sodium Chloride Injection) contributes an additional 2.16
mg sodium chloride per dose."
Public Assessment Report
Authorisation for Temporary Supply
COVID-19 mRNA Vaccine BNT162b2
(BNT162b2 RNA)
concentrate for solution for injection
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/997584/COVID-19_mRNA_Vaccine_BNT162b2UKPAR_PFIZERBIONTECH
ext_of_indication_11.6.2021.pdf
"Excipients
The excipients sucrose, sodium chloride, potassium chloride, dibasic sodium phosphate
dihydrate, monobasic potassium phosphate and water for injection are all of Ph. Eur. grades,
which are acceptable.
In addition to those excipients, the vaccine contains four lipids, of which two are used in
approved medicinal products (cholesterol and 1,2-distearoyl-sn-glycero-3-phosphocholine,
hereafter termed DSPC) and two are considered novel in that they have not been used in an
authorised medicinal product in the UK:
ALC-0315 ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate)) and
ALC-0159 (2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide).
The lipids are intended to encapsulate the mRNA in the form of a lipid nanoparticle to aid
cell entry and stability of the RNA/lipid nanoparticles.
ALC-0315 is the functional cationic lipid component of the drug product. When incorporated
in lipid nanoparticles, it helps regulate the endosomal release of the RNA. During drug
product manufacturing, introduction of an aqueous RNA solution to an ethanolic lipid
mixture containing ALC-0315 at a specific pH leads to an electrostatic interaction between
the negatively charged RNA backbone and the positively charged cationic lipid. This
electrostatic interaction leads to encapsulation of RNA drug substance resulting with particle
formation. Once the lipid nanoparticle is taken up by the cell, the low pH of the endosome
renders the LNP fusogenic and allows the release of the RNA into the cytosol.
The primary function of the PEGylated lipid ALC-0159 is to form a protective hydrophilic
layer that sterically stabilises the LNP which contributes to storage stability and reduces nonspecific binding to proteins. As higher PEG content can reduce
cellular up"
272
views
le graphéne- الحلقة التانية- بالعربي
Kifach nchoufou wash tahalil bsignature digital madbout:
https://verificarfirma.ual.es/verifirma/pages/verification-code.htm;jsessionid=sFYo-ktfbj9B9AdyLtfF2M2bdghxl_BGL3LgwmUr.pfirma
l code dyal le report dyal Doctor Campra Madrid:
https://www.docdroid.net/rNgtxyh/microscopia-de-vial-corminaty-dr-campra-firma-e-1-fusionado-pdf
Video Karen Kington chez Stew Peters show:
https://odysee.com/@Barbotin:6/StewPeters-Karen-Kingston-graphene:d?
Présentation de Karen:
https://adelaidefreedomrally.com/wp-content/uploads/2021/08/2021.08.01-01.06-redvoicemedia-61069c71579fe.pdf
Page importante:
https://www.sinopeg.com/core-shell-structured-polyethylene-glycol-functionalized-graphene-for-energy-storage-polymer-dielectrics-combined-
mechanical-and-dielectric-performances_n28
"Core-shell structured polyethylene glycol functionalized graphene for energy-storage polymer dielectrics: Combined mechanical and dielectric performances
SEPTEMBER 1,2020.
Graphene, as the thinnest, strongest and stiffest material and arranged in a honeycomb pattern structure with sp2-hybridized carbon, finds more
potential applications in modern industry than other carbonaceous allotropes; in pristine form, it is also an excellent heat and electric conductor .
However, the major obstacle in utilizing graphene, particularly for electronic applications, is its insolubility in the fully reduced state due to the
strong affinity between the graphene sheets."
https://www.sinopeg.com/2-polyethylene-glycol-2000-n-n-ditetradecylacetamide-alc-0159-cas-1849616-42-7_p477.html
2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide[ALC-0159] CAS: 1849616-42-7
Shanghai National Engineering Research Center for Nanotechnology:
https://en.sjtu.edu.cn/research/centers-labs/national-engineering-research-center-for-nanotechnology
Brevet:
https://patents.google.com/patent/CN112220919A/en
"Nano coronavirus recombinant vaccine taking graphene oxide as carrier"
ALC-0159 Wikipedia:
https://en.wikipedia.org/wiki/ALC-0159
Article:
"Without these lipid shells, there would be no mRNA vaccines for COVID-19"
https://cen.acs.org/pharmaceuticals/drug-delivery/Without-lipid-shells-mRNA-vaccines/99/i8
Composant du vaccin Pfizer:
https://www.fda.gov/media/144412/download
"Each dose of the Pfizer-BioNTech COVID-19 Vaccine also includes the following ingredients:
lipids (0.43 mg (4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate), 0.05 mg
2[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide, 0.09 mg 1,2-distearoyl-sn-glycero-3-
phosphocholine, and 0.2 mg cholesterol), 0.01 mg potassium chloride, 0.01 mg monobasic
potassium phosphate, 0.36 mg sodium chloride, 0.07 mg dibasic sodium phosphate dihydrate,
and 6 mg sucrose. The diluent (0.9% Sodium Chloride Injection) contributes an additional 2.16
mg sodium chloride per dose."
Public Assessment Report
Authorisation for Temporary Supply
COVID-19 mRNA Vaccine BNT162b2
(BNT162b2 RNA)
concentrate for solution for injection
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/997584/COVID-19_mRNA_Vaccine_BNT162b2UKPAR_PFIZERBIONTECH
ext_of_indication_11.6.2021.pdf
"Excipients
The excipients sucrose, sodium chloride, potassium chloride, dibasic sodium phosphate
dihydrate, monobasic potassium phosphate and water for injection are all of Ph. Eur. grades,
which are acceptable.
In addition to those excipients, the vaccine contains four lipids, of which two are used in
approved medicinal products (cholesterol and 1,2-distearoyl-sn-glycero-3-phosphocholine,
hereafter termed DSPC) and two are considered novel in that they have not been used in an
authorised medicinal product in the UK:
ALC-0315 ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate)) and
ALC-0159 (2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide).
The lipids are intended to encapsulate the mRNA in the form of a lipid nanoparticle to aid
cell entry and stability of the RNA/lipid nanoparticles.
ALC-0315 is the functional cationic lipid component of the drug product. When incorporated
in lipid nanoparticles, it helps regulate the endosomal release of the RNA. During drug
product manufacturing, introduction of an aqueous RNA solution to an ethanolic lipid
mixture containing ALC-0315 at a specific pH leads to an electrostatic interaction between
the negatively charged RNA backbone and the positively charged cationic lipid. This
electrostatic interaction leads to encapsulation of RNA drug substance resulting with particle
formation. Once the lipid nanoparticle is taken up by the cell, the low pH of the endosome
renders the LNP fusogenic and allows the release of the RNA into the cytosol.
The primary function of the PEGylated lipid ALC-0159 is to form a protective hydrophilic
layer that sterically stabilises the LNP which contributes to storage stability and reduces nonspecific binding to proteins. As higher PEG content can reduce
cellular up"
le graphéne// الحلقة الؤلة // بالعربي
Que contiennent les vaccins covid ?
الحلقة الؤلة
https://www.docdroid.net/rNgtxyh/microscopia-de-vial-corminaty-dr-campra-firma-e-1-fusionado-pdf#page=3
https://www.laquintacolumna.net/