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cas: 1222814-77-8 2C-EF CBNumber: CB28375360 Chemical Name: Benzeneethanamine, 4-(2-fluoroethyl)-2,5-dimethoxy- Molecular Formula: C12H18FNO2 Formula Weight: 227.28 CAS No.: 1222814-77-8

CBNumber: CB82715986 cas: 134984-63-7 2-Azabicyclo[2.2.1]hept-5-ene-3-carboxylic acid, 2-[(1R)-1-phenylethyl]-, ethyl ester, (1S,3S,4R)- Molecular Formula: C17H21NO2 Formula Weight: 271.35 CAS No.: 134984-63-7

cas: 2660255-85-4 Isoquinoline, 8-bromo-3-chloro-5-(1-methylethyl)- CBNumber: CB59798440 Chemical Name: Isoquinoline, 8-bromo-3-chloro-5-(1-methylethyl)- Molecular Formula: C12H11BrClN Formula Weight: 284.58 CAS No.: 2660255-85-4

cas: 10154-71-9 3-(Phenylsulfonyl)propionic acid CBNumber: CB2730763 Chemical Name: 3-(PHENYLSULFONYL)PROPIONIC ACID Molecular Formula: C9H10O4S Formula Weight: 214.24 CAS No.: 10154-71-9

cas: 887471-39-8 6-Chloro-3-hydroxy-2-nitropyridine CBNumber: CB61471304 Chemical Name: 6-Chloro-3-hydroxy-2-nitropyridine Molecular Formula: C5H3ClN2O3 Formula Weight: 174.54 CAS No.: 887471-39-8

cas: 10406-06-1 5-Bromoindole-3-carboxylic Acid CBNumber: CB7142938 Chemical Name: 5-BROMO-1H-INDOLE-3-CARBOXYLIC ACID Molecular Formula: C9H6BrNO2 Formula Weight: 240.05 CAS No.: 10406-06-1

cas: 18464-52-3 new Rolicyclidine ( PCPy )

cas: 2201-39-0 Rolicyclidine ( PCPy ) CBNumber: CB81179680 Chemical Name: Rolicyclidine Molecular Formula: C16H23N Formula Weight: 229.36 CAS No.: 2201-39-0

cas: 210821-63-9 Org12962 HCl hydrochloride Org-12962 CBNumber: CB02473321 Chemical Name: Org 12962 HCl Molecular Formula: C10H11ClF3N3.ClH Formula Weight: 302.126 CAS No.: 210821-63-9 ORG-12962 is a pyridinylpiperazine drug developed by Organon, which acts as a potent and selective agonist for the 5-HT2 receptor family, with highest affinity at 5-HT2C and lowest at 5-HT2B subtypes. It was developed as a potential anti-anxiety drug, but was discontinued from human trials after tests in a public speaking challenge showed that its anti-anxiety effects were accompanied by side effects such as dizziness and a "spacey" feeling, which were attributed to poor selectivity in vivo over the hallucinogenic 5-HT2A receptor.

cas: 189691-06-3 bremelanotide PT141 PT-141 PT-141, a synthetic peptide analogue of alpha-MSH, is an agonist at melanocortin receptors including the MC3R and MC4R, which are expressed primarily in the central nervous system. Administration of PT-141 to rats and nonhuman primates results in penile erections. PT-141, also known as bremelanotide, is an innovative new peptide hormone treatment that works for both men and women to improve sexual function. PT-141 is an effective and efficient treatment for both erectile dysfunction and increased libido in men and improves female sexual arousal disorder in women. PT 141 peptide gives you the desire and motivation along with the ability to increase blood flow to the penis or vagina and clitoris, returning the intimacy and passion to your relationship. PT 141 addresses those issues to help resolve sexual difficulties. PT-141 works directly through the nervous system to increase arousal, desire, and satisfaction with sex. Treatments like Viagra and Cialis work through the vascular system and only give you the ability to achieve an erection. However, PT-141 gives you the desire and motivation along with the ability to achieve an erection, returning the intimacy and passion to your relationship. PT-141 is empowering our female patients by rejuvenating their sex drive! One third of the population experienced sexual dysfunction, according to a 2015 survey. In the older pool of premenopausal women, approximately six million suffer from hypoactive sexual desire disorder (HSDD). If you happen to be someone in one of these pools, you are clearly not alone. Our peptide PT-141 can possible be the answer you are looking for. How exciting is this? PT-141 is a medication that can help boost your sexual desire, bodily engagement and performance like nothing else on the market. AIM has the purest pharmacy form of the peptide made for the ultimate results. BREMELANOTIDE PT 141 PEPTIDE Most of us are no strangers to the decline in sex drive that typically comes with age. But, it doesn’t have to be this way! Bremelanotide PT 141 provides a natural solution to this dilemma of decreased libido. At AgeRejuvenation, it’s our job to inform you on the variety of options available when it comes to taking health into your own hands. Keep reading to learn all about PT 141’s benefits and applications. WHAT IS BREMELANOTIDE PT 141? Bremelanotide PT 141 peptide is a chemical that binds to and activates a cellular receptor—in this case, the melanocortin receptors associated with skin pigmentation. This synthetic peptide, known as Bremelanotide, was originally developed from a hormone that induces skin tanning, Melanotan II. During initial tests, the discovery that Melanotan II caused the side effects of sexual arousal and erections was actually a pleasant surprise. These effects occurred in 9 out of 10 male volunteers in a study conducted at the University of Arizona by Dr. Hunter Wells. Discovery of PT 141 Revolutionized Sexual Dysfunction Treatments Additional research found that this hormone acts on the nervous system rather than regulating arousal through the vascular system like medications such as Viagra and Cialis.

cas: 2647-50-9 Flubromazepam lab factory CBNumber: CB12663095 Chemical Name: Flubromazepam Molecular Formula: C15H10BrFN2O Formula Weight: 333.16 CAS No.: 2647-50-9 Flubromazepam is a benzodiazepine derivative which was first synthesized in 1960,but was never marketed and did not receive any further attention or study until late 2012 when it appeared on the grey market as a novel designer drug. It is a structural analog of phenazepam in which the chlorine atom has been replaced by a fluorine atom. An alternate isomer, 5-(2-bromophenyl)-7-fluoro-1,3-dihydro-2H-1,4-benzodiazepin-2-one or "iso-flubromazepam",[9] may have been sold under the same name.

cas: 95958-84-2 Etonitazepyne Protonitazene FIubromazepam BUTONITAZENE Butoxynitazene CBNumber: CB59001825 Chemical Name: 1H-Benzimidazole-1-ethanamine, N,N-diethyl-5-nitro-2-[(4-propoxyphenyl)methyl]- Molecular Formula: C23H30N4O3 Formula Weight: 410.51 CAS No.: 95958-84-2

cas: 2489876-37-9 GMB-475 GMB475 factory CBNumber: CB05494743 Chemical Name: GMB-475 GMB475 Molecular Formula: C43H46F3N7O7S Formula Weight: 861.94 CAS No.: 2489876-37-9 GMB-475 is a proteolysis-targeting chimera (PROTAC) that allosterically targets BCR-ABL1 protein and recruit the E3 ligase Von Hippel-Lindau (VHL), resulting in ubiquitination and subsequent degradation of the oncogenic fusion protein. GMB-475 induces rapid proteasomal degradation and inhibition of downstream biomarkers, such as STAT5 in both human CML K562 cells and murine Ba/F3 cells expressing BCR-ABL1. GMB-475 inhibits the proliferation of certain clinically relevant BCR-ABL1 kinase domain point mutants and further sensitizes Ba/F3 BCR-ABL1 cells to inhibition by imatinib, while demonstrating no toxicity toward Ba/F3 parental cells GMB 475 is a BCR-ABL1 kinase PROTAC® Degrader. Induces degradation of BCR-ABL1 and cABL1, inhibits downstream STAT5 signaling and suppresses cell proliferation in chronic myeloid leukemia cells lines. Chronic myeloid leukemia is a myeloproliferative disorder characterized by the presence of the oncogenic fusion protein BCR-ABL1. ABL1, one of the fusion partners in the BCR-ABL1 protein, contains an allosteric myristoylation binding site. Especially, the proteolysis targeting chimera (PROTAC) technology provides a unique toolkit for probing the non-kinase roles of proteins in a cellular context without resorting to genetic modification of the system. Particularly, PROTACs are heterobifunctional molecules that recruit an E3 ligase to a target protein. In this study, George M. Burslem, et al further investigate the potential of a new series of PROTACs, utilizing an allosteric inhibitor (GNF-5) to degrade BCR-ABL1 protein. ABL1 tyrosine kinase inhibitors (TKIs) effectively reduce kinase activity and downstream signaling of BCR-ABL1. George M. Burslem, et al developed a series of PROTACs. In particular, PROTACs allosterically target BCR-ABL1 protein and recruit the E3 ligase Von Hippel Lindau (VHL). Consequently, this effect results in ubiquitination and subsequent degradation of the oncogenic fusion protein. Typically, the lead compound is GMB-475. Moreover, in both human CML K562 cells and murine Ba/F3 cells expressing BCR-ABL1, GMB-475 induces rapid proteasomal degradation and inhibition of downstream biomarkers. Notably, GMB-475 inhibits the proliferation of certain clinically relevant BCR-ABL1 kinase domain point mutants. Importantly, GMB-475 reduces viability and increases apoptosis in primary chronic myeloid leukemia CD34+ cells, with no effect on healthy CD34+ cells. Furthermore, GMB-475 degrades BCR-ABL1 and reduces cell viability in primary chronic myeloid leukemia stem cells.

cas: 1208070-53-7 TLB-150 TLB150 Benzoate suppliers CBNumber:CB47246717 Chemical Name:TLB 150 Benzoate Molecular Formula:C27H20ClN5O3 Formula Weight:497.93 CAS No.:1208070-53-4

cas: 606101-58-0 MK-0773 MK0773 factory Manufactory supplier lab laboratory wholesaler retailer CBNumber: CB12516577 Chemical Name: MK-0773 Molecular Formula: C27H34FN5O2 Formula Weight: 479.59 CAS No.: 606101-58-0

cas: 28910-89-6 Alprazolam USP Related Compound A CBNumber: CB8761488 Chemical Name: 2-(2-ACETYLHYDRAZINO)-7-CHLORO-5-PHENYL-3H-1,4-BENZODIAZEPINE Molecular Formula: C17H15ClN4O Formula Weight: 326.78 CAS No.: 28910-89-6

cas: 87913-26-6 bromantane CBNumber: CB1150889 Chemical Name: N-(2-ADAMANTYL)-N-(4-BROMOPHENYL)AMINE Molecular Formula: C16H20BrN Formula Weight: 306.24 CAS No.: 87913-26-6

cas: 4350-09-8 5-HTP 5-Hydroxytryptophan L-5-Hydroxytryptophan 5-hydroxytryptophan (5-HTP) can be converted to serotonin in the body. It is often used for depression. It has less evidence for insomnia and anxiety. 5-HTP is a chemical byproduct of the protein building block L-tryptophan. It is produced commercially from the seeds of an African plant known as Griffonia simplicifolia. 5-HTP works in the brain and central nervous system by increasing the production of the chemical serotonin. Serotonin can affect sleep, appetite, temperature, sexual behavior, and pain sensation. Since 5-HTP increases serotonin levels, it is used for conditions in which serotonin is believed to play an important role. These include depression, anxiety, and many other conditions, but there is no good scientific evidence to support most of these uses.

cas: 2558-30-7 N-Desmethylflunitrazepam Fonazepam CBNumber: CB9780606 Chemical Name: N-DESMETHYLFLUNITRAZEPAM Molecular Formula: C15H10FN3O3 Formula Weight: 299.26 CAS No.: 2558-30-7

cas: 694-87-1 benzocyclobutene CBNumber: CB7663345 Chemical Name: Benzocyclobutene Molecular Formula: C8H8 Formula Weight: 104.15 CAS No.: 694-87-1

cas: 64194-69-0 Alprazafone CBNumber: CB910802727 Chemical Name: Alprazafone Molecular Formula: C19H18ClN5O2 Formula Weight: 383.83 CAS No.: 64194-69-0

cas: 687608-35-1 Alpravizafone CBNumber: CB710837383 Chemical Name: Alpravizafone Molecular Formula: C23H27ClN6O2 Formula Weight: 454.95 CAS No.: 687608-35-1

cas: 448-19-1 4-Fluoro-2-methoxy-1-nitrobenzene 5-Fluoro-2-nitroanisole CBNumber: CB0707512 Chemical Name: 5-Fluoro-2-nitroanisole Molecular Formula: C7H6FNO3 Formula Weight: 171.13 CAS No.: 448-19-1

cas: 7148-51-8 Androst-16-en-3-ol CBNumber: CB2381613 Chemical Name: Androst-16-en-3-ol 16,(5-ALPHA)-ANDROSTEN-3-BETA-OL Molecular Formula: C19H30O Formula Weight: 274.44 CAS No.: 7148-51-8 5-α-androst-16-en-3-α-ol (androstenol) is an androgen believed to act as a pheromone. Androstenol has been used in a study to develop a combined gas chromatography/thermal conversion/isotope ratio mass spectrometry (GC/TC/IRMS) method for D/H ratio determination of endogenous urinary steroids.