Gastroenterologie

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Mapping of a target region of allelic loss to a 0.5-cM interval on chromosome 22q13 in human colorectal cancer Article Full-text available November 1999 Antoni CastellsYasushi InoDavid N. Louis[...]Anil K. Rustgi Chromosomal allelic losses have a varying frequency in colorectal cancer. The aim of this study was to define the target region of allelic loss on chromosome 22q in human colorectal carcinogenesis. Fifty-seven pairs of matched normal colonic mucosa and tumor s​p​e​ … Read more 20 Reads47 Citations Download Recommend Follow Share Fatal Non-01 Vibrio cholerae Septicemia in Chronic Lymphocytic Leukemia Article December 1982 Mark I. SiegelArvey I. Rogers The potential of non-01 Vibrio cholerae as human pathogens is assuming greater clinical importance. They are also capable of producing a spectrum of illness that is not confined to the gastrointestinal or biliary tracts. We report a case of fatal non-01 Vibrio cholerae s​e​p​ … Read more 11 Reads26 Citations Recommend Follow Share Interaction of enteropathogenic Escherichia coli 0111 with rabbit intestinal mucosa in vitro Article May 1989 H EmbayeRoger BattJon Richard Saunders[...]C.A. Hart A model system using rabbit intestinal mucosal explants has been developed to examine the characteristic ultrastructural damage to the brush border induced by enteropathogenic Escherichia coli 0111. In this model, as in others, bacterial adherence to the m​i​c​r​o​v​i​l​l​ … Read more 10 Reads34 Citations Recommend Follow Share Diarrhea Caused by Escherichia Coli Serotype 0127: B8; Microbiologic and Clinical Aspects Article August 1959 George M. EisenbergAlfred P. SpivackWilliam Weiss[...]Harrison F. Flippin 11 Reads2 Citations Recommend Follow Share Modulation of host response to Escherichia coll 0157:H7 infection by anti-CD18 antibody in rabbits Article July 1994 Elizabeth J ElliottZhe LiCameron Bell[...]Edward O'Loughlin Escherichia coli O157:H7 infection induces diarrhea, severe colitis, and colonic electrolyte transport abnormalities characterized by decreased Na absorption and Cl secretion. The aim of this study was to examine the role of the host inflammatory response in inducing d​i​s​ … Read more 51 Reads55 Citations Recommend Follow Share Studies in gnotobiotic piglets on Non-0157:H7 Escherichia coli serotypes isolated from patients with hemorrhagic colitis Article April 1988 Saul TziporiKaye I. WachsmuthJane SmithersCraig Jackson A number of verotoxin-producing Escherichia coli strains isolated from sporadic cases of hemorrhagic colitis in the United States over the last 5 yr were shown to belong to serogroups other than O157:H7-the serotype originally implicated in this disease. Experimental i​ … Read more 18 Reads58 Citations Recommend Follow Share MLN-02 in IBD: is "super-selective" really super? Article June 2006 Russell Cohen 13 Reads1 Citation Recommend Follow Share Clostridium difficile Infection Caused by the Epidemic BI/NAP1/027 Strain Literature Review June 2009 Jennifer R O'ConnorStuart JohnsonDale N Gerding Rates and severity of Clostridium difficile infection (CDI) in hospitals in North America and Europe have increased since 2000 and correlate with dissemination of an epidemic strain characterized by higher than usual toxin A and B production, the presence of a third toxin, binary t​o​ … Read more 689 Reads324 Citations Recommend Follow Share Association of gastric adenocarcinoma with the HLA class II gene DQB1*0301 Article September 1996 J E LeeAndrew LowyWA Thompson[...]J D Reveille The HLA class II gene DQB1*0301 has been linked to several cancers. This study was designed to determine if HLA-DQB1*0301 is present at altered frequency in patients with gastric, colorectal, or pancreatic adenocarcinoma. Oligotyping for HLA-DQB1*0301 was performed for 1​5​ … Read more 17 Reads103 Citations Recommend Follow Share Human risk allele HLA-DRB1*0405 predisposes class II transgenic Ab0 NOD mice to autoimmune pancreatitis Article March 2010 Tobias L FreitagCandace M ChamHsiang-Hsuan Sung[...]Grete Sønderstrup Autoimmune pancreatitis (AIP) underlies 5%-11% of cases of chronic pancreatitis. An association between AIP and the human leukocyte antigen (HLA)-DRB1*0405/DQB1*0401 haplotype has been reported, but linkage disequilibrium has precluded the identification of predisposing … Read more 99 Reads25 Citations Recommend Follow Share Effects of OKY 046, a thromboxane-synthase inhibitor, on renal function in nonazotemic cirrhotic patients with ascites Article July 1988 Paolo GentiliniGiacomo LaffiElisabetta Meacci[...]Gianpiero Buzzelli To assess the possible role of increased renal thromboxane A2 (TXA2) synthesis in nonazotemic patients with cirrhosis and ascites and to establish the potential beneficial effect of inhibitors of renal TXA2 production in this clinical setting, we administered OKY 046, a selective T​ … Read more 11 Reads42 Citations Recommend Follow Share The HLA alleles DRB1*13 and DQB1*06 are associated to Whipple's disease Article June 2009 Miryam MartinettiFederico BiagiCa Badulli[...]Gino R Corazza Whipple's disease is a systemic, chronic, relapsing disorder caused by a combination of environmental (Tropheryma whipplei) and unknown host factors. Because it is a rare disease, the association between HLA type and Whipple's disease has been studied in only s​m​a​l​l​ … Read more 68 Reads96 Citations Recommend Follow Share Correlation of symptoms, age, sex, and habitus with cholecystographic findings in 1,000 consecutive examinations Article June 1957 C L HINKELG A MOLLER Most of the patients in this study were referred for cholecystography with complaints of excessive belching, gas pains, and selective dyspepsia. There was no correlation between these symptoms and the cholecystographic findings. Excessive gas, vague upper abdominal pain, h​i​s​t​ … Read more 4 Reads23 Citations Recommend Follow Share Cirrhosis After Repeated Trichloroethylene and 1,1,1-Trichloroethane Exposure Article November 1982 Dwain L. ThieleEdwin H. EigenbrodtAthol J. Ware Acute hepatotoxicity has been described in patients exposed to either trichloroethylene or 1,1,1-trichloroethane, but there have been previous reports of chronic liver disease induced by these agents. We describe a patient who developed cirrhosis and portal hypertension a​f​t​e​r​ … Read more 22 Reads34 Citations Recommend Follow Share Cellular proliferation in proximal and distal rat colon during 1,2-Dimethylhydrazine-induced carcinogenesis Article September 1988 Thomas McGarrityLaurence PeifferPamela Colony Sequential changes in proliferative parameters in proximal and distal colonic crypts were studied during 1,2-dimethylhydrazine-induced carcinogenesis using [3H]thymidine autoradiography as a probe. 1,2-dimethylhydrazine (20 mg/kg) and vehicle (ethylenediaminetetraacetic a​c​i​ … Read more 10 Reads45 Citations Recommend Follow Share Comparison of resistant starch with cellulose diet on 1,2-dimethylhydrazine-induced colonic carcinogenesis in rats Article January 1996 J SakamotoS NakajiK Sugawara[...]A Munakata Epidemiological and experimental studies have shown that dietary fiber may prevent colon cancer. Resistant starch, like dietary fiber, is not subject to digestion in the small intestine. However, it is unknown whether resistant starch inhibits colonic carcinogenesis. In vitro studies h​a​ … Read more 19 Reads69 Citations Recommend Follow Share Enhancement of 1,2-dimethylhydrazine-induced rectal carcinogenesis following chronic ethanol consumption in the rat Article June 1984 H K SeitzP CzyganR Waldherr[...]B Kommerell The incidence, distribution, size, and histopathology of grossly visible intestinal tumors induced by the parenteral administration of 1,2-dimethylhydrazine dihydrochloride were examined in 32 paired rats fed a nutritionally adequate liquid diet containing 36% of total calories either as … Read more 2 Reads87 Citations Recommend Follow Share Effects of small bowel transection, resection, or bypass in 1,2-dimethylhydrazine-induced rat intestinal neoplasia Article May 1983 Charles H. ScudamoreHugh J. Freeman The incidence, distribution, size, and histopathology of rat small and large bowel tumors induced by sequential administration of 1,2-dimethylhydrazine followed by either small bowel resection, 50% jejunoileal resection, or 50% jejunoileal bypass were examined in addition to m​e​ … Read more 5 Reads39 Citations Recommend Follow Share The PREM(1,2,6) model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history Article January 2011 Fay KastrinosEwout W SteyerbergRowena Mercado[...]Sapna Syngal We developed and validated a model to estimate the risks of mutations in the mismatch repair (MMR) genes MLH1, MSH2, and MSH6 based on personal and family history of cancer. Data were analyzed from 4539 probands tested for mutations in MLH1, MSH2, and MSH6. A m​ … Read more 147 Reads174 Citations Recommend Follow Share Adaptive Response of Humans to Changes in Dietary Calcium: Relationship Between Vitamin D Regulated Intestinal Function and Serum 1,25-Dihydroxyvitamin D Levels Article March 1983 Daniel BikleRobert H. HermanSam Hull[...]Bernard Halloran We developed intestinal biopsy procedures in chicks that were extended to humans to study the role of vitamin D in regulating intestinal adaptation to dietary calcium. By comparing biopsy specimens from rachitic chicks (D-) to those from vitamin D-supplemented chicks (​D​ … Read more 13 Reads9 Citations Recommend Follow Share Inhibitory effect of 22-Oxa-1,25-dihydroxyvitamin D3 on the proliferation of pancreatic cancer cell lines Article May 1996 Shigeyuki KawaK YoshizawaM Tokoo[...]Kenichi Furihata Effective chemotherapy for pancreatic cancer is urgently needed. The aim of this study was to compare the anti-proliferative activity of a new vitamin D3 analogue, 22-oxa-1,25-dihydroxyvitamin D3 (22-oxa-calcitriol), on pancreatic cancer cells lines with that of 1,25-d​i​h​y​d​r​o​x​y​v​i​t​a​ … Read more 12 Reads77 Citations Recommend Follow Share Hypercalcemia due to endogenous overproduction of 1,25-dihydroxyvitamin D in Crohn's disease Article June 1998 Xavier Bosch Hypercalcemia may occur in various granulomatous diseases. Two patients with Crohn's disease who had hypercalcemia, hypercalciuria, and excessively high serum levels of 1,25-dihydroxyvitamin D [1,25(OH)2D] are described. Both had numerous noncaseating, e​ … Read more 64 Reads46 Citations Recommend Follow Share Altered Oligosaccharide Structures Reduce Colitis Induction in Mice Defective in beta-1,4-Galactosyltransferase Article February 2012 Shinichiro ShinzakiHideki IijimaHironobu Fujii[...]Eiji Miyoshi Oligosaccharide modifications induce various functional changes in immune cells. The galactose-deficient fraction of fucosylated IgG oligosaccharides is increased, whereas that of β-1,4-galactosyltransferase I (B4GalTI) is reduced, in patients with Crohn's disease. We i​n​v​ … Read more 79 Reads27 Citations Recommend Follow Share Experimental Production of Mallory Bodies in Mice by Diet Containing 3,5-Diethoxycarbonyl-1,4-Dihydrocollidine Article July 1982 Hidejiro YokooThomas R. HarwoodDarlene RackerSaima Arak The first experimental production of Mallory bodies was reported by Denk et al. in 1975 in mice fed griseofulvin. We discovered a second chemical capable of producing Mallory bodies in the mouse liver in a manner similar to griseofulvin. Male Swiss albino mice were fed a p​ … Read more 27 Reads54 Citations Recommend Follow Share Loss of Inositol 1,4,5-Trisphosphate Receptors From Bile Duct Epithelia Is a Common Event in Cholestasis Article November 2003 Kazunori ShibaoKeiji HirataMarie E RobertMichael H Nathanson Cholestasis is one of the principal manifestations of liver disease and often results from disorders involving bile duct epithelia rather than hepatocytes. A range of disorders affects biliary epithelia, and no unifying pathophysiologic event in these cells has been identified as the c​a​u​s​ … Read more 70 Reads104 Citations Recommend Follow Share Secretagogues cause ubiquitination and down-regulation of inositol 1,4,5-trisphosphate receptors in rat pancreatic acinar cells Article June 1999 Richard J.H. WojcikiewiczStephen A. ErnstDavid Yule The action of several exocrine pancreas secretagogues depends on the second messenger inositol 1,4, 5-trisphosphate (IP3), which, via endoplasmic reticulum-located IP3 receptors, mobilizes intracellular Ca2+ stores. Signaling pathways like this one are regulated a​t​ … Read more 11 Reads50 Citations Recommend Follow Share The Type II inositol 1,4,5-trisphosphate receptor can trigger Ca2+ waves in rat hepatocytes Article April 2002 Keiji HirataThomas PuslAllison F O'Neill[...]Michael H Nathanson Ca2+ regulates cell functions through signaling patterns such as Ca2+ oscillations and Ca2+ waves. The type I inositol 1,4,5-trisphosphate receptor is thought to support Ca2+ oscillations, whereas the type III inositol 1,4,5-trisphosphate receptor is thought to initiate Ca2+ … Read more 31 Reads110 Citations Recommend Follow Share Beneficial effect of fructose-1,6-bisphosphate on mitochondrial function during ischemia-reperfusion of rat liver Article July 1995 Wakaba SanoFusao WatanabeHiroshi Tamai[...]Makoto Mino Several groups have reported that administration of fructose-1,6-bisphosphate (FBP) reduces ischemic injury. The aim of this study was to determine the protective effect of FBP on the impairment of mitochondrial oxidative phosphorylation by ischemia-reperfusion i​n​j​u​ … Read more 11 Reads39 Citations Recommend Follow Share The Zinc Finger Protein ZBTB20 Regulates Transcription of Fructose-1,6-Bisphosphatase 1 and β Cell Function in Mice Article February 2012 Ye ZhangAlice XieLuting Zhou[...]Weiping Zhang Fructose-1,6-bisphosphatase (FBP)-1 is a gluconeogenic enzyme that regulates glucose metabolism and insulin secretion in β cells, but little is known about how its transcription is controlled. The zinc finger protein ZBTB20 regulates glucose homeostasis, so we i​n​v​ … Read more 60 Reads33 Citations Recommend Follow Share Proteolytic enzyme activity. I. Urinary proteolytic activity at pH 1.5 in adults Article November 1957 H L SEGALL L MILLERF REICHSMAN[...]G L GLASER 4 Reads5 Citations Recommend Follow Share Proteolytic enzyme activity. II. Gastric and urinary proteolytic activities at pH 1.5 and 3.5 Article November 1957 L L MILLERH L SEGALE J PLUMB 6 Reads6 Citations Recommend Follow Share Pledges of $1.9 Billion at Avian Influenza Conference Article April 2006 Les Lang 5 Reads1 Citation Recommend Follow Share Support for ideas: the last 1000 years and the next ten. The Presidential Address Article October 1983 J T Farrar 2 Reads1 Citation Recommend Follow Share Transvenous liver biopspy. An experience based on 1000 hepatic tissue samplings with this procedure Article September 1982 D LebrecG GoldfarbC Degott[...]J P Benhamou Transvenous liver biopsy was attempted 1033 times in 932 patients in whom percutaneous liver biopsy was contraindicated. A hepatic tissue specimen was obtained in 1000 out of these 1033 attempts. The specimen was unfragmented and/or large enough to allow correct e​v​ … Read more 19 Reads202 Citations Recommend Follow Share Pathologic observations of intrahepatic peribiliary glands in 1000 consecutive autopsy livers: Heterotopic pancreas in the liver Article June 1990 Tadashi TeradaYasuni NakanumaAkira Kakita One thousand consecutively autopsied livers were examined for intrahepatic heterotopic pancreas. Heterotopic pancreas in the liver was found in 41 (4.1%) of the 1000 livers. It occurred with nearly equal frequency in "normal" livers and variously diseased livers. H​i​s​t​o​l​o​g​i​ … Read more 9 Reads76 Citations Recommend Follow Share Multicenter trial of d-α-tocopheryl polyethylene glycol 1000 succinate for treatment of vitamin E deficiency in children with chronic cholestasis Article July 1993 Ronald J SokolNancy ButlerColin Conner[...]Joseph Levy Malabsorption and deficiency of vitamin E causing neurological degeneration are common consequences of chronic childhood cholestatic liver disease. The objective of this study was to determine the long-term efficacy and safety of d-alpha-tocopheryl polyethylene g​l​y​c​ … Read more 64 Reads128 Citations Recommend Follow Share Liver biopsy: Complications in 1000 inpatients and outpatients Article February 1978 Perrault JPDouglas B. McGillBeverly J. OttWilliam F. Taylor We prospectively evaluated risk factors in 1000 consecutive patients who underwent liver biopsy: 829 outpatients and 171 inpatients. The two groups were similar except that the outpatient group had a higher percentage of patients with hepatitis-cirrhosis and a lower percentage … Read more 125 Reads393 Citations Recommend Follow Share Treatment of vitamin E deficiency during chronic childhood cholestasis with oral d-α-tocopheryl polyethylene glycol-1000 succinate Article December 1987 Ronald J SokolJames E HeubiNancy Butler[...]Arnold Silverman Treatment of vitamin E deficiency during chronic childhood cholestasis is hampered by the poor intestinal absorption of available oral preparations of vitamin E when bile flow is severely impaired; thus parenteral vitamin E has been the only effective therapy for many c​h​i​l​ … Read more 42 Reads95 Citations Recommend Follow Share Three Sequencing Companies Join the 1000 Genomes Project Article August 2008 Les Lang 9 Reads4 Citations Recommend Follow Share Phillips, S. F.: Conservation of sodium, chloride, and water by the human colon. Gastroenterology56, 101-108 Article February 1969 Ghislain DevroedeSidney F. Phillips The transport of electrolytes by the human colon has been studied by perfusing the entire colon with isotonic solutions containing different concentrations of sodium, chloride, potassium, and bicarbonate. Absorption of sodium and chloride against large concentration g​r​a​d​i​e​n​ … Read more 13 Reads137 Citations Recommend Follow Share Bile-ology 101 Article August 2001 Richard H. Moseley 5 Reads3 Citations Recommend Follow Share Hamelin R, Flejou J-F, Muzeau F, Potet F, Larent Puig P, Fekete F, Thomas GTP53 gene mutations and p53 protein immunoreactivity in malignant and premalignant Barrett's esophagus. Gastroenterology 107: 1012-1018 Article November 1994 R HamelinJ F FléjouF Muzeau[...]G Thomas Limited data are available regarding TP53 gene alterations in Barrett's esophagus. This study was undertaken to characterize TP53 mutations and p53 protein immunoreactivity in cancers and preinvasive lesions of Barrett's esophageal mucosa. Seventeen Barrett's a​d​e​n​o​c​a​r​c​i​ … Read more 32 Reads146 Citations Recommend Follow Share Unrestricted diet in the treatment of duodenal ulcer. Gastroenterology, 56 (6), 1016-1026 Article July 1969 E BuchmanD T KaungK DolanR N Knapp 5 Reads19 Citations Recommend Follow Share Pisegna JR, Norton JA, Slimak GG, Metz DC, Maton PN, Jensen RT. Effects of curative resection on gastric secretory function and antisecretory drug requirement in the Zollinger-Ellison syndrome. Gastroenterology. 102: 767-778 Article April 1992 Joseph R PisegnaJeffrey A NortonG G Slimak[...]R T Jensen The chronic hypergastrinemia in diseases such as the Zollinger-Ellison syndrome has trophic effects on the gastric mucosa, causing increased parietal cell mass reflected by increased maximal acid output (MAO) and basal acid output (BAO). The time course for the d​e​ … Read more 13 Reads68 Citations

Praxisklinik für Gastroenterologie und Proktologie, Prof. Dr. Thomas Körner Gastroenterologie yaml Copy code January 2006 DOI:10.1007/3-540-31215-3_4 mathematica Copy code In book: PET/CT-Atlas Authors: #Wolfgang Mohnike #Gustav Hör Request Full-text Paper PDF To read the full-text of this research, you can request a copy directly from the authors. Download citation References (116) Abstract In der Vergangenheit fanden nuklearmedizinische Methoden nurzögerlich Eingang in die gastro enterologische Diagnostik (s. Literatur auf CD [➯ 4.1]). In Nachsorge und Rehabilitation von Tumoren des Gastrointestinaltrakts wurden SPECT, PET und PET/CT nicht oder nur approximativ berücksichtigt. ResearchGate Logo Discover the world's research Copy code 25+ million members 160+ million publication pages 2.3+ billion citations Join for free No full-text available Request Full-text Paper PDF To read the full-text of this research, you can request a copy directly from the authors. Peptidrezeptorvermittelte Radiotherapie (PRRT) neuroendokriner Tumoren Article Full-text available yaml Copy code Oct 2004 J. Soeldner #Michael Schmuecking#A Niesen less Copy code #Richard P. Baum View Nuklearmedizinische Diagnostik neuroendokriner Tumoren Article Full-text available less Copy code Jun 2004 M. Hofmann #Richard P. Baum View Limited value of fluorine-18 fluorodeoxyglucose positron emission tomography for the imaging of neuroendocrine tumours Article Full-text available yaml Copy code Dec 1997 #Stefan Adams #Richard P. Baum less Copy code #Thomas Rink#Gustav Hör View The Applications of PET in Clinical Oncology Article Full-text available Copy code May 1991J NUCL MED #Peter S Conti bash Copy code #Ludwig G Strauss View 6-[18F] Fluoro-L-fucose: A Possible Tracer for Assessing Glycoconjugate Synthesis in Tumors with Positron Emission Tomography Article Full-text available Copy code Jan 1991J NUCL MED #Kiichi Ishiwata#Michio Tomura#Tatsuo. Ido bash Copy code #Yoshio Imahori View Expression and localization of somatostatin receptor SSTR1, SSTR2, and SSTR3 messenger RNAs in primary human tumors using in situ hybridization Article Full-text available yaml Copy code Aug 1994 #Jean Claude Reubi#Jean-Claude Schaer#Beatrice Waser bash Copy code #Guadalupe Mengod View Does FDG uptake measure proliferative activity of human cancer cells? In vitro comparison with DNA flow cytometry and tritiated thymidine uptake Article Full-text available Copy code Apr 1993J NUCL MED #Kotaro Higashi#Anaira C. Clavo bash Copy code #Richard L Wahl View Overexpression of glucose transporter 1 and increased FDG uptake in pancreatic carcinoma Article Full-text available less Copy code Sep 1997J NUCL MED #K. G. Grillenberger #Gerhard Glatting#H. G. Beger#S N Reske