DOM D’AGNOSTINO 6 | KETONE BODIES…suppress cancer-causing metabolic pathways

http://www.DoctorsToTrust.com
presents episode 359 | Dr Dom D’Agnostino
of CrossFit conference presentation

Changing metabolic physiology to...
-change brain energy metabolism,
-target the Warburg Effect

These studies show the benefits of a diet...
-and administration of a metabolite that
your body makes (ketones)

These studies show the benefits of a diet...
-and administration of a metabolite that
your body makes (ketones)

Enhanced tumor-associated
immunity
-supported by ketones

These studies show the benefits of a diet...
-antianglogenic & proapoptotic effect
(fighting blood vessels in tumors
&
disassembly of the tumor)
-especially in context of
periodic caloric restriction

Study by Dr D'Agnostino...
-effects of BHB on suppressing
-inflammatory pathways
-that drive cancer growth
(NLRP3 inflammasome)

"Ketones suppress this pathway"

Ketogenic diet...
-much more appreciation for
the types of fats that
can make up the diet
-does NOT HAVE TO BE AS STRICT
(90% fat)
-75% fat is being used clinically now
- drugs that mimic ketosis

Drugs...
-2-DG (2-deoxy-D-glucose)
-3-BP (3-bromopyruvate)
-lonidamine
-metformin

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ketonutrition.org

Original Youtube: https://youtu.be/Hs0zzox-TF0

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