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Επιστημονικά όσα λέει ο Δεσπότης του Πειραιά;;; / Synthetic Genome, Gene Reverse Transcription, Protein Scaffolding, Emergency Authorisation
Talk with Arch. Fr. Paisios Papadopoulos and Associate Professor Dr. Ioannis Kypraios (AI for Healthcare and Translational Medicine), UK on 06.11.21.

UK Gov Emergency Authorisation of Vaccines:
[1] BioNTech SE, A Trial Investigating the Safety and Effects of Four BNT162 Vaccines Against COVID-2019 in Healthy and Immunocompromised Adults. Clinical Trials. [Online] 06th November 2021. Available at:
https://clinicaltrials.gov/ct2/show/NCT04380701

Synthetic Genome:
[1] Wang, H., Li, X., Li, T., Zhang, S., Wang, L., Wu, X., & Liu, J. (2020). The genetic sequence, origin, and diagnosis of SARS-CoV-2.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, Vol.39, No.9, pp.1629–1635, 2020.
[2] Yadav, T., Srivastava, N., Mishra, G., Dhama, K., Kumar, S., Puri, B., & Saxena, S. K. Recombinant vaccines for COVID-19. Human vaccines & immunotherapeutics, Vol.16, No.12, pp.2905–2912, 2020.
[3] Special Report, Garde, D., Saltzman, J., (10th November 2020). "The story of mRNA: How a once-dismissed idea became a leading technology in the Covid vaccine race.", [Online] 06th November 2021. Available at:
https://www.statnews.com/2020/11/10/the-story-of-mrna-how-a-once-dismissed-idea-became-a-leading-technology-in-the-covid-vaccine-race/

Gene Transcription and Reverse Transcription:
[1] Clancy, S. & Brown, W. Translation: DNA to mRNA to Protein. Nature Education, Vol.1(1):101, 2008.
[2] Pray, L. The Biotechnology Revolution: PCR and the Use of Reverse Transcriptase to Clone Expressed Genes. Nature Education Vol.1(1):94, 2008.
[3] Zhang, L., Richards, A., Barrasa, M. I., Hughes, S. H., Young, R. A., Jaenisch, R., Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues. Proc. of the Nat Acad Sci, Vol.118, No.21, 2021.

Nanolipids:
[1] Negi, J. S. "Chapter 6 - Nanolipid Materials for Drug Delivery Systems: A Comprehensive Review." Elsevier, Ed(s): Shyam S. Mohapatra, Shivendu Ranjan, Nandita Dasgupta, Raghvendra Kumar Mishra, Sabu Thomas, In Micro and Nano Technologies, Characterization and Biology of Nanomaterials for Drug Delivery, pp.137-163, 2019.
[2] Nandwana, V., Singh, A., You, M. M., Zhang, G., Higham, J., Zheng, T.S., Li, Y., Prasadd, P. V., Dravid, V.P. Magnetic lipid nanocapsules (MLNCs):
self-assembled lipid-based nanoconstruct for non-invasive theranostic applications. J. Mater. Chem. B, Vol.6, pp.1026-1034, 2018.

Magnetic Nanoparticles:
[1] Trafton, A., (26th April 2019). Nanoparticles take a fantastic, magnetic voyage Tiny robots powered by magnetic fields could help drug-delivery nanoparticles reach their targets. [Online] 6th November 2021. Available at:
https://news.mit.edu/2019/nanoparticles-magnetic-robots-0426

[2] Kim,E., Jeon, S., An, H.-K., Kianpour, M., Yu, S.-W., Kim, J-Y., Rah, J.-C., Choi, H. A magnetically actuated microrobot for targeted neural cell
delivery and selective connection of neural networks. Science Advances, Vol.6, No.39, 2020.

Digital Watermarking for Synthetic Genome:
[1] Clelland, C., Risca, V. & Bancroft, C. Hiding messages in DNA microdots. Nature, Vol.399, pp.533–534, 1999.
[2] Heider, D., Barnekow, A. DNA watermarks: A proof of concept. BMC Molecular Biol, Vol.9, No.40, 2008.
[3] Liss M, Daubert D, Brunner K, Kliche K, Hammes U, Leiherer A, Wagner, R. Embedding Permanent Watermarks in Synthetic Genes. PLoS ONE, Vol.7(8): e42465, 2012.

Protein Scaffolding:
[1] Dokland, T. Scaffolding proteins and their role in viral assembly. Cell Mol Life Sci., Vol.56(7-8), pp.580-603, 1999.

NHS/NICE Phychosomatic Effects:
[1] Spillane A., Larkin C., Corcoran P., Matvienko-Sikar K., Riordan F., Arensman E. Physical and psychosomatic health outcomes in people bereaved by suicide compared to people bereaved by other modes of death: a systematic review. BMC Public Health. Vol.17(1):939, 2017.
[2] Rundell, J., et al. (version 11). Traumatic Stress Disorders in Medically Ill Patients An Evidence-Based Medicine (EBM) Monograph for Psychosomatic Medicine Practice. The Guidelines and Evidence-Based Medicine Subcommittee of the Clinical Practice Committee, Academy of Psychosomatic Medicine (APM) and The European Association of Psychosomatic Medicine (EAPM), May 2013.
Web URL:
https://www.eapm.eu.com/wp-content/uploads/2018/06/PTSD_APM-EAPM-Monograph.pdf

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