Scientists say some coronavirus vaccines under trial need screening for raising HIV risk

A group of researchers have sounded the alarm about a method being used to build some experimental Covid-19 vaccines, saying it could increase the risk of HIV infection in populations seen as vulnerable to the virus that causes Aids.Show more

Some vaccines use what is known as a viral vector, or a modified virus that delivers the vaccine’s genetic material into the body’s cells. One vector, a cold virus known as adenovirus 5 (Ad5), is being used in two Covid-19 vaccines in advanced trials – one by Chinese company CanSino Biologics and another by Russia’s Gamaleya Research Institute.

But four scientists who ran international trials of an HIV vaccine candidate using Ad5 over a decade ago found it increased the risk of HIV infection for certain men. The researchers are concerned the same risks remain.
(South China Morning Post - Simone McCarthy)

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