Typhoid Mary

2 years ago
70

Original Publication Date: August 15, 2021

Original YouTube Description: In this video, I'm taking a look at Mary Mallon, AKA "Typhoid Mary", who was credited with infecting 53 people with Typhoid fever and killing 3 of them, despite never having the disease herself.

The original paper by George Soper:
https://sci-hub.st/10.1001/jama.1907.25220500025002d

A retrospective published by Soper in 1939:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1911442/?page=1

An editorial published at the time of her death:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1529062/?page=1

A JAMA paper on Typhoid carriers from 1933:
https://sci-hub.do/10.1001/jama.1933.02740230044012

A modern paper on Typhoid carriers from 2014:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252485/

The 2019 paper on a PCR test for differentiating typhoidal and non-typhoidal strains of salmonella, just to show how hard it is even today:
https://www.biorxiv.org/content/10.1101/537654v1.full.pdf

I don't mention it in the video, but the Widal Test was used to show that Mallon was positive for Typhoid bacteria. It has lots of problems:
https://pmj.bmj.com/content/76/892/80

The Wikipedia article:
https://en.wikipedia.org/wiki/Mary_Mallon

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