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This subsection focuses on anthropogenic forms of wildlife destruction. The loss of animals from ecological communities is also known as defaunation.[16]

Exploitation of wild populations has been a characteristic of modern man since our exodus from Africa 130,000 – 70,000 years ago. The rate of extinctions of entire species of plants and animals across the planet has been so high in the last few hundred years it is widely believed that we are in the sixth great extinction event on this planet; the Holocene Mass Extinction.[17][18][19] The 2019 Global Assessment Report on Biodiversity and Ecosystem Services, published by the United Nations' Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services, says that roughly one million species of plants and animals face extinction within decades as the result of human actions.[20][21]

Destruction of wildlife does not always lead to an extinction of the species in question, however, the dramatic loss of entire species across Earth dominates any review of wildlife destruction as extinction is the level of damage to a wild population from which there is no return.[clarification needed]

The four most general reasons that lead to destruction of wildlife include overkill, habitat destruction and fragmentation, impact of introduced species and chains of extinction.[22

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