Dr. Money And The Boy With No Penis.

David Reimer (birth name: Bruce Reimer, born: August 22, 1965 -- died [suicide]: May 4, 2004) was born as a healthy male, but was sexually reassigned and raised as female after his penis was accidentally destroyed during circumcision. Psychologist John Money oversaw the case and reported the reassignment as successful, and as evidence that gender identity is primarily learned. Academic sexologist Milton Diamond later reported that Reimer never identified as female, and that he began living as male at age 15. Reimer later went public with his story to discourage similar medical practices. Eventually he committed suicide, due to suffering years of severe depression.

I wouldn't usually post something from the the BBC OR CBC, this is a fairly well known story in Canada, apart from some of the network's silly editorializing it is accurate.