Russo Brothers Talk Biggest Challenge In Tackling Avengers: Endgame

The director duo opened up about the difference in the most recent issue of Empire Magazine. They began with the most obvious difference, and that has to do with the cast Endgame has to work with.
"Alright, we have no idea how the story can move forward from here. We've just killed half the characters,” Joe Russo stressed.
Writer Stephen McFeely then said the biggest narrative difference comes courtesy of Thanos.