Osteoarthritis Causes, Treatments and Supplements

Osteoarthritis Causes, Treatments and Supplements

A brief investigation about osteoarthritis (OA), a chronic joint condition characterized by pain, stiffness, and functional impairment, particularly in the knees, hips, and hands. We explore various management strategies, focusing heavily on the efficacy and safety of dietary supplements like glucosamine, chondroitin, collagen, turmeric/curcumin, and creatine.

Certain supplements like curcumin may offer comparable pain and function benefits to NSAIDs, particularly in the short term, glucosamine and chondroitin, offer positive results when the product is high quality.

Non-pharmacological approaches are supported by research studies, such as maintaining a healthy weight, engaging in physical activity, and utilizing supportive devices, as crucial for joint health and OA management.

Summary
Osteoarthritis (OA), also known as degenerative joint disease, is the most prevalent type of arthritis, affecting millions of Americans. Unlike inflammatory types of arthritis such as rheumatoid arthritis, OA is primarily characterized by the gradual degeneration and loss of cartilage in the joints. This deterioration leads to bones rubbing together, causing pain, inflammation, stiffness, tenderness, and limited movement. While OA is commonly associated with aging, often appearing around ages 45-50 and affecting 35% of adults over 65, it can also affect younger individuals. Common joints affected include the knees, hips, hands, feet, and spine.

References

HPCS Highly Purified Chondroitin Sulfate Pharmaceutical Grade for osteoarthritis
https://pmc.ncbi.nlm.nih.gov/articles/PMC5561371/

UC II Un-denatured Type II Collagen Unflavored 40mg capsule for osteoarthritis
https://pmc.ncbi.nlm.nih.gov/articles/PMC9210509/

Creatine for osteoarthritis
https://pubmed.ncbi.nlm.nih.gov/21311365/
https://pmc.ncbi.nlm.nih.gov/articles/PMC6518405/

Celecoxib COX-2 inhibitor and nonsteroidal anti-inflammatory drug 200 mg orally once daily or 100 mg orally twice daily for osteoarthritis
https://pubmed.ncbi.nlm.nih.gov/10560596/

HA hyaluronic acid oral for osteoarthritis
https://pmc.ncbi.nlm.nih.gov/articles/PMC11778613/

Diacerein for osteoarthritis
https://pmc.ncbi.nlm.nih.gov/articles/PMC10712695/

ASU powder from Avocados Soybean Unsaponifiables for osteoarthritis
https://pmc.ncbi.nlm.nih.gov/articles/PMC7023362/

Tumeric Curcumin for osteoarthritis
https://pmc.ncbi.nlm.nih.gov/articles/PMC11959387/

Effectiveness of collagen supplements in patients with osteoarthritis. Systematic review
https://www.researchgate.net/publication/383208865_Effectiveness_of_collagen_supplements_in_patients_with_osteoarthritis_Systematic_review

Can Collagen Supplements Help Arthritis?
https://www.arthritis.org/health-wellness/treatment/complementary-therapies/supplements-and-vitamins/can-collagen-supplements-help-arthritis

Role of Collagen Derivatives in Osteoarthritis and Cartilage Repair: A Systematic Scoping Review With Evidence Mapping
https://pmc.ncbi.nlm.nih.gov/articles/PMC7695755/

Beneficial Effect of Creatine Supplementation in Knee Osteoarthritis
https://journals.lww.com/acsm-msse/Fulltext/2011/08000/Beneficial_Effect_of_Creatine_Supplementation_in.20.aspx

Beneficial effect of creatine supplementation in knee osteoarthritis
https://pubmed.ncbi.nlm.nih.gov/21311365/

Exercise, and Creatine in Knee Osteoarthritis
https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.2019.33.1_supplement.769.4

Collagen Supplementation for Joint Pain and Arthritis
https://www.nutritionalphysicaltherapy.com/blog/collagen-supplementation-for-joint-pain-and-arthritis

Easing The Discomfort: Creatine And Osteoarthritis
https://trycreate.co/blogs/news/easing-the-discomfort-creatine-and-osteoarthritis

Does Creatine Improve Arthritis Symptoms?
https://jarretmorrow.com/2011/02/14/creatine-supplementation-reduce-osteoarthritis-symptoms/

Do supplements help with the symptoms of osteoarthritis?
https://www.medicalnewstoday.com/articles/supplements-for-osteoarthritis

Dietary Supplements as Disease-Modifying Treatments in Osteoarthritis: A Critical Appraisal
https://pmc.ncbi.nlm.nih.gov/articles/PMC4103717/

Effects of dietary supplements on patients with osteoarthritis: A systematic review and network meta-analysis
https://www.sciencedirect.com/science/article/abs/pii/S2095496425000536

Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis
https://bjsm.bmj.com/content/52/3/167

Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis
https://pubmed.ncbi.nlm.nih.gov/29018060/

Nutritional Supplements and Osteoarthritis
https://www.webmd.com/osteoarthritis/nutritional-supplements-osteoarthritis

Supplements for the Treatment of Osteoarthritis
https://www.ucdenver.edu/docs/librariesprovider65/clinical-services/sports-medicine/supplements-for-the-treatment-od-osteoarthritis.pdf?sfvrsn=81345bb9_2