Antimicrobial Resistance From Space: The ISS Bacterial Threat

The International Space Station has developed a unique microbial ecosystem during its 23+ years of continuous habitation, where bacteria are evolving antimicrobial resistance at accelerated rates. Research shows that bacteria in space develop resistance through novel mechanisms triggered by microgravity, increased radiation, and the closed-system environment. These space-adapted microbes form thicker biofilms, alter their membrane composition, and exhibit horizontal gene transfer rates 24 times higher than on Earth. The "spaceflight phenotype" encompasses increased virulence and activation of stress-response genes. While these evolved bacteria present potential biosecurity concerns upon return to Earth, they've also created opportunities for medical advancement. Scientists are using data from space-evolved bacteria to develop new antibiotic approaches and biomimetic materials. This emerging field of "astromicrobiology" represents both a challenge for space exploration safety and a promising avenue for addressing Earth's antimicrobial resistance crisis.

https://www.ihadnoclue.com/article/1118873862888554497