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Finance & Crypto Tech Reviews all in podcast all in podcast all-in podcast Chamath Palihapitiya Jason Calacanis David Sacks David Friedberg

Sep 28, 2025 All-In Summit 2025
(0:00) Introducing Eli Lilly CEO Dave Ricks
(1:43) How Eli Lilly discovered the GLP-1 impact on weight loss, counterfeit products from China
(7:08) GLP-1 pricing and capital allocation after a breakout pharma product
(12:56) Why Biotech VC has plummeted, “patent hacking” in China
(15:32) Dave’s health regimen: good sleep, movement, healthy diet, social relationships, reading
(18:32) Unexpected impacts of GLP-1s, helping with addictions, potential mental health use cases
(21:16) Thoughts on RFK Jr, Big Pharma’s influence on the media, how AI empowers patients
(25:27) Impact of proposed NIH cuts, explaining the “PBM boogeyman”, next major pharma breakthrough

Thanks to our partners for making this happen!

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Polymarket: https://www.polymarket.com/

Athletic Brewing: https://www.athleticbrewing.com/

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