Proof Tylenol Maker KNEW About Pregnancy-Autism Connection

Proof Tylenol Maker KNEW About Pregnancy-Autism Connection

Sept. 29, 2025

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In 2019, a Johns Hopkins study analyzing umbilical cord blood samples found that newborns with the highest exposure to acetaminophen were about three times more likely to be diagnosed with ADHD or autism spectrum disorder in childhood.

A new study from researchers at the Johns Hopkins Bloomberg School of Public Health has found that exposure to acetaminophen in the womb may increase a child's risk for attention deficit hyperactivity disorder or autism spectrum disorder.

The researchers analyzed data from the Boston Birth Cohort, a 20-year study of early life factors influencing pregnancy and child development. They found that children whose cord blood samples contained the highest levels of acetaminophen—the generic name for the drug Tylenol—were roughly three times more likely to be diagnosed with ADHD or autism spectrum disorder later in childhood, compared to children with the lowest levels of acetaminophen in their cord blood.

Their findings were published last week in JAMA Psychiatry.

Previous studies have found an association between maternal use of acetaminophen during pregnancy and increased risks of adverse childhood outcomes, including neurodevelopmental disorders such as ADHD—which is marked by hyperactivity and difficulty paying attention or controlling impulsive behavior—and autism spectrum disorder, a complex developmental disorder that can affect how a person socializes, communicates, and behaves. Because these studies relied on mothers self-reporting their acetaminophen use, critics have said the findings may be affected by recall bias or lack an objective measure of in-utero exposure. As a result, the U.S. Food and Drug Administration has refrained from making recommendations regarding the use of acetaminophen during pregnancy.

"People in general believe Tylenol is benign, and it can be used safely for headaches, fever, aches, and pains," says Xiaobin Wang, a professor in the Bloomberg School's Department of Population, Family, and Reproductive Health and the study's corresponding author. "Our study further supports the concerns raised by previous studies, that there is a link between Tylenol use during pregnancy and increased risk for autism or ADHD."

https://hub.jhu.edu/2019/11/05/acetaminophen-pregnancy-autism-adhd/

https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2753512

Original: https://youtu.be/9Uw4K_CjVL8

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