Autism and Acetaminophen: Unpacking the Link - The Deep Dive NotebookLM

Synthesis of studies over last decade. Pivotal is John's Hopkins' using Boston Cohort.

Based on the below authoritative sources.

Association of Cord Plasma Biomarkers of In Utero Acetaminophen Exposure With Risk of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in Childhood | Child Development | JAMA Psychiatry | JAMA Network
https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2753512

Association of Cord Plasma Biomarkers of in Utero Acetaminophen Exposure with Risk of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in Childhood - Johns Hopkins University
https://pure.johnshopkins.edu/en/publications/association-of-cord-plasma-biomarkers-of-in-utero-acetaminophen-e

Taking Tylenol during pregnancy associated with elevated risks for autism, ADHD | Hub
https://hub.jhu.edu/2019/11/05/acetaminophen-pregnancy-autism-adhd/

NIH-funded study suggests acetaminophen exposure in pregnancy linked to higher risk of ADHD, autism | National Institutes of Health (NIH)
https://www.nih.gov/news-events/news-releases/nih-funded-study-suggests-acetaminophen-exposure-pregnancy-linked-higher-risk-adhd-autism

Acetaminophen’s Role in Autism and ADHD: A Mitochondrial Perspective - PMC
https://pmc.ncbi.nlm.nih.gov/articles/PMC12429359/

Acetaminophen Use for Fever in Children Associated with Autism Spectrum Disorder - PMC
https://pmc.ncbi.nlm.nih.gov/articles/PMC5044872/

Acetaminophen Use During Pregnancy and Children’s Risk of Autism, ADHD, and Intellectual Disability | Attention Deficit/Hyperactivity Disorders | JAMA | JAMA Network
https://jamanetwork.com/journals/jama/fullarticle/2817406

Using acetaminophen during pregnancy may increase children’s autism and ADHD risk | Harvard T.H. Chan School of Public Health
https://hsph.harvard.edu/news/using-acetaminophen-during-pregnancy-may-increase-childrens-autism-and-adhd-risk/

Babies at higher risk for ADHD, autism if pregnant moms took acetaminophen | Hopkins Population Center | Johns Hopkins University
https://popcenter.jhu.edu/2019/10/31/babies-at-higher-risk-for-adhd-autism-if-pregnant-moms-took-acetaminophen/

Mount Sinai Study Supports Evidence That Prenatal Acetaminophen Use May Be Linked to Increased Risk of Autism and ADHD | Mount Sinai - New York
https://www.mountsinai.org/about/newsroom/2025/mount-sinai-study-supports-evidence-that-prenatal-acetaminophen-use-may-be-linked-to-increased-risk-of-autism-and-adhd

Postnatal Acetaminophen and Potential Risk of Autism Spectrum Disorder among Males
https://www.mdpi.com/2076-328X/10/1/26

Evaluation of the evidence on acetaminophen use and neurodevelopmental disorders using the Navigation Guide methodology | Environmental Health | Full Text
https://ehjournal.biomedcentral.com/articles/10.1186/s12940-025-01208-0

Evaluation of the evidence on acetaminophen use and neurodevelopmental disorders using the Navigation Guide methodology - PMC
https://pmc.ncbi.nlm.nih.gov/articles/PMC12351903/

Tylenol Maker Privately Admitted Evidence Was Getting ‘Heavy’ For Autism Risk In 2018
https://dailycaller.com/2025/09/26/scoop-internal-docs-tylenol-maker-janssen-autism-risk/