How I Run Stable Diffusion on AMD Instinct MI60 with Fedora 42 – Complete Walkthrough

Want to run Stable Diffusion (SD.Next) locally on Fedora 42 using your AMD Instinct MI60 GPU? No Docker. No CUDA. 100% open-source and ROCm-powered.

In this screencast, I show you how to:

Set up ROCm 6.3 with Fedora 42

Create a dedicated Python virtual environment on a separate partition (/AI)

Install PyTorch with ROCm support

Run SD.Next completely outside of Docker

Verify GPU acceleration and HIP backend support

This setup delivers blazing fast AI image generation using SD.Next - the next-gen open-source UI for Stable Diffusion.

📝 Read the full blog guide here:
https://ojambo.com/getting-started-with-sd-next-on-fedora-42-using-amd-instinct-mi60

📚 Learning Python Book (Amazon):
https://www.amazon.com/Learning-Python-Programming-eBook-Beginners-ebook/dp/B0D8BQ5X99

🎓 Learning Python Course (Ojambo Shop):
https://ojamboshop.com/product/learning-python

👨‍🏫 1-on-1 Python Tutoring or AI Setup Services
Python tutoring: https://ojambo.com/contact

SD.Next / Stable Diffusion Install & Migration: https://ojamboservices.com/contact

🧠 Want to train models or fine-tune SD? This setup makes it possible.

#StableDiffusion #SDNext #AMDGPU #ROCm #Fedora42 #AIImageGeneration #PyTorch #OpenSourceAI #HIP #AMDINSTINCT