The Underappreciated Role of Carbon Dioxide in Health - Interview with Georgi Dinkov

In this interview, repeat guest Georgi Dinkov reviews the role of carbon dioxide (CO2) in health. CO2 is typically thought of as nothing more than a harmful waste product of respiration, but it’s actually a driver of mitochondrial energy production, and it improves the delivery of oxygen into your cells.

CO2 is typically thought of as nothing more than a harmful waste product of respiration, but it’s actually a driver of mitochondrial energy production, and it improves the delivery of oxygen into your cells.

One of the simplest ways to optimize your CO2 is by breathing properly. Most people tend to over-breathe, which causes you to expel too much CO2. Proper breathing involves breathing less and breathing slower. Both of these allow CO2 to build up, and that appears to be part of why breathwork has such wide-ranging benefits.

To have sufficient CO2 production, you need healthy mitochondria because CO2 is produced exclusively in the Krebs cycle in the mitochondria. If you have mitochondrial dysfunction, if you're hypothyroid or have high levels of inflammation, then you will not be producing enough CO2.

When your CO2 is too low, your body reverts to an “emergency” vasodilator, nitric oxide (NO). Drawbacks of elevated NO include peroxynitrite species formation and pseudohypoxia. NO also damages the polyunsaturated fats (PUFAs) in your cells, and inhibits energy production.

CO2 combats cancer development by lowering the pH of the cell, thereby allowing extra water to be excreted. This is the opposite of linoleic acid (LA) and estrogen, both of which suck water in and cause the cell to swell. Cellular swelling is a feature of cancer cells.

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