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What DNA Methylation Testing Can Tell You About Your Health - Interview with Ryan Smith
Ryan Smith is the founder of TruDiagnostic, a commercial testing system that tests your biological age, as opposed to your chronological age. It's can be a profoundly useful tool, because you need an objective barometer to tell you whether or not the things you're doing to improve your health are actually having the desired impact.
TruDiagnostic is a commercial testing system that determines your biological age, as opposed to your chronological age, by measuring your DNA methylation.
Your genes have promoter sites at the beginning of the DNA strand, and methylation is measured at those sites. The level of methylation at the promoter site correlates to the degree of expression of that particular gene.
Biological aging is a primary cause for chronic disease. If everyone in the world were to be seven years younger biologically than their chronological age, the global disease burden would be reduced by 50%.
Patients who contracted COVID-19 were found to have telomere length shortening, but while people over age 50 showed increased biological aging as a result of the infection, people younger than 50 had the converse effect, actually getting biologically younger.
Among the more exciting antiaging therapies now available are very small embryonic-like stem cells (Vsels), which have shown multiyear age reversals even after a single treatment. Other promising therapies are senolytics and plasma exchange apheresis.
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