A Woman Drank 1 Liter Soy Sauce Colon Cleanse In 2 Hours. This Is What Happened To Her Brain.

The patient in this case presented to an emergency room in Illinois, 2012
Music by Lifeformed ► https://lifeformed.bandcamp.com
These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.
Credits:
Patient CG portrayed by Vanessa Banks-Gonzales
Production Assistant: Bradley Williams
Osmotic Demyelination MRI by Dr Brendon Friesen https://radiopaedia.org/cases/trident-sign-osmotic-demyelination
Celiac Disease Pathology by Dr Michael Bonert
References:
[0] Adams RD et. al. Central Pontine Myelinolysis. AMA Arch Neurol Psychiatry. 1959 Feb;81(2):154-72. https://www.ncbi.nlm.nih.gov/pubmed/13616772
[1] Ismail FY. et. al. Clinical semiology and neuroradiologic correlates of acute hypernatremic osmotic challenge in adults: a literature review. AJNR Am J Neuroradiol. 2013 Dec;34(12):2225-32. https://www.ncbi.nlm.nih.gov/pubmed/23413245
[2] Sterns RH. et. al. Osmotic demyelination syndrome following correction of hyponatremia. N Engl J Med. 1986 Jun 12;314(24):1535-42. https://www.ncbi.nlm.nih.gov/pubmed/3713747
[3] Lien YH. et. al. Study of brain electrolytes and organic osmolytes during correction of chronic hyponatremia. Implications for the pathogenesis of central pontine myelinolysis. J Clin Invest. 1991;88(1):303. https://www.ncbi.nlm.nih.gov/pubmed/2056123
[4] Strange K. Regulation of solute and water balance and cell volume in the central nervous system. J Am Soc Nephrol. 1992;3(1):12. https://www.ncbi.nlm.nih.gov/pubmed/1391705
[5] Leffler DA, Green PH, Fasano A. Extraintestinal manifestations of coeliac disease. Nat Rev Gastroenterol Hepatol 2015;12:561-571. https://www.ncbi.nlm.nih.gov/pubmed/26260366
[6] Bushara KO. Neurologic presentation of celiac disease. Gastroenterology 2005;128:Suppl 1:S92-97 https://www.ncbi.nlm.nih.gov/pubmed/15825133
[7] Fasano A, Catassi C. Celiac disease. N Engl J Med 2012;367:2419-2426 https://www.ncbi.nlm.nih.gov/pubmed/23252527