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Hydrogel nanoparticles, also called nanogels, are small, three-dimensional structures made from crosslinked hydrophilic polymer chains that swell in water. These materials combine the high water content and biocompatibility of hydrogels with the nanoscale properties of nanoparticles. This combination makes them useful for various applications, particularly in drug delivery, tissue engineering, and sensing.
Key Characteristics and Applications:
Hydrogel Properties:
Hydrogels are known for their high water content, which allows them to swell in water, and their biocompatibility, making them suitable for biological applications.
Nanoparticle Properties:
Nanoparticles have a small size (nanoscale), which allows them to access smaller spaces and potentially avoid being cleared by the body's immune system.
Drug Delivery:
Hydrogel nanoparticles can be designed to encapsulate and release drugs in a controlled and targeted manner, improving drug efficacy and reducing side effects.
Tissue Engineering:
They can be used as scaffolds or carriers for cells and growth factors, aiding in tissue regeneration and repair.
Sensing:
Hydrogel nanoparticles can be modified to detect specific molecules or changes in the environment, making them useful in biosensing applications.
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