Shooting From The Hip - 39 - DMT: Dimethyltryptamine

Dimethyltryptamine (DMT) - a tryptamine that occurs in many plants & animals, including humans - DMT is used as a psychedelic drug - various cultures use it ritually

DMT - inhaled, ingested, or injected
its effects depend on the dose, as well as method of administration
inhaled or injected, effects last a short period of time: 5 to 15 minutes - effects can last 3 hours or more when orally ingested along with a monoamine oxidase inhibitor (MAOI) - ayahuasca brew of many native Amazonian tribes
DMT can produce vivid mystical experiences involving euphoria & dynamic pseudohallucinations of geometric forms - Hallmark effect; More Real Than Real
Entity encounters, part animal part human, sometimes formless: interaction dialogue, conversations - accounts of meeting entities, DMT Realm

Tryptamine: - biochemistry a compound, serotonin is a derivative, produced from tryptophan by decarboxylation releases CO2 :Tryptamines act predominantly as hallucinogens - play important biomedical role as neurotransmitter & neuromodulator, vasoconstrictor & vasodilator, antimicrobial & antibacterial, antioxidant & antifungal agents

Rick Strassman - American clinical associate professor of psychiatry-University of New Mexico School of Medicine - held a fellowship in clinical psychopharmacology at the University of California San Diego - Professor of Psychiatry for 11 years at the University of New Mexico - Strassman is 1st person in United States to undertake human research with psychedelic, hallucinogenic, or entheogenic substances dimethyltryptamine (1990 - 1995) - author of DMT: The Spirit Molecule; a summary of academic research into DMT
The Purpose Of Endogenous DMT? - does the brain make DMT (seems to be made in brain, found spinal fluid) - other locations liver, Lungs - speculation DMT maybe neurotransmitter like serotonin, dopamine

Imperial College - leading research institute UK, completely legal study ... 2 Purposes: 1) attempting to map the landscape; literal realm of DMT experience 2) possible therapeutic uses & outcomes: applying to volunteers intravenous DMT

Andrew Gallimore: neurobiologist, pharmacologist & chemist currently based in Tokyo, Japan - he writes about psychedelics as molecular technologies for interfacing with alternate realities & communication with apparently intelligent beings that reside therein - author of Alien Information Theory: Psychedelic Drug Technologies & the Cosmic Game
also forthcoming Reality Switch Technologies: Psychedelics as Tools for the Discovery & Exploration of New Worlds
written both academic & popular articles on DMT & other psychedelic molecules
2015, he collaborated with DMT pioneer Dr. Rick Strassman to develop a model for the repurposing of the target-controlled intravenous infusion technology used in anaesthesiology to allow the DMT state to be safely & stably extended for an indefinite period of time - the hope is this technology will be used to extended experiences in the DMT space/realm for detailed exploration & mapping of that landscape, including experiments & potentially establishing communication contacted intelligent entities

the brain constructs the model of realty; based on sensory information/stimuli from the world we live in & experience in average waking life, the world experienced in dreaming or under the influence of DMT, psychedelic (LSD, Silicon from psilocybin) is always a construct of the brain; considered fundamental - according Gallimore: brain always constructs your world model, it's a world building machine; based on individual neural pattern activity based on stimuli from outside world & how individually interpret those stimuli & experiences - psychedelic's change the world model constructed in the brain (cortex)

so then are you experiencing the outside world or just a mental construct - based on an outside environment

Reality Channel Switch - not just an altered version of the normal waking world environment- but a completely different model of reality - changing reality channel to a different channel reality - conventional explanation the brain is just making it up; a wild fabrication, it's on drugs

the brain has adapted to construct a Single World Model over the course of it's evolution, development within our world environment- it's learned to construct a one world model

then as a result of the introduction of a plant alkaloid; it becomes capable of constructing an entirely coherent inordinately complex hyper-dimensional alien worlds: filled with hyper-intelligent entities -- where & how did it learn to construct these realities (More Real Than Real):

Alkaloid: member large group of chemicals derived from plants - possess potent pharmacologic effects: including- cocaine, nicotine, strychnine, caffeine, morphine, pilocarpine, atropine, methamphetamine, mescaline, ephedrine & tryptamine