The Outer Limits - SE02 EP15 (1965)

"The Brain of Colonel Barham"
When Colonel Barham, a dying astronaut, agrees to have his brain transferred into a computer to lead a manned mission to Mars, the experiment takes a sinister turn. Freed from the limitations of his human body, Barham’s mind grows dangerously powerful, developing telepathic abilities and a thirst for control. As the scientists overseeing the project struggle to contain him, they realize they may have created an unstoppable force.
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