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Opioid radicals in pharmacological substances. Opioid epidemic. Drug Design.
Opioid radicals in the structure of antipsychotics, anxiolytics, anticonvulsants and some others. What bigpharma is hiding.
Drugs And Addiction,
Molecular Biology,
Antipsychotic drugs,
Drug Design,
Benzodiazepines,
Anxiolytics
Let's ask a few important questions that have no answers yet, questions that no one has dared to ask, questions, the answers to which could greatly undermine the reputation of pharmaceutical giants, change the rules for registering pharmaceutical drugs, revise drug access lists and much more. Neuroleptics, anxiolytics, some anticonvulsants and tranquilizers have radicals in their structure that are characteristic of direct opioid mimetics. These are radicals characteristic of meth and leukenkephalins-aromatic nuclei, an amino group at a distance of 2, 3, 5 carbon bonds from the aromatic nucleus, cyclic saturated or heterochemical inclusions, fragments of leucine or methionine (or their pharmacological analogues). All these radicals, when correctly placed, are capable of causing a powerful affinity for opioid receptors. Some antipsychotic.. drugs have a slightly less pronounced similarity to the opioid structure, while others are closer to enkephalins and opiates in structure. The drugs that are closest, in my opinion, in structure to opiates are xanax, pregabalin, coaxil and xylazine. Let's analyze the chemical structure of these drugs and determine, if possible, what differences they have from similar analogs, but with a less dubious history.
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