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Dr. Mark Hyman: "Diabetes reversible, heart disease reversible, Alzheimer's
Dr. Mark Hyman: "Diabetes reversible, heart disease reversible, Alzheimer's, now Richard Isaacson has done amazing work showing how we can reverse Alzheimer's using aggressive lifestyle interventions."
"We've spent, this is a great example about $2 billion and over 400 studies trying to find drugs for Alzheimer's and nothing has worked. The drugs that are approved are extremely expensive, have marginal benefit, a lot of side effects and cost a huge amount of money and may delay your entry into nursing home by two or three months. That's a win. That's not very good."
"Now there's a couple of trials that have been done. The finger trial out in Europe and the pointer trial, which is emerging, that showed aggressive lifestyle intervention, diet, exercise, managing stress, sleep, optimizing all your risk factors. was able to not just slow the progression of Alzheimer's and dementia, but to reverse it. This is published data. This is not my opinion."
"Richard Isaacson also has published this data. And now using biomarkers, and we can actually test with function, soon we'll be adding biomarkers for Alzheimer's. So now there's blood tests for Alzheimer's. So you don't have to wait until you forget your keys. And also for cancer, you're asking about cancer, we do a multi-cancer."
"So on imaging, which is very expensive and difficult and not- Brain imaging. Yeah, brain imaging. You can see the changes up to 30 years before you get Alzheimer's as a symptom. With blood tests, it's not as far as that. We're still figuring out what those times are, but you can see start, these proteins start to develop in the blood that indicate there's something happening and you can then intervene early."
"And the thing about Alzheimer's is that if you intervene early, you can have an incredible benefit to help slow the progression and delay it and actually reverse it. And I've seen this in my patients. I wrote a book about this, the Ultramine solution 15 years ago, the Dale Bredesen's written a book called the End of Alzheimer's and documenting that we have to get through causes."
"I think it's a medical paradigm shift. You know, I think as most doctors are in a world that's flat world, they don't understand that the world is round. We've shifted a paradigm scientifically from a disease-based diagnostic system to understanding the body as an integrated ecosystem. And so the work of people like Lee Ray Hood from the Institute for Systems Biology, his Phenome Project, is mapping out how. our understanding of disease is completely wrong."
"It's based on labeling people according to symptoms and where it is in their body rather than on mechanisms and causes. So I wrote a book called Young Forever, which is about longevity. We talked about it, I think, last time I was on your show. And in the book, I talk about the scientists who come up with this model of what are the root causes of aging?"
"Because we think aging is just, it's gonna happen inevitable. We're gonna get sick, we're gonna get older, we're gonna get frail, we're gonna get weak. and they've identified the underlying biology behind that. So if we cured heart disease and cancer from the face of the planet, we might extend life five to seven years. You can get the same thing with meaning and purpose or playing tennis."
"But if you actually drill with the hallmarks of aging, the things that really go wrong, inflammation, mitochondrial insure, or nutrition, you can act, and your microbiome, all the things that underlie disease, you could extend life by 30 or 40 years, which means living to 120, which is a crazy notion, right?"
So we now understand biology in a very different way than we did before, and it hasn't translated into the clinic. And so why I co-founded Function Health with my co-founders was to help accelerate this gap, to kind of leapfrog over this ossified system. But we need to change."
Source: https://x.com/newstart_2024/status/1866494146485125614
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