2024 is the highest rates in American history of Alzheimer's

Calley Means: "2024 is the highest rates in American history of Alzheimer's, cancer, autoimmune conditions, heart disease, diabetes, cancer kidney disease, autism. Every single chronic disease you can think of is at an all-time high growing at an increasing rate as we spend more money to treat those conditions so I think what one point we're trying to make is that all the NIH, all the FDA, it's all on accepting that trend as a given.

It's totally washed their hands of it. And how do we find marginal pills to make this a little bit better, not asking why? And that question about Alzheimer's, the point we're trying to make is that when it comes to chronic conditions, which Alzheimer's is, you have to really not ask the Alzheimer's question, you have to ask why that's one branch on this tree, obesity, right, this tree.

And we talk about, and I think Casey has this amazing framework, you can literally look at five biomarkers, the biomarkers of metabolic dysfunction, HDL, triglycerides, blood sugar, blood pressure, and your waistline. And I'm not joking, I'm not being hyperbolic. If we fired every single researcher and canceled every single grant in the US government for all chronic disease research and all nutrition research and created all policy to maximize those five biomarkers in America, you by definition don't have type two diabetes.

You almost have a 0% chance of getting heart disease, you have very close to 0% chance of getting Alzheimer's. You are not obese by definition. Literally, you go down every single chronic condition that is torturing American life. If you're diabetic, you're four times more likely to be depressed or suicidal because there are cells in our head, and diabetes is cellular dysregulation.

So, literally, on the research and the science thing, I think there's great heroes who've been getting into the weeds on the research, but chronic disease, interconnected to basic lifestyle factors. I think this is a political issue honestly. Every American needs to ask is this an incremental issue where we need slightly better pharmaceutical interventions and slightly better research or is this a radical shift of understanding how our bodies are interconnected and understanding that that needs to be a shift in medicine and frankly how we view the environment.

Like that is a question that we actually think is relatively urgent and relatively existential. Modern society is amazing but as Casey said this is dark right now. Like if you believe what Casey's saying about these statistics about chronic disease, and you actually look at the math that we're growing two times with healthcare spitting the rate of GDP, it's the largest and fastest growing industry in the country.

The fastest growing industry in the United States is not AI, it's not tech, it's healthcare. And as it grows, we get sicker, fatter, more depressed, more infertile. It is going to bankrupt the country, and it's not slowing down. So if you actually believe this, believe we need a new paradigm, is it about getting better research or is about actually saying the research is wrong? This whole paradigm of seeing chronic disease and silos is wrong. So I'm sure you can talk more about Alzheimer's, but it's interconnected."