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Can Ivermectin and Fenbendazole really help you against cancer?
What are the differences between the two? Let us know what you think in the comments below!
Ivermectin and fenbendazole are both antiparasitic drugs, but they differ in their chemical structure, the types of parasites they target, and their use across species.
1. Mechanism of Action:
• Ivermectin: Works by binding to glutamate-gated chloride channels in the nervous system of parasites, leading to paralysis and death of the parasite. It primarily affects nematodes and arthropods.
• Fenbendazole: A benzimidazole compound that inhibits the formation of microtubules by binding to tubulin in the parasite’s cells, disrupting cell division and nutrient absorption. It is effective against a broad range of parasites, especially gastrointestinal worms.
2. Parasite Target Spectrum:
• Ivermectin: Effective against nematodes (roundworms) and external parasites like lice and mites. It has a wide spectrum for parasites in both humans and animals but is not effective against tapeworms or flukes.
• Fenbendazole: Broad-spectrum antiparasitic primarily effective against gastrointestinal parasites, including roundworms, hookworms, whipworms, and some tapeworms. It’s mainly used in animals but can target different types of worms than ivermectin.
3. Ivermectin VS Cancer:
• Mechanism of Action: Some studies suggest that ivermectin may have anti-cancer effects by inhibiting the WNT/β-catenin signaling pathway, which is involved in cancer cell proliferation, survival, and metastasis. Ivermectin has also been found to induce apoptosis (cell death) and inhibit the growth of cancer cells in various laboratory models.
4. Fenbendazole VS Cancer:
• Mechanism of Action: Fenbendazole is thought to interfere with the microtubule structure of cancer cells, similar to how it works in parasites. This disruption can prevent cancer cells from dividing and growing. Additionally, it may promote apoptosis and enhance the effectiveness of certain chemotherapy drugs.
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