Professor Angus Dalgleish: The MHRA should stop all the boosters

"The immune system, it does hold the cancer in abeyance...we've known that when severe immune suppression is induced by some other source like HIV cancers appear which would not normally have appeared. So what's happened with this booster. It's a powerful booster designed to induce as many antibodies as possibly can. And the immune system's only got limited resources and it remains in an equilibrium balance. So you're suddenly using an enormous amount of these resources to make antibodies to throw at a virus that's not there and never will be.
And we predicted that if there was a successful coronavirus vaccine, it would only be useful for once because you get this thing called immunological imprinting or antigenic sin. So even if you do put in a new variant, the immune system will only see the response to the first virus and the first vaccine. So the scenario is quite pointless, except by using all these resources, you actually take away for the T cells controlling the cancer...
The cancer patients who received the booster had T cell exhaustion...we have normal cells rise every day and there's millions, millions and there it's very well controlled. And we know this that patients who've had very bad cancer we can give them the new immunotherapies now to boost their T cell responses and they can get complete responses and be under control for years. So this was what was happening with their booster vaccine, it was perturbing this wonderful equilibrium of control and basically interrupting all the resources and it led to a depression of the T cell response...I was amazed at how bad it was in some patients. They used T cell exhaustion, not T cell suppression. Exhaustion that they just been stimulated to the point where they were no longer able to do their job.
And then another paper came out showing that after the booster, not after the 1st and 2nd, the 1st and 2nd induce what we call immunoglobulin subtypes, we call these one and three and these make neutralizing antibodies. But after the booster, many people now have reported that the subtype switches to four. Now what this means instead of attacking a virus with a neutralizing killing, they switch off to a tolerizing one. And IgG4 is exactly the antibody response you want to have if you have a kidney transplant or a liver transplant, you want to tolerize the antibodies so they don't go and attack the new kidney. So all of a sudden this starts falling into place. We're switching off the policeman and then we're tolerizing and so no wonder the cancer is able to escape. But subsequently we found many other disturbing reasons why at the very least and my point is being that the fact that we have a scientific explanation for this.
The fact that we are seeing this should be a red flag and the MHRA should stop all the boosters...."