10 Celebs Who RUINED Their Career with One Joke

These celebrities lost it all in the blink of an eye. Welcome to WatchMojo, and today we’re looking at times high profile individuals severely damaged their star status with just one joke. Our countdown of celebs who ruined their careers with one joke includes Kyle Gass, Kathy Griffin, Roseanne Barr, and more! Which of these ill-conceived jokes from celebrities shocked you the most? Share your thoughts in the comments below.