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Dr. Jessica Rosa about contamination of mRNA vaccines
"The DNA that was used to produce the modified mRNA as per the ingredient, the primary ingredient wrapped in the lipid nanoparticle for injection was made with something called a process one manufacturing procedure, which require the use of PCR to produce the DNA for production of the modified mRNA. The commercial batches that went into people's arms were made with a different manufacturing process called process 2 whereby a plasmid which is a circular DNA E.coli system was used so the DNA is synthesized put into the E.coli bacteria and the power of the doubling time of the bacteria, the fast growing time of the bacteria. It's exploited so as the bacteria grows and doubles every 20 seconds you have more and more DNA which you can then linearize, use in vitro transcription and T7 polymerase to convert to your mRNA and in this case you add in N1 methyl pseudouridine to produce your modified mRNA and then you're supposed to clean out the final product using a DNase so that you degrade all your DNA that is remaining.
Now what we thing happened is that a lot of DNA was left behind which means it wasn't cleaned thoroughly at the end of the process. And one of the ways that this might have happened is by the formation of DNA and RNA hybrids, this is something that happens in nature, it's not new to this procedure at all. And our body has mechanisms to remove these and to get rid of what we call R- loop accumulation which are the introns that get excised out from the DNA when these hybrids form. But if you have R-loop accumulation by introducing massive amounts of these via a lipid nanoparticle for example into a cell you can initiate a number of disease pathways such as cancer."
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