Clostridium Difficile (Antibiotic-Associated Diarrhea) Risk Factors, Symptoms, Diagnosis, Treatment

Clostridium (Clostridioides) Difficile (“Antibiotic -Associated Diarrhea”) | Risk Factors, Symptoms, Diagnosis, Treatment

Clostridium (Clostridioides) Difficile (or “C. Diff”) is a gram positive bacteria that is an important cause of non-inflammatory acute diarrhea. C. difficile infections are more likely in patients who have recently taken certain antibiotics, in patients who have recently been hospitalized and in the elderly. C. difficile also causes a variety of signs and symptoms and complications (including fulminant colitis and toxic megacolon). The diagnosis of C. difficile occurs by stool culture, stool PCR and other methods and the treatment involves antibiotics including metronidazole and vancomycin.

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