Can Benfotiamine Help With Diabetic Nerve Damage?

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Can Benfotiamine Help With Diabetic Nerve Damage?

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Discover the science behind benfotiamine supplementation, and how it can help you fight diabetes and neuropathy.

1) High glucose levels, over time, can lead to DIABETIC NEUROPATHY - or diabetic nerve damage. This can cause pain, tingling, numbness, and muscle weakness. While diabetics are at an increased risk of neuropathy, this condition still affects millions of people worldwide.

2) Benfotiamine is a synthetic derivative of THIAMINE, a.k.a. VITAMIN B1. Thiamine has been shown to improve glucose metabolism, help regulate blood sugar levels, and enhance nerve function, which can reduce the risk of diabetic neuropathy.

3) Thiamine is rapidly metabolized and then excreted from your body, but benfotiamine has been found to exhibit greater BIOAVAILABILITY – so it can more easily be utilized by your cells than vitamin B1, and may have added strength for counteracting various pathological processes involved in diabetic neuropathy.

4) Benfotiamine is LIPID-SOLUBLE, so it passes through the fatty membranes of nerve cells more easily than thiamine, which is water-soluble. Studies have found that benfotiamine is absorbed up to 3.6 times more than thiamine.

5) Benfotiamine acts as an antioxidant inside the body, and it has demonstrated the ability to be an R.O.S SCAVENGER. REACTIVE OXYGEN SPECIES, are highly reactive, unstable molecules that can easily influence other molecules in cells. A toxic build-up of ROS can lead to DNA, RNA, and protein damage in your body. But benfotiamine can collect and expel these harmful molecules from your body before they can build up to toxic levels, thereby reducing oxidative stress and cellular damage in your nerves.

6) Benfotiamine has been found to inhibit the activation of pathways involved in A.G.E. formation, thereby mitigating their detrimental effects on nerve tissues. A.G.E.s can contribute directly to an increase in oxidative stress, arterial plaque, and Reactive Oxygen Species. They are linked to multiple pathogenic disorders, including Alzheimer’s disease, atherosclerosis, and diabetes.

7) Benfotiamine can enhance glucose utilization within cells by activating TRANSKETOLASE, a thiamine-dependent enzyme that plays a role in the metabolism of glucose, which aids the breakdown of glucose into energy for your cells. Longitudinal studies have found that benfotiamine can work to increase insulin sensitivity.
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