Family Guy S11 Ep 12 - Gender Transformations

Season 11 Episode 12 Valentine's Day in Quahog
Following a one-night's stand, Quagmire's date curses him that he'll one day get what he deserves. Following a shock on his date's tampon warmer, he suddenly appears as a woman to everyone else, fooling even Joe who hits on her. When he goes to the doctor, Dr. Hartman wants to give him a pelvic exam. Escaping, Quagmire realizes he has really been cursed and decides to make the best of things by being a lesbian.