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New Target for Treating Degenerative Diseases Like Alzheimer’s and Parkinson’s
Researchers have identified a gene therapy target that could potentially slow the development and progression of degenerative diseases.
Proteins serve as building blocks, receptors, processors, couriers, and catalysts in organisms. A protein’s structure is critical to its function. Misfolded proteins are unable to carry out their tasks and can also accumulate, leading to a variety of incurable degenerate diseases such as Alzheimer’s, Parkinson’s, and retinitis pigmentosa.
In a new paper published by Developmental Cell, researchers from the University of California, Santa Barbara reveal a new connection between the ion transport protein ZIP7 and the cell’s proteasome, which degrades misfolded proteins. This link offers a promising target for treating a variety of degenerative diseases caused by protein misfolding.
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