Love Your Liver Livestream #140_ LACTOFERRIN the _Miracle Molecule_! Subscriber Q&A #toxicbiletheory

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0:00 Intro.

4:38 Studies:
— Lactoferrin: A glycoprotein that plays an active role in human health
— Role of lactoferrin and its receptors on biliary epithelium
— Lactoferrin promotes bile acid metabolism and reduces hepatic cholesterol deposition by inhibiting the farnesoid X receptor (FXR)-mediated enterohepatic axis

33:42 Studies:
— Role of Lactoferrin in Treatment of Bile Duct Ligation-Induced Hepatic Fibrosis in Rats: Impact on Inflammation and TGF-β1/Smad2/α SMA Signaling Pathway
— The Impact of Lactoferrin on the Growth of Intestinal Inhabitant Bacteria
— Lactoferrin modulates gut microbiota and Toll-like receptors (TLRs) in mice with dysbiosis induced by antibiotics
— Lactoferrin Alleviates Inflammation and Regulates Gut Microbiota Composition in H5N1-Infected Mice
— The Impact of Lactoferrin on the Growth of Intestinal Inhabitant Bacteria
— Lactoferrin: A glycoprotein that plays an active role in human health
— Effects of lactoferrin on intestinal flora of metabolic disorder mice
— Daily Dose of Bovine Lactoferrin Prevents Ethanol-Induced Liver Injury and Death in Male Mice by Regulating Hepatic Alcohol Metabolism and Modulating Gut Microbiota
— Lactoferrin Prevents Chronic Alcoholic Injury by Regulating Redox Balance and Lipid Metabolism in Female C57BL/6J Mice
— Unfolding of iron and copper complexes of human lactoferrin and transferrin
— The Lactoferrin Phenomenon - A Miracle Molecule
— A randomized, double-blind, placebo-controlled trial to determine the efficacy and safety of lactoferrin with vitamin E and zinc as an oral therapy for mild to moderate acne vulgaris

1:00:53 Studies:
— PDB ID 3CI8: Crystal structure of the complex of C-lobe of lactoferrin with vitamin B3 (niacin) at 2.4
— Deaths: Leading Causes for 2020 - National Vital Statistics Reports (Volume 72, Number 13)
— Lactoferrin attenuates cardiac fibrosis and cardiac remodeling after myocardial infarction via inhibiting mTORC1/S6K signaling pathway
— Anticancer effects of lactoferrin: underlying mechanisms and future trends in cancer therapy
— Lactoferrin’s Anti-Cancer Properties: Safety, Selectivity, and Wide Range of Action

1:24:58 Studies:
— Lactoferrin, the Moonlighting Protein of Innate Immunity
— Lactoferrin for [C19] prevention, treatment, and recovery
— Lactoferrin as Immune-Enhancement Strategy for SARS-CoV-2 Infection in Alzheimer’s Disease Patients
— Ambulatory [C19] Patients Treated with Lactoferrin as a Supplementary Antiviral Agent: A Preliminary Study

1:39:24 Studies:
— Roles of lactoferrin on skin wound healing
— Optimized lactoferrin as a highly promising treatment for intracerebral hemorrhage: Pre-clinical experience
— Potential of Lactoferrin in the Treatment of Lung Diseases
— A Novel Human Recombinant Lactoferrin Inhibits Lung Adenocarcinoma Cell Growth and Migration with No Cytotoxic Effect on Normal Human Epithelial Cells
— Bovine lactoferrin inhibits lung cancer growth through suppression of both inflammation and expression of vascular endothelial growth factor
— Neuroprotective Effects of Lactoferrin in Alzheimer's and Parkinson's Diseases: A Narrative Review
— Antidiabetic efficacy of lactoferrin in type 2 diabetic pediatrics; controlling impact on PPAR-γ, SIRT-1, and TLR4 downstream signaling pathway
— Kidney protective potential of lactoferrin: pharmacological insights and therapeutic advances
— Lactoferrin Contributes a Renoprotective Effect in Acute Kidney Injury and Early Renal Fibrosis
— Lactoferrin ameliorates carfilzomib-induced renal and pulmonary deficits: Insights to the inflammasome NLRP3/NF-κB and PI3K/Akt/GSK-3β/MAPK axes
— Kidney protective potential of lactoferrin
— Unleashing lactoferrin's antidepressant potential through the PI3K/Akt/mTOR pathway in chronic restraint stress rats
— Lactoferrin deficiency during lactation increases the risk of depressive-like behavior in adult mice

2:06:28 Order of adding stuff.

2:20:54 Studies:
— Differential effects of retinoids on nitric oxide production by promonocytic U937 cells and ZR-75-1 human breast cancer cells
— All-trans-retinoic acid ameliorates atherosclerosis, promotes perivascular adipose tissue browning, and increases adiponectin production in Apo-E mice
— Increased dietary intake of vitamin A promotes aortic valve calcification in vivo

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