Ep. 19: Jacob M. Hands—What's Wrong With Fish Oil (Chocolate too!?!)?

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Introduction
What about fish oil? Is it a problem due to oxidation and contamination? Is it beneficial to health as many claim or is it a PUFA that’s bad for your health?
Jacob recently published an analysis of various fish oils with the team at Consumer Labs, looking at oxidative toxicity and purity of a wide variety of commercially available fish oils.
We discuss omega-3 and health, fish oils and oxidation, the science of seed oils and health, and, as a bonus, the problem with chocolates.
This is definitely a bit of a geek fest, so let me know if you have any questions.
Guest info
Jacob Hands, MD candidate and consultant for Consumer Lab on quality control and testing of supplements, and consultant to Rhonda Patrick, MD, of Found my Fitness.
Consumer Lab https://www.consumerlab.com/
Found my Fitness https://www.foundmyfitness.com/

Biography:
“Medical student passionate about patient care, research, and emerging therapeutics.
“M.D. Candidate at The George Washington University School of Medicine and Health Sciences.”
https://www.linkedin.com/in/jacob-hands-3622619b/

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Looking to fix your diet by getting rid of seed oils?
Check out the Seedy app!
https://www.seedyapp.com/

Tucker Goodrich
Substack: https://tuckergoodrich.substack.com/
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Blog (deprecated, but still a lot there!): http://yelling-stop.blogspot.com/
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Show Notes
Hands, J. M., Anderson, M. L., Cooperman, T., & Frame, L. A. (2023). A Multi-Year Rancidity Analysis of 72 Marine and Microalgal Oil Omega-3 Supplements. Journal of Dietary Supplements, 0(0), 1–12. https://doi.org/10.1080/19390211.2023.2252064
This is the only human study I’m aware of showing harm from eating marine foods. The Japanese and the Eskimos do not suffer from infertility, so I think this gentleman must have been doing something wrong.
“I lived for 100 days on nothing but marine animal food (seal, fish, crustaceans and molluscs) and water; weights of all food were recorded….”
“In seminal fluid, the total amount of prostaglandins decreased significantly and small amounts of the [Ω-]3-series appeared; spermatozoa became immobile and then disappeared.”
Sinclair, H. M. (1981). The Relative Importance of Essential Fatty Acids of the Linoleic and Linolenic Families: Studies with an Eskimo Diet. Progress in Lipid Research, 20, 897–899. https://doi.org/10.1016/0163-7827(81)90167-3
Goodrich, T. D. (2022, April 13). The Folate Experiment [Blog]. Yelling Stop. https://open.substack.com/pub/tuckergoodrich/p/the-folate-experiment
Goodrich, T. (2021, October 19). What Is The Most Fattening Food? [Blog]. Yelling Stop. https://tuckergoodrich.substack.com/p/what-is-the-most-fattening-food
Mozaffarian, D., Hao, T., Rimm, E. B., Willett, W. C., & Hu, F. B. (2011). Changes in Diet and Lifestyle and Long-Term Weight Gain in Women and Men. New England Journal of Medicine, 364(25), 2392–2404. https://doi.org/10.1056/NEJMoa1014296
Zong, G., Liu, G., Willett, W. C., Wanders, A. J., Alssema, M., Zock, P. L., Hu, F. B., & Sun, Q. (2019). Associations Between Linoleic Acid Intake and Incident Type 2 Diabetes Among U.S. Men and Women. Diabetes Care, 42(8), 1406–1413. https://doi.org/10.2337/dc19-0412
Johns, D. M. (2023, April 13). Nutrition Science’s Most Preposterous Result: Could Ice Cream Possibly Be Good for You? The Atlantic, 5/2023. https://www.theatlantic.com/magazine/archive/2023/05/ice-cream-bad-for-you-health-study/673487/
Pearce, N. (2011). Epidemiology in a Changing World: Variation, Causation and Ubiquitous Risk Factors. International Journal of Epidemiology, 40(2), 503–512. https://doi.org/10.1093/ije/dyq257
Huang, Z., Sun, S., Lee, M., Maslov, A. Y., Shi, M., Waldman, S., Marsh, A., Siddiqui, T., Dong, X., Peter, Y., Sadoughi, A., Shah, C., Ye, K., Spivack, S. D., & Vijg, J. (2022). Single-Cell Analysis of Somatic Mutations in Human Bronchial Epithelial Cells in Relation to Aging and Smoking. Nature Genetics, 54(4), Article 4. https://doi.org/10.1038/s41588-022-01035-w

Jacob’s Discussion Notes

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If you have any questions about sources for things discussed please ask in the comments.